Reverse Transcription-Loop-Mediated Isothermal Amplification-CRISPR-Cas13a Technology as a Promising Diagnostic Tool for SARS-CoV-2Article Published on 2022-10-262022-11-16 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome caused change clinical samples coronavirus coronavirus disease COVID-19 CRISPR-Ca CRISPR-Cas CRISPR-Cas13 cycle threshold deaths develop Diagnosis diagnostic Diagnostic method early diagnosis effort exhibit highlighting isothermal isothermal amplification maintain Molecular diagnosis nasopharyngeal sample Negative predictive value New coronavirus NPV pandemic performed persist Positive predictive value PPV Prevalence protocol reaction required researcher RNA extraction RNA molecules RT-LAMP SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus sensitivity Sensitivity and specificity single nucleotide single-stranded specificity technology viral loads [DOI] 10.1128/spectrum.02398-22 PMC 바로가기
Diagnostic efficiency of RT-LAMP integrated CRISPR-Cas technique for COVID-19: A systematic review and meta-analysisArticle Published on 2022-10-012022-11-15 Journal: Pathogens and global health [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] Accuracy applicability article calculated Care chain conducted confidence interval COVID-19 COVID-19 diagnosis COVID-19 pandemic CRISPR-Ca CRISPR-Cas database Diagnosis diagnostic Diagnostic method Efficiency eligibility criteria epidemiological equipment False-positive faster feasible forest plot isothermal amplification limit management Meta-analysis molecular N gene Precision problem QUADAS-2 Quantitative reaction Region regions resource reverse transcription RT-LAMP RT-qPCR SARS-CoV-2 sensitivity specificity systematic review Transcription USA was performed with COVID-19 [DOI] 10.1080/20477724.2022.2035625 PMC 바로가기
CRISPR-Cas system: from diagnostic tool to potential antiviral treatmentArticle Published on 2022-09-012022-11-15 Journal: Applied Microbiology and Biotechnology [Category] SARS, 치료기술, 치료제, [키워드] Antiviral treatment applied assays can be used clinical settings CRISPR-Ca CRISPR-Cas detect diagnose diagnosing Diagnosis diagnostic disease Diseases Effects HIV Influenza involved non-infectious offer overcome pathogen SARS-CoV-2 therapeutic Toxicity Treatment viral infection viral infections Virus Disease [DOI] 10.1007/s00253-022-12135-2 PMC 바로가기
CRISPR-based point-of-care diagnostics incorporating Cas9, Cas12, and Cas13 enzymes advanced for SARS-CoV-2 detectionSARS-CoV-2 검출을 위해 고급 Cas9, Cas12 및 Cas13 효소를 통합한 CRISPR 기반 현장 진료 진단Review Published on 2022-08-012022-09-11 Journal: Journal of biochemical and molecular toxicology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Beta beta coronavirus Cas12 Cas13 Cas9 Chain Reaction Characteristics clustered regularly interspaced short palindromic repeat Contamination coronavirus CRISPR CRISPR-Cas Diagnosis diagnostic Diagnostic strategies diagnostic system diagnostics disease disorder Efficiency enzyme global pandemic gold gold standard highlighting Intervention management Molecular diagnosis nucleic acid nucleic acids outbreak pathogen point-of-care Prognosis provide reagents Research respiratory Reverse transcription-polymerase chain reaction RPA RT-LAMP SARS-CoV-2 SARS-CoV-2 detection sensitivity Sensitivity and specificity Sickness simplicity specificity speed Spread Viral [DOI] 10.1002/jbt.23113 PMC 바로가기 [Article Type] Review
CRISPR-based systems for sensitive and rapid on-site COVID-19 diagnosticsReview article Published on 2022-06-082022-10-05 Journal: Trends in Biotechnology [Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘, 진단, 치료기술, [키워드] Cas12/13 costly COVID-19 COVID-19 diagnosis COVID-19 pandemic CRISPR-Ca CRISPR-Cas diagnostic capabilities diagnostics effective equipment evaluate Healthcare systems improvement inaccessible Infectious diseases isothermal amplification less medical intervention POC point-of-care Rapid test Research RNA/DNA detection RT-PCR sensitive sensitivity significantly strained Transmission [DOI] 10.1016/j.tibtech.2022.06.002 [Article Type] Review article
Palindromic target site identification in SARS-CoV-2, MERS-CoV and SARS-CoV-1 by adopting CRISPR-Cas techniqueArticle Published on 2022-04-152023-07-07 Journal: Gene [Category] COVID19(2023년), [키워드] CRISPR-Cas palindrome primer protospacer adjacent motif SARS-CoV-2 Target site identification. [DOI] 10.1016/j.gene.2021.146136 PMC 바로가기
Novel Assays for Molecular Detection of Severe Acute Respiratory Syndrome Coronavirus 2Review Published on 2022-03-092023-06-18 Journal: Clinics in laboratory medicine [Category] COVID19(2023년), MERS, SARS, [키워드] COVID-19 CRISPR-Cas Microfluidics molecular Next-generation sequencing SARS-CoV-2 variant [DOI] 10.1016/j.cll.2022.02.004 PMC 바로가기 [Article Type] Review
Therapeutic potentials of CRISPR-Cas genome editing technology in human viral infectionsReview Published on 2022-02-252023-06-03 Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] B형 간염, COVID19(2023년), MERS, SARS, [키워드] CRISPR-Cas gene editing Infection Treatment virus [DOI] 10.1016/j.biopha.2022.112743 PMC 바로가기 [Article Type] Review
Recent Advances and Future Directions in the Understanding of Mucormycosis점막염에 대한 이해의 최근 발전과 향후 방향Review Published on 2022-02-242022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, 유전자 메커니즘, 진단, [키워드] acquired resistance advance Analysis antifungal resistance caused characterization COVID-19 patient CRISPR CRISPR-Cas CRISPR-Cas9 Diagnosis direction effective expected Factor fungal fungi Future genetic manipulation genetic model genomic in some incidence Infection intractable involved knowledge macrophages molecular mechanism molecular mechanisms Mucorale Mucorales Mucormycosis Pathogenesis phagocytosis recent reduced the disease Treatment understanding virulence virulence factors whole genome sequence [DOI] 10.3389/fcimb.2022.850581 PMC 바로가기 [Article Type] Review
Delivery of CRISPR-Cas tools for in vivo genome editing therapy: Trends and challengesReview article Published on 2022-02-012022-10-05 Journal: Journal of controlled release : official journal o [Category] 비임상, [키워드] AAV approach caused clinical trial clinical trials component CRISPR CRISPR-Ca CRISPR-Cas delivery Diseases effective Gene therapy Genome genomic integration High dose highlight in vivo limitations Lipid nanoparticle liver LNP Mutagenesis overcome palindromic repeat Safe shown therapy Toxicity trend virus Virus-like particle VLP [DOI] 10.1016/j.jconrel.2022.01.013 [Article Type] Review article