Singleplex, multiplex and pooled sample real-time RT-PCR assays for detection of SARS-CoV-2 in an occupational medicine settingArticle Published on 2022-10-222022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] 2019-nCoV addition Analysis Asymptomatic CDC clinical sample condition Contact COVID COVID-19 COVID-19 disease Critical defined Detection limit diagnostic diagnostic test disease equipment FDA flexible healthcare high risk implication include Infection limit methodology multiplex overlap pandemic Pandemics Panel Patient Population positive sample progressed reagent real-time RT-PCR resource resources RT-PCR SARS-CoV-2 sensitivity spread of COVID-19 symptomatic Symptomatic patients tested Transmission was determined [DOI] 10.1038/s41598-022-22106-2 PMC 바로가기
Evidence for the spread of SARS-CoV-2 and olfactory cell lineage impairment in close-contact infection Syrian hamster modelsArticle Published on 2022-10-212022-11-15 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID19(2023년), SARS, 치료기술, [키워드] addition Administered assigned caused Cell cells changes in close contact complication of COVID-19 Contact days post infection detectable examined group groups hamster highest immature Impact impairment indicated Infection Lineage lung lung damage lung; nose occurred olfactory Olfactory epithelium olfactory receptor cells ORN ORNs pathogenesis of COVID-19 patients with COVID-19 receptor SARS-CoV-2 short-term cohabitation. significantly Spread subsequent tissue tissue damage transmitted uninfected unique Viral load viral presence Viral transmission virus [DOI] 10.3389/fcimb.2022.1019723 PMC 바로가기
Individual-based modeling reveals that the COVID-19 isolation period can be shortened by community vaccinationArticle Published on 2022-10-202022-11-16 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI approach B.1.617.2 baseline BNT162b2 vaccine booster vaccination Community Contact COVID-19 Delta Effect effective vaccine emotional Impact individual infected individual infected individuals Infection Isolation less likelihood mitigate nonpharmaceutical intervention occur outbreak profile Psychological quarantine reduce reveal risk Secondary infection subsequent sustained the patient the SARS-CoV-2 Transmission transmission of SARS-CoV-2 vaccination Vaccine-induced immunity variant Viral load [DOI] 10.1038/s41598-022-21645-y PMC 바로가기
The SARS-CoV-2 Infection Among Students in the University of Porto: A Cross-Sectional StudyArticle Published on 2022-10-202022-11-15 Journal: International Journal of Public Health [Category] COVID19(2023년), SARS, 진단, [키워드] 95% CI age antibodies applied Bayesian inference Contact Evidence groups IgG IgG antibody IgM Immunoglobulin immunological Infection International interval Local male Molecular diagnosis molecular test Older point of care Porto Prevalence quarantine questionnaire reactive reported risk SARS-CoV-2 SARS-CoV-2 specific antibody Seroepidemiology Seroprevalence significantly higher student Symptoms university university students. was performed [DOI] 10.3389/ijph.2022.1604548 PMC 바로가기
The Potential Role of an Adjunctive Real-Time Locating System in Preventing Secondary Transmission of SARS-CoV-2 in a Hospital Environment: Retrospective Case-Control StudyArticle Published on 2022-10-182022-11-16 Journal: Journal of Medical Internet Research [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% CI adjusted odds ratio Analysis approach case-control study conducted Contact Contact tracing COVID-19 COVID-19 patients diagnosed hospital In-hospital infection control limitation multivariable logistic regression performed positive Potential Preventing primary endpoint real-time locating system reduce retrospective role SARS-CoV-2 secondary secondary transmission secondary transmission. South Korea System university hospital Validity [DOI] 10.2196/41395 PMC 바로가기
Point-of-care detection of SARS-CoV-2 antigen among symptomatic vs. asymptomatic persons: Testing for COVID-19 vs. infectivityArticle Published on 2022-10-172022-11-15 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% confidence interval acute respiratory syndrome Ag-RDT Antigen Asymptomatic Buenos Aires Care caused Concordance Contact coronavirus disease Coronavirus-2 COVID-19 COVID-19 patient detect diagnose diagnostic evaluate false-negative hypothetical identify individual Infectious virus Isolation pandemic Participants PCR point-of-care positive public health qRT-PCR rapid antigen testing real-time RT-PCR SARS-CoV-2 SARS-CoV-2 antigen SARS-COV-2 infection SARS-CoV-2 RNA SARS-CoV-2 testing subjects Surveillance symptomatic t -value Testing threshold Transmission utility viral kinetics viral kinetics. was obtained [DOI] 10.3389/fpubh.2022.995249 PMC 바로가기
Broad-Spectrum Extracellular Antiviral Properties of Cucurbit[ n]urilsArticle Published on 2022-10-142022-11-15 Journal: ACS Infectious Diseases [Category] COVID19(2023년), SARS, 치료제, [키워드] acting amino acids Antiviral Antiviral compound Antiviral effect antivirals Cell Compound compounds Contact cucurbituril disease dose−response Efficacy Extracellular herpes simplex homologue Interaction investigated macrocycle mechanism morbidity Mortality nontoxic pathogen property Protein respiratory syncytial virus responsible RSV SARS-CoV-2 viral surface virucidal virus viruses virustatic. [DOI] 10.1021/acsinfecdis.2c00186 PMC 바로가기
Surveillance, contact tracing and characteristics of SARS-CoV-2 transmission in educational settings in Northern Italy, September 2020 to April 2021Article Published on 2022-10-102022-11-16 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha variant Analysis attack rate calculated Characteristics Contact Contact tracing COVID-19 case Effectiveness elapsed identify implementation index case investigated Italy no difference occurred positive reduced remained risk of transmission SARS-CoV-2 SARS-CoV-2 transmission secondary secondary case Seven source of infection speed Spread study period surveillance data Swab test the epidemic Transmission virus was determined [DOI] 10.1371/journal.pone.0275667 PMC 바로가기
The interplay between the airway epithelium and tissue macrophages during the SARS-CoV-2 infectionArticle Published on 2022-10-062022-11-15 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료제, [키워드] 3D cultures activate added Air-liquid interface air-liquid interface (ALI) airway airway epithelium Antigen presentation antiviral immune response basolateral side cell type co-culture Contact Course Culture cytokine production cytokine release demonstrated driven by epithelial epithelial cells evaluate HAE hMDM hMDMs Human airway epithelium human airway epithelium (HAE) human monocyte-derived macrophage immune response in viral infected cell Infection Innate immunity lung Macrophage macrophages macrophages. phagocyte primary human airway recruitment Replication SARS-CoV-2 SARS-COV-2 infection Spread the SARS-CoV-2 tissue macrophage transfer virus virus replication [DOI] 10.3389/fimmu.2022.991991 PMC 바로가기
Evaluation of the relative potential for contact and doffing transmission of SARS-CoV-2 by a range of personal protective equipment materialsArticle Published on 2022-10-052022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 치료제, [키워드] acute respiratory syndrome Adsorption aerosol analysed antiviral potency caused Community Contact coronavirus coronavirus disease correlation doffing Efficacy equipment evaluated global public health healthcare Infection Ion m/z negative correlation no correlation Personal protective equipment Physicochemical properties Polymer positive PPE Protective reduction in Regression model SARS-CoV-2 transmission the SARS-CoV-2 titre Transmission transmission of SARS-CoV-2 virion virus while [DOI] 10.1038/s41598-022-20952-8 PMC 바로가기