SARS-CoV-2 escapes direct NK cell killing through Nsp1-mediated downregulation of ligands for NKG2DArticle Published on 2022-12-272023-07-11 Journal: Cell Reports [Category] COVID19(2023년), [키워드] antiviral immunity COVID-19 CP: Immunology CP: Microbiology Immune escape Innate immunity Natural killer cells NK cells NKG2D nsp1 SARS-CoV-2 [DOI] 10.1016/j.celrep.2022.111892 PMC 바로가기
Rational identification of potent and broad sarbecovirus-neutralizing antibody cocktails from SARS convalescentsArticle Published on 2022-12-202023-07-11 Journal: Cell Reports [Category] COVID19(2023년), [키워드] antibody broad-spectrum cocktail CP: Immunology CP: Microbiology omicron Prophylactics sarbecovirus SARS-CoV-2 [DOI] 10.1016/j.celrep.2022.111845 PMC 바로가기
Cross-reaction of current available SARS-CoV-2 MAbs against the pangolin-origin coronavirus GX/P2V/2017Article Published on 2022-12-132023-07-11 Journal: Cell Reports [Category] COVID19(2023년), [키워드] CP: Immunology CP: Microbiology immune difference monoclonal antibody pangolin CoVs. SARS-CoV-2 [DOI] 10.1016/j.celrep.2022.111831 PMC 바로가기
Interspecies recombination, not de novo mutation, maintains virulence after β-lactam resistance acquisition in Streptococcus pneumoniae종 간 재조합이 β-락탐 내성 획득 후 폐렴구균의 병원성을 유지한다, 새로운 돌연변이가 아니다.Article Published on 2022-12-132024-08-24 Journal: Cell Reports [Category] 폐렴구균 감염증, [키워드] Antibiotic resistance antibiotic tolerance CP: Microbiology fitness Horizontal gene transfer interspecies recombination pneumococci S. pneumoniae streptococci virulence β-lactam.
Molecular analysis of a public cross-neutralizing antibody response to SARS-CoV-2Article Published on 2022-11-152023-07-10 Journal: Cell Reports [Category] COVID19(2023년), [키워드] allelic preference broadly neutralizing COVID-19 CP: Immunology CP: Microbiology Data mining public antibody SARS-CoV-2 Sequence analysis variants of concern [DOI] 10.1016/j.celrep.2022.111650 PMC 바로가기
Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variantsArticle Published on 2022-11-012022-11-15 Journal: Cell Reports [Category] SARS, 변종, 진단, [키워드] Analysis antibodies antibody Beta breadth complementary conserved CP: Immunology CP: Microbiology Efficacy Hamster model human monoclonal antibodies immune Immune escape in vivo interact monoclonal antibody mutations neutralization neutralize Neutralizing activity omicron Omicron sublineages BA.1., BA.2, BA.2.12.1, and BA.4 overcome potent Protective provide raise reduced SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants Spike protein Spread the receptor-binding domain the SARS-CoV-2 therapeutic therapeutic antibodies therapeutic efficacy Vaccine variant variants variants of concern [DOI] 10.1016/j.celrep.2022.111528 PMC 바로가기
SARS-CoV-2 infects neurons and induces neuroinflammation in a non-human primate model of COVID-19Article Published on 2022-11-012022-11-15 Journal: Cell Reports [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] accompanied acute respiratory syndrome astrocytes Brain cellular mechanism CNS coronavirus coronavirus disease COVID-19 CP: Microbiology CP: Neuroscience Diabetic exacerbated High-resolution induce infect Infection initial investigated macaque microglia Microscopy modulated molecular Neuroinflammation Neurological complication Neurological complications Neuron neuronal neurotropism NHP non-human primate model olfactory patients plethora provide reducing Region rhesus rhesus. robust SARS-CoV-2 systemic inflammatory response triggered [DOI] 10.1016/j.celrep.2022.111573 PMC 바로가기
Reduced B cell antigenicity of Omicron lowers host serologic responseArticle Published on 2022-10-182022-11-15 Journal: Cell Reports [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Antibody Response Antibody titer antigenicity B cell Breakthrough infection common cold coronavirus computational structural biology conserved CP: Immunology CP: Microbiology cross-reactivity deep learning ELISA Epitopes evade explain feature geometric Host Infection less Lower mechanism Mice immunization experiment mutated Neutralizing omicron Omicron variant of concern RBD RBS Receptor binding Receptor binding domain receptor binding site reduced reduction reduction in reveal SARS-CoV-2 Serologic response serological response serum Spike protein trajectory vaccine-induced antibody variant variants viral evolution [DOI] 10.1016/j.celrep.2022.111512 PMC 바로가기
Bacillus subtilis programs the differentiation of intestinal secretory lineages to inhibit Salmonella infection바실러스 서브틸리스는 장 분비 계통의 분화를 조절하여 살모넬라 감염을 억제한다.Article Published on 2022-09-272024-08-22 Journal: Cell Reports [Category] 살모넬라증, [키워드] Bacillus subtilis CP: Microbiology differentiation intestinal epithelium. Notch pathway Salmonella Typhimurium
Essential role for epithelial HIF-mediated xenophagy in control of Salmonella infection and dissemination상피 HIF 매개 외래 식세포작용이 살모넬라 감염 및 전파 조절에 필수적인 역할Article Published on 2022-09-272024-08-22 Journal: Cell Reports [Category] 살모넬라증, [키워드] autophagy chromatin immunoprecipitation Colitis colonoid CP: Immunology CP: Microbiology hypoxia Inflammation Innate immunity mucosa neutrophil Transcription