Orbital magnetic resonance imaging profile and clinicoradiological correlation in COVID-19-associated rhino-orbital-cerebral mucormycosis: A single-center study of 270 patients from North India코로나19 관련 코뿔소-안와-대뇌 점막진균증의 궤도 자기공명영상 프로파일과 임상방사선학적 상관관계: 북인도 환자 270명을 대상으로 한 단일 센터 연구Article Published on 2022-02-012022-09-11 Journal: Indian journal of ophthalmology [Category] COVID19(2023년), SARS, 치료기술, [키워드] Accuracy age assessment Brain Care clinical evaluation Clinical sign Clinical signs Cohort compartment syndrome consecutive patients correlated correlation COVID-19 cross-sectional cross-sectional study detect diagnostic Diagnostic accuracy edema Evidence evidence of facial feature frontal nerve India infraorbital nerve magnetic resonance imaging male MRI Mucormycosis nasal North orbit orbital wall orbital. Pain paranasal Paranasal sinuses Patient patients periorbital periorbital edema presenting presenting symptom radiological ROCM sensitivity single-center study specificity Study protocol Symptom syndrome Unilateral was performed [DOI] 10.4103/ijo.IJO_1652_21 PMC 바로가기 [Article Type] Article
Performance of RT-qPCR detection of SARS-CoV-2 in unextracted nasopharyngeal samples using the Seegene Allplex TM 2019-nCoV protocolSeegene Allplex TM 2019-nCoV 프로토콜을 사용하여 추출되지 않은 비인두 샘플에서 SARS-CoV-2의 RT-qPCR 검출 성능Article Published on 2022-02-012022-09-11 Journal: Journal of virological methods [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] 2019-nCoV acute respiratory syndrome coronavirus CDC center coefficient consecutive patient consecutive patients Control coronavirus coronavirus 2 COVID-19 Ct cut-off cut-off cut-off value detect diagnostic test diagnostic tests disease control evaluated False positives Interpretation Kappa coefficient measure molecular diagnostics nasopharyngeal sample Nasopharyngeal samples pandemic Pandemics performance prevention protocol real time PCR reducing reduction respiratory resulting RT-qPCR SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spread tested USA Viral viral RNA extraction [DOI] 10.1016/j.jviromet.2021.114429 PMC 바로가기 [Article Type] Article
Awake prone positioning in nonintubated spontaneous breathing ICU patients with acute hypoxemic respiratory failure (PRONELIFE)—protocol for a randomized clinical trial삽관되지 않은 자발 호흡 중환자 중 급성 저산소성 호흡 부전(PROONELIFE) 환자의 깨어 있는 엎드린 자세 - 무작위 임상 시험을 위한 프로토콜Study Protocol Published on 2022-01-102022-09-10 Journal: Trials [Category] 임상, [키워드] Acute hypoxemic respiratory failure Acute respiratory failure all-cause mortality assigned Awake prone positioning benefit Blinding Clinical management clinical trial complications Composite consecutive patients Critically ill Critically ill patient critically ill patients determine duration of use Dyspnea Effect eligible Endpoint enrolment etiology hospital Hypoxemia hypoxemic Hypoxemic respiratory failure ICU ICU patient ICU Patients include International intubation intubation rate invasive invasive ventilation investigator-initiated ISRCTN lung tissue Mortality multicenter noninvasive respiratory Other Oxygenation parameters Patient Pragmatic Prevent primary endpoint Prone position prone positioning randomized clinical trial Randomized controlled trial Randomly reduction in reference number Registered respiratory Respiratory failure secondary Secondary endpoints spontaneous breathing standard care Support Tolerance tracheal tracheal intubation Trial Ventilation [DOI] 10.1186/s13063-021-05991-2 PMC 바로가기 [Article Type] Study Protocol
A randomized pilot study using calcitriol in hospitalized COVID-19 patients입원한 COVID-19 환자에서 칼시트리올을 사용한 무작위 파일럿 연구Randomized Controlled Trial Published on 2022-01-012022-09-11 Journal: Bone [Category] SARS, 비임상, 임상, [키워드] 1:1 14 subject 14 subjects adaptive Admission arterial oxygen saturation assigned average benefit breath calcitriol calculated clinical marker clinical trial consecutive patients control group COVID-19 death discharge discharged Endocrine enrolled Enrollment expression FiO2 fraction groups Health care health care systems hospital hospital discharge Hospitalization Hospitalized hospitalized COVID-19 patient hospitalized patient hospitalized patients ICU immune function include open label Other oxygen oxygen saturation oxygen supplementation Oxygenation Patient patients hospitalized patients with COVID-19 physiologic function pilot study Randomized randomized clinical trial randomized trial Randomly readmission regulate Regulation required room air SARS-COV-2 infection subject systemic illness therapy transfer treated Treatment Trial Vitamin D with COVID-19 [DOI] 10.1016/j.bone.2021.116175 PMC 바로가기 [Article Type] Randomized Controlled Trial
Combined epidemiological and genomic analysis of nosocomial SARS-CoV-2 infection early in the pandemic and the role of unidentified cases in transmission전염병 초기 병원 SARS-CoV-2 감염의 역학 및 게놈 통합 분석과 전염에서 미확인 사례의 역할Article Published on 2022-01-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] MERS, SARS, 유전자 메커니즘, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission Admissions analysed Asymptomatic asymptomatic patients case ascertainment Cluster Clusters Combined Community consecutive patients coronavirus Coronavirus 2019 COVID-19 creating Diagnosis early stage early stages epidemiological epidemiological data epidemiologically Evidence evidence of Face mask Face masks facilitated Factor Final genome sequence Genomic analysis genomic data Genomics Haplotype healthcare healthcare worker Healthcare workers Healthcare-associated infection hospital implicated incidence increase infection control limit median Molecular epidemiology multisite nosocomial Nosocomial transmission pandemic per day positive PCR test respiratory SARS-CoV-2 SARS-CoV-2 genome sequence SARS-CoV-2 genome sequences SARS-COV-2 infection sequenced Sequencing severe acute respiratory syndrome Coronavirus Support Transmission transmission cluster transmission clusters vector Viral viral genome sequence whole-genome sequencing with infection [DOI] 10.1016/j.cmi.2021.07.040 PMC 바로가기 [Article Type] Article
Tocilizumab improves 28-day survival in hospitalized patients with severe COVID-19: an open label, prospective study토 실리 주맙Research Published on 2021-12-222022-09-01 Journal: Respiratory Research [Category] 진단, [키워드] 28-day mortality 95% CI Administered allocation Analysis Clinical outcome clinical outcomes consecutive patient consecutive patients COVID-19 discharge Efficacy evaluated finding FiO2 hospital discharge hospitalized patient hospitalized patients IMPROVE Mortality open open label outcome outcomes PaO PaO2/FiO2 Patient Primary outcome progression Prospective Study receiving secondary Secondary outcomes severe COVID-19 significant increase significantly higher significantly lower statistically significant difference supplementary material survival systemic inflammatory marker Tocilizumab usual care usual care alone usual care group WHO with COVID-19 [DOI] 10.1186/s12931-021-01914-6 PMC 바로가기 [Article Type] Research
Tracheostomies after SARS-CoV-2 intubation, performed by academic otorhinolaryngologists in the Paris area of France: Preliminary resultsObservational Study Published on 2021-12-012022-10-05 Journal: European annals of otorhinolaryngology, head and neck diseases [Category] SARS, 임상, [키워드] abnormality absence Characteristics clinical feature Complication condition consecutive patients Contamination COVID-19 death evaluate evaluated flexible France heterogeneity indication Infection intubation laryngeal lesion lesions material multicentre no significant difference occurred Occurrence operator Otorhinolaryngology Paris patients performed postoperative Postoperative complication retrospective Retrospective study SARS-CoV-2 secondary specificity surgical Symptom the patient tracheostomy Univariate analysis university hospital ventilatory with COVID-19 [DOI] 10.1016/j.anorl.2021.03.002 PMC 바로가기 [Article Type] Observational Study
Blood Hemoglobin Substantially Modulates the Impact of Gender, Morbid Obesity, and Hyperglycemia on COVID-19 Death Risk: A Multicenter Study in Italy and SpainEndocrinology Published on 2021-11-022022-10-31 Journal: Frontiers in Endocrinology [Category] COVID-19, MERS, [키워드] Admission affecting Algorithms Analysis Barcelona Bilirubin Blood clinical setting clinician Concentration confounding factor consecutive patients COVID-19 death Effect Epidemiology evaluate evaluated expected female help hemoglobin hyperglycemia ICU ICU admission identify Impact increased mortality independent predictor individual intensive care Interaction Italy Logistic regression machine learning men modulate modulating monitoring Morbid morbidly obese Mortality multicenter study no difference obesity Patient patients with COVID-19 Prognostic value protective effect Result risk Rome serum Sex Spain subject subjects the median with COVID-19 worse prognosis [DOI] 10.3389/fendo.2021.741248 PMC 바로가기 [Article Type] Endocrinology
Anaesthesia protocol evaluation of the videolaryngoscopy with the McGrath MAC and direct laryngoscopy for tracheal intubation in 1000 patients undergoing rapid sequence induction: the randomised multicentre LARA trial study protocol빠른 시퀀스 유도를 받는 1000명의 환자에서 McGrath MAC을 사용한 비디오 후두경 및 기관 삽관을 위한 직접 후두경의 마취 프로토콜 평가: 무작위 다기관 LARA 시험 연구 프로토콜Article Published on 2021-10-062022-09-11 Journal: BMJ Open [Category] SARS, 임상, 치료기술, [키워드] 90% power adult anaesthesia adult intensive & adverse events airway airway management anaesthesia approved aspiration chance consecutive patients Controlled trial COVID-19 pandemic Critical Critical care cuff direct laryngoscopy endotracheal tube Ethics expected glottis healthcare worker high risk include increased risk indicated Intensive International intubation Local local Ethics Committee Macintosh manuscript medical association multicentre National opening Patient percentage primary endpoint Protective protocol pulmonary aspiration randomised randomised controlled trial Randomly Rapid Rapid sequence induction reduce registration number Rhineland score secondary endpoint Secondary endpoints sequence significance level Study protocol surgery surgical technique the primary endpoint tracheal tracheal intubation Trial university videolaryngoscopy Visualisation [DOI] 10.1136/bmjopen-2021-052977 PMC 바로가기 [Article Type] Article
Cerebral venous sinus thrombosis associated with COVID-19: a case series and literature reviewCOVID-19와 관련된 대뇌정맥동 혈전증: 사례 시리즈 및 문헌 검토Review Published on 2021-10-012022-09-11 Journal: Journal of Neurology [Category] SARS, 치료기술, [키워드] Abstract case sery center cerebral Characteristics clinical manifestation clinical manifestations clinically suspected confirmatory tests consecutive patients coronavirus COVID-19 COVID-19 pandemic COVID-19 symptoms demographics Diagnosis diagnosis of SARS-CoV-2 Diagnostic Criteria Factor had no Hemorrhagic hospital infected individuals Infection Intracranial investigated Iran literature review mortality rate nasopharyngeal sample North Older Oropharyngeal outcomes Patient patients patients died Practitioner practitioners radiological radiological feature receiving reported respiratory symptom respiratory symptoms SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 infected individuals SARS-COV-2 infection searched Sinus Sinus thrombosis South stroke Therapeutic strategies thrombosis venous venous sinus West with COVID-19 [DOI] 10.1007/s00415-021-10450-8 PMC 바로가기 [Article Type] Review