Systematic review of host genetic association with Covid-19 prognosis and susceptibility: What have we learned in 2020?Covid-19 예후 및 감수성과 숙주 유전적 연관성에 대한 체계적인 검토: 2020년에 우리는 무엇을 배웠습니까?Review Published on 2022-03-012022-09-11 Journal: Reviews in Medical Virology [Category] SARS, 변종, [키워드] ABO ACE1 ACE2 analyzed ApoE association associations available data candidate candidate gene candidate genetic variants claimed clinical manifestation complex interaction COVID-19 COVID-19 prognosis COVID-19 severity database disease Effects eligible environmental factors evaluated examined Exome exome sequencing FIVE furin Genes Genetic genetic association Genetic association studies genetic variants GWAS Health healthcare heterogeneous HLA Host IFITM3 IFNL3 IFNL4 IMPROVE indicated Infection locus Meta-analysis moderate outcome outcomes pathophysiology performed Polymorphisms predict Prognosis recommendations reduce replicate Replication reported Research SARS-CoV-2 SARS-COV-2 infection Sequencing severity susceptibility TMPRSS2 whole-genome [DOI] 10.1002/rmv.2283 PMC 바로가기 [Article Type] Review
Physiological health indexes predict deterioration and mortality in patients with COVID-19: a comparative studyResearch Paper Published on 2022-02-282023-06-10 Journal: Aging (Albany NY) [Category] MERS, [키워드] biological age COVID-19 COVID-19 outcome COVID-19 prognosis pandemic SARS-CoV-2 [DOI] 10.18632/aging.203915 PMC 바로가기 [Article Type] Research Paper
High-dose vitamin D substitution in patients with COVID-19: study protocol for a randomized, double-blind, placebo-controlled, multi-center study—VitCov TrialCOVID-19 환자의 고용량 비타민 D 대체: 무작위, 이중 맹검, 위약 대조, 다기관 연구를 위한 연구 프로토콜 - VitCov 시험Study Protocol Published on 2022-02-042022-09-10 Journal: Trials [Category] COVID19(2023년), MERS, SARS, 임상, [키워드] Acute respiratory failure age approach association Case series caused Comorbidities condition coronavirus coronavirus disease Course COVID-19 COVID-19 patients COVID-19 prognosis COVID-19 severity Critically ill deaths deficiency double-blind Efficacy and safety Ethnicity Evidence Factor faster followed by High-dose hospital Hospital stay Hypothesis immunomodulatory properties IMPROVE include intensive care investigated Male sex obesity old age outcome outcomes pandemic Patient patients with COVID-19 Placebo placebo-controlled poor prognosis Randomized Randomized controlled trial reducing reported Respiratory failure risk factor SARS-CoV-2 single dose Study protocol Support Tau the disease therapeutic effect treated Treatment treatment as usual treatment guideline Trial Trial registration Vitamin Vitamin D vitamin D deficiency Vitamin D supplementation vitamin D-deficient patient vitamin D-deficient patients with COVID-19 [DOI] 10.1186/s13063-022-06016-2 PMC 바로가기 [Article Type] Study Protocol
Effective deep learning approaches for predicting COVID-19 outcomes from chest computed tomography volumes흉부 컴퓨터 단층 촬영 부피에서 Covid-19 결과를 예측하기위한 효과적인 딥 러닝 접근Article Published on 2022-02-022022-09-01 Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] aggregate Algorithm approach artificial intelligence AUC automated Chest computed tomography Chest CT Clinical data clinically Combination Computed tomography Computer science coronavirus disease COVID-19 COVID-19 diagnosis COVID-19 patients COVID-19 pneumonia COVID-19 prognosis deep learning develop effective Evolution feature healthy IMPROVE joint lung Metadata Mortality Novel coronavirus novel coronavirus disease Numerous other viral pneumonia outcome pandemic participant Pneumonia predict problems Prognosis pulmonary lesion pulmonary lesions reduce risk stratification Transmission viral infection Viral pneumonia Volume volumetric [DOI] 10.1038/s41598-022-05532-0 PMC 바로가기 [Article Type] Article
Prognostic Significance of Urinary Biomarkers in Patients Hospitalized With COVID-19COVID-19로 입원한 환자의 요도 바이오마커의 예후적 의미Article Published on 2022-02-012022-09-11 Journal: American journal of kidney diseases : the official [Category] COVID19(2023년), SARS, 바이오마커, [키워드] Acute kidney injury Acute kidney injury (AKI) acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 AKI association Biomarker Chronic kidney disease chronic kidney disease (CKD) cohort study Combination comparable Composite coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 COVID-19 patient COVID-19 prognosis Cox proportional hazard creatinine death defined dialysis discrimination EGF elevated epidermal epidermal growth factor epidermal growth factor (EGF) events Evidence evidence of growth factor highest Hospital admission Hospitalized Improving individual Inflammation Inflammatory Inflammatory marker information Injury investigated KDIGO kidney Kidney disease Kidney injury kidney injury molecule 1 (KIM-1) lower risk MCP-1 Microscopy moderate MONITOR monocyte monocyte chemoattractant protein 1 monocyte chemoattractant protein 1 (MCP-1) neutrophil neutrophil gelatinase-associated lipocalin (NGAL) outcome outcomes Patient patients patients hospitalized patients with COVID-19 Primary outcome prognostic progression Prospective prospective cohort study Protein provided rationale repair respiratory risk Sample size serum creatinine setting severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Significance small sample size subclinical AKI tubular injury Urinalysis urinary urinary biomarkers Urine urine microscopy. with COVID-19 [DOI] 10.1053/j.ajkd.2021.09.008 PMC 바로가기 [Article Type] Article
COVID-19 and liver dysfunction: Epidemiology, association and potential mechanismsReview article Published on 2022-02-012022-10-05 Journal: Clinics and research in hepatology and gastroenter [Category] COVID19(2023년), SARS, 바이오마커, 치료제, [키워드] acute respiratory syndrome association caused complex confirmed case coronavirus coronavirus disease COVID-19 COVID-19 case COVID-19 patient COVID-19 patients COVID-19 prognosis Cytokine storm death Drug-induced liver injury Epidemiology Infection Injury Kidney injury liver Liver disease liver diseases liver dysfunction Liver injury mechanism Mortality Multi-organ damage Odds ratio Patient potential mechanism Prevalence Prognosis reported risk severity systematic review [DOI] 10.1016/j.clinre.2021.101793 [Article Type] Review article
Viral Load in COVID-19 Patients: Implications for Prognosis and Vaccine Efficacy in the Context of Emerging SARS-CoV-2 VariantsMedicine Published on 2022-01-312022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory syndrome animal model catastrophic caused Characteristics characterized clinical study Context coronavirus coronavirus disease COVID-19 COVID-19 patients COVID-19 prognosis COVID-19 severity cumulative disease severity Efficacy emerging variants Evidence group highlighting indicated individuals lethality load pandemic Prognosis public health crisis Research SARS-CoV-2 SARS-COV-2 infection Spread the SARS-CoV-2 Transmissibility vaccinated individuals Vaccine Vaccines variants of concern variants of SARS-CoV-2 Viral load VOCs [DOI] 10.3389/fmed.2021.836826 PMC 바로가기 [Article Type] Medicine
Effect of Coronary Artery Disease on COVID-19—Prognosis and Risk Assessment: A Systematic Review and Meta-AnalysisArticle Published on 2022-01-292022-10-28 Journal: Biology [Category] COVID-19, [키워드] Admission affecting Artery association CAD cardiovascular event chronic inflammation Coronary Coronary artery Coronary artery disease coronary syndrome Course COVID-19 COVID-19 prognosis database death determine died disease Effect Factor group incidence Infection intensive care Meta-analysis Mortality non-severe group non-survivor Novel coronavirus Occurrence outcomes Patient patients performed retrospective review risk of bia rupture searched severity of COVID-19 shown simple statistically significant survivor systematic review the SARS-CoV-2 Thromboembolic event total population Trial vessel wall Web of Science [DOI] 10.3390/biology11020221 PMC 바로가기 [Article Type] Article
Potential Immune Indicators for Predicting the Prognosis of COVID-19 and Trauma: Similarities and DisparitiesImmunology Published on 2022-01-202022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, [키워드] Affect alteration C-reactive protein cellular and molecular Complication complications COVID-19 COVID-19 prognosis COVID-19 symptom CTL cytokine disease disparity ferritin help IFNs IL-1 IL-10 IL-4 IL-6 immune Immune cell immune system Indicator inflammatory disease inflammatory mediator inflammatory property monocyte neutrophil outcomes Pathogenesis patients with COVID-19 polyphasic Potential predict procalcitonin Prognosis prognostic indicator researcher serum amyloid severity of COVID-19 similarity subsequent subtype T cell Th1 Th17 Th2 TNF-α trauma Treg various inflammatory disease [DOI] 10.3389/fimmu.2021.785946 PMC 바로가기 [Article Type] Immunology
Biomarker candidates for progression and clinical management of COVID-19 associated pneumonia at time of admission입원 시점에 COVID-19 관련 폐렴의 진행 및 임상 관리를위한 바이오 마커 후보Article Published on 2022-01-122022-09-10 Journal: Scientific Reports [Category] 바이오마커, 치료기술, 치료법, [키워드] administration Admission Biomarker Biomarkers candidate Candidates change Clinical management Clinical practice Coagulation COG5 complement Control COVID-19 COVID-19 prognosis Critical critical condition critical patients differentially expressed Evolution expression FDR FIVE glucocorticoid Glucocorticoids group Hospital admission Hospital stay hospitalized COVID-19 identify immunoglobulins Infectious diseases Inflammation Lipid metabolism MOST OAS3 over-expressed pathophysiology Patient patients plasma sample plasma samples Pneumonia Potential biomarker potential biomarkers priority Prognosis Prognostic factor progression Protein proteome reached Sample selected specific treatment Study design subject therapeutic strategy therapy Tocilizumab Treatment were used [DOI] 10.1038/s41598-021-04683-w PMC 바로가기 [Article Type] Article