Chitinase-3-like protein-1 at hospital admission predicts COVID-19 outcome: a prospective cohort study Research Published on 2022-05-092022-10-05 Journal: Scientific Reports [Category] 바이오마커, 치료법, [키워드] admitted to ICU adverse outcome age Analysis CHI3L1 Clinical outcome collected Comorbidities Control controls COVID-19 COVID-19 patient Cox regression analysis death died disease disease onset disease severity elicit evaluated healthy volunteer Hospital admission ICU inflammatory stimuli initial intensive care involved Kaplan–Meier log rank test non-ICU outcome Patient plasma predict Primary outcome Prognosis prospective cohort study Sex significantly higher survivor symptom onset systemic inflammation the median tissue damage transfer was collected [DOI] 10.1038/s41598-022-11532-x [Article Type] Research
Survival analysis of COVID-19 patients in Ethiopia: A hospital-based studyObservational Study Published on 2022-05-092022-10-05 Journal: PLoS ONE [Category] 임상, [키워드] Admission admitted to ICU age analyzed Care carried chronic chronic kidney diseases chronic obstructive Clinical characteristics close monitoring confidence COVID-19 COVID-19 case COVID-19 disease COVID-19 patient Cox regression analysis death deaths Final global public health hazard high mortality higher risk HIV/AIDS Hospitalization Hospitalized hospitalized patient independent risk factor interval intranasal Kidney disease laboratory-confirmed majority median medical record Mortality mortality rate nine Observational cohort study occurred Older oxygen Patient patients hospitalized performed predictor Probability pulmonary disease Ratio retrospective risk risk of death Sociodemographic survival survival analysis the patient those with comorbidity treated Treatment zone [DOI] 10.1371/journal.pone.0268280 PMC 바로가기 [Article Type] Observational Study
Use of combined treatment of 3rd-generation cephalosporin, azithromycin and antiviral agents on moderate SARs-CoV-2 patients in South Korea: A retrospective cohort study한국에서 중등도 SARs-CoV-2 환자에 대한 3세대 세팔로스포린, 아지트로마이신 및 항바이러스제 병용 치료: 후향적 코호트 연구Article Published on 2022-05-042022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 치료제, [키워드] adjust administration adverse event Analysis analyzed Antibiotics antiviral agent Antiviral agents association Azithromycin baseline characteristics cephalosporin Clinical outcome Cohort cohorts Combined combined treatment conducted confounding factors COVID-19 COVID-19 patient Cox regression analysis Cox regression method death Efficacy and safety Endpoint endpoints Evidence groups hazard ratio hazard ratios Hospital stay Hydroxychloroquine inclusion criteria Kaplan-Meier Kaplan-Meier curve Kaplan-Meier curves laboratory-confirmed Lopinavir Lopinavir/ritonavir low-dose mild to moderate Mild to moderate COVID-19 moderate Moderate COVID-19 moderate COVID-19 patients no significant difference no significant differences not significant Patient performed Prevent Propensity score propensity score matching PSM retrospective cohort study Ritonavir SARS-CoV-2 SARS-CoV-2 patient SARS-CoV-2 patients significant differences South South Korea Standard standard supportive care statistical significance Supportive treatment symptom resolution Time to symptom resolution Treatment treatment arm treatment group viral clearance were used [DOI] 10.1371/journal.pone.0267645 PMC 바로가기 [Article Type] Article
Comprehensive Oncogenic Features of Coronavirus Receptors in Glioblastoma Multiforme다형성 교모세포종에서 코로나바이러스 수용체의 포괄적인 발암성 특징Article Published on 2022-04-062022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 진단, [키워드] ACE2 Analysis ANPEP approaches association bioinformatics Brain brain tissue Cancer caused clinical development Comprehensive coronavirus COVID-19 COVID-19 outbreak COVID-19 pandemic Cox regression analysis demonstrated DPP4 ENPEP expression functional GBM health system immune infiltration incidence individuals Kaplan-Meier survival curve molecular monocyte mRNA oncogenic Patient performed poor prognosis positively correlated potential therapeutic target protein level protein-protein interaction receptor receptors SARS-CoV-2 SARS-COV-2 infection signaling pathway significantly increased survival TMPRSS2 [DOI] 10.3389/fimmu.2022.840785 PMC 바로가기 [Article Type] Article
Combined Role of Troponin and Natriuretic Peptides Measurements in Patients With Covid-19 (from the Cardio-COVID-Italy Multicenter Study)Research article Published on 2022-03-012022-10-05 Journal: The American journal of cardiology [Category] SARS, 바이오마커, [키워드] 95% confidence interval Acute heart failure Admission age available data Biomarker Chronic kidney disease Combined concerning consecutive patient coronary syndrome COVID-19 patients Cox regression analysis death defined Diagnosis died elevated evaluate follow-up period Gender greater hazard ratio higher risk hospitalized COVID-19 patients limit measurement median men multicenter study Natriuretic oxygen saturation Patient patients with COVID-19 peptide Predictive prognostic Prognostic value provided recruited remained risk stratification role troponin troponin level were excluded with COVID-19 worse prognosis [DOI] 10.1016/j.amjcard.2021.11.054 [Article Type] Research article
Predictor factors for non-invasive mechanical ventilation failure in severe COVID-19 patients in the intensive care unit: a single-center retrospective studyOriginal Article Published on 2022-02-152022-10-30 Journal: Journal of Anesthesia, Analgesia and Critical Care [Category] COVID-19, [키워드] adjusted admitted to ICU anonymously applied ARDS Charlson Comorbidity Index collected COVID-19 Cox regression analysis CPK critical COVID-19 patient demographic Endotracheal intubation Factor ICU ICU admission INR intensive care intensive care unit Laboratory laboratory feature mechanical ventilation median median value medical record NIV Non-invasive non-invasive mechanical ventilation non-invasive ventilation outcome Pandemia PaO predict Predictive predictive factor predictor Result retrospective Retrospective study risk severe COVID-19 severe COVID-19 patient single-center supplementary material supported variable was performed [DOI] 10.1186/s44158-022-00038-7 PMC 바로가기 [Article Type] Original Article
Abnormal liver chemistries as a predictor of COVID-19 severity and clinical outcomes in hospitalized patientsObservational Study Published on 2022-02-072022-10-04 Journal: World journal of gastroenterology [Category] 임상, [키워드] abnormality acute respiratory syndrome adjusted Admission alanine aminotransferase albumin level alkaline phosphatase ALP ALT Asian Aspartate aminotransferase association AST Baltimore Bilirubin bilirubin. can be used Clinical characteristics Clinical outcome collected coronavirus COVID-19 COVID-19 patient COVID-19 severity Cox regression Cox regression analysis demographic disease severity drugs elevated Factor highest Hospital admission Hospitalization Hospitalized hospitalized patient in-hospital mortality Johns Hopkin Laboratory liver Liver injury Liver tests Measures mechanical ventilation mortality risk obesity Older age Other outcome Patient patients patients with COVID-19 predict Prevalence prevalent Prognosis retrospective risk serum severe acute respiratory syndrome coronavirus 2 severity severity and prognosis severity of COVID-19 System the patient therapy total bilirubin Treatment United States variable was used with COVID-19 [DOI] 10.3748/wjg.v28.i5.570 PMC 바로가기 [Article Type] Observational Study
Association of a Third Dose of BNT162b2 Vaccine With Incidence of SARS-CoV-2 Infection Among Health Care Workers in Israel이스라엘의 의료 종사자 중 SARS-CoV-2 감염 발생률이 있는 BNT162b2 백신 3차 접종의 연관성Article Published on 2022-01-252022-09-12 Journal: JAMA [Category] 진단, [키워드] 95% CI adjusted hazard ratio administration age Analysis association Aviv baseline BNT162b2 booster dose conducted Cox regression Cox regression analysis Effectiveness enrolled Enrollment Final Follow-up hazard ratio Health care worker health care workers IgG titer incidence rate individual IQR lower risk median occurred of BNT162b2 Older outcome participant Participants Pfizer-BioNTech Primary outcome prospective cohort study Protein receiving Receptor binding domain reported required SARS-CoV-2 SARS-COV-2 infection Screening significantly significantly lower single center study cohort study enrollment Surveillance symptomatic the median vaccinated individual vaccination Vaccine was performed was used women worker [DOI] 10.1001/jama.2021.23641 PMC 바로가기 [Article Type] Article
Efficacy and Safety of Remdesivir in COVID-19 Positive Dialysis PatientsArticle Published on 2022-01-252022-10-27 Journal: Antibiotics [Category] COVID-19, [키워드] 30-Day mortality Administered administration adverse effects adverse events ALT benefit biochemical C-reactive protein change Clinical outcome consequence COVID-19 COVID-19 infections Cox regression analysis death rate determine develop Diagnosis dialysis diarrhea did not reduce died dose Effectiveness Efficacy endpoints ESRD evaluate ferritin Hemodialysis hospital In-hospital Infection Kaplan–Meier analysis lactate dehydrogenase less Liver function Mortality Nasopharyngeal swab onset of symptoms outcome Oxygen requirements Patient patients patients with COVID-19 predictor Probability protocol Remdesivir renal risk Safety safety endpoint serum CRP Study design Support survival survived survivor Toxicity Treatment variable was used with COVID-19 [DOI] 10.3390/antibiotics11020156 PMC 바로가기 [Article Type] Article
Harmonized D-dimer levels upon admission for prognosis of COVID-19 severity: Results from a Spanish multicenter registry (BIOCOVID-Spain study)COVID-19 심각도의 예후를 위해 입원 시 조화된 D-dimer 수준: 스페인 다기관 등록의 결과(BIOCOVID-스페인 연구)Multicenter Study Published on 2022-01-012022-09-11 Journal: Journal of Thrombosis and Thrombolysis [Category] 바이오마커, [키워드] adjusted hazard ratio Admission an area Analysis approach assays association characteristic Clinical practice Coagulopathy comparability COVID-19 COVID-19 patients Cox regression analysis cut-off value D-dimer D-dimer level D-dimer levels death defined dimer Endpoint FEU greater harmonization hospital mortality rate in-hospital mortality in-hospital mortality rate independent Mortality mortality rate multicenter patients Prognosis prognostic receiver operating characteristic regression line reported Result Retrospective multicenter study risk severity Spanish study population test results transformation translate was performed [DOI] 10.1007/s11239-021-02527-y PMC 바로가기 [Article Type] Multicenter Study