COVID-19-associated Cryptococcus infection (CACI): a review of literature and clinical pearlsBrief Report Published on 2022-03-242023-06-18 Journal: Infection [Category] MERS, [키워드] COVID-19 Cryptococcus fungus immunosuppressive opportunistic Infections [DOI] 10.1007/s15010-022-01805-y PMC 바로가기 [Article Type] Brief Report
Cryptococcal Protease(s) and the Activation of SARS-CoV-2 Spike (S) ProteinArticle Published on 2022-01-272022-10-31 Journal: Cells [Category] COVID-19, [키워드] Cryptococcus neoformans activate biochemical cleavage site comparable cryptococcal infection Cryptococcus Efficiency fluorogenic peptide furin Infection peptide protease Protein proteolytic cleavage PRRA S protein S1 and S2 S1/S2 cleavage site S1/S2 site SARS-CoV-2 SARS-CoV-2 disease sequence spike spike (S) protein the SARS-CoV-2 unique [DOI] 10.3390/cells11030437 PMC 바로가기 [Article Type] Article
Pulmonary aspergillosis and cryptococcosis as a complication of COVID-19Case Report Published on 2022-01-062022-10-29 Journal: Medical Mycology Case Reports [Category] COVID-19, [키워드] Aspergillus Bronchoalveolar lavage CAPA Comorbidities Comorbidity complicate complication of COVID-19 Corticosteroid COVID-19 Critical Cryptococcus Culture Cyclophosphamide diagnosed dose Fungal infection High-dose hospital hypoxic respiratory failure immunosuppressants Infection morbidity and mortality Patient pulmonary aspergillosis SARS-CoV-2 Secondary infection transferred Treatment worsening [DOI] 10.1016/j.mmcr.2022.01.003 PMC 바로가기 [Article Type] Case Report
Dynamic genome plasticity during unisexual reproduction in the human fungal pathogen Cryptococcus deneoformans인간 곰팡이 병원체 암호화 코커스 데네 노모 인에서의 단성 재생산 동안의 동적 게놈 소성Research Article Published on 2021-11-292022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] adaptation addition Aneuploidy azole Cancer Cell cell cycle cell-cell fusion cells characterization characterized chromosome chromosomes concert conditions contributed copy number Critical Cryptococcus Cryptococcus neoforman Cryptococcus neoformans cyclin cyclins defect detect differentially expressed diploid duplication dynamic early phase eukaryotic events Evidence evidence of Evolution example form fungal fungi generate genes encoding Genetic Genome hallmark haploid Host host infection Implications in some increase independent instance intrinsic isolates kinase kinases lead maintain maintenance mechanism meiosis meiotic mitotic molecular mechanism molecular mechanisms nourseothricin nuclear nuclear fusion occur organism Organisms pathogen pathway plasticity ploidy polyploid public health Regulatory reporter serotype sexual development survival uracil VAR Variation [DOI] 10.1371/journal.pgen.1009935 PMC 바로가기 [Article Type] Research Article
Disseminated Cryptococcus neoformans infection associated to COVID-19Case Report Published on 2021-10-222022-10-29 Journal: Medical Mycology Case Reports [Category] COVID-19, [키워드] coronavirus 2 Corticosteroid Corticosteroids COVID-19 Cryptococcus Cryptococcus neoformans drug Fungal infection High dose immune dysregulation Immunosuppression increase Infection Novel coronavirus opportunistic Infections Organizing pneumonia Patient respiratory risk SARS-CoV-2 severe COVID-19 Treatment [DOI] 10.1016/j.mmcr.2021.10.001 PMC 바로가기 [Article Type] Case Report
The Possible Role of Microbial Proteases in Facilitating SARS-CoV-2 Brain InvasionOpinion Published on 2021-09-272022-10-28 Journal: Biology [Category] COVID-19, [키워드] ACE2 activate Angiotensin-converting enzyme Brain Cell cells Co-infection Cryptococcus Endothelial cell expression facilitate Facilitating fungal glycoprotein information instance Intervention Invasion Measures mechanism membrane fusion microbe microbial neurotropism organ Pathogens protease role S2 domain SARS-CoV-2 secretion shown simple understanding viral spike virus [DOI] 10.3390/biology10100966 PMC 바로가기 [Article Type] Opinion
Overview on the Prevalence of Fungal Infections, Immune Response, and Microbiome Role in COVID-19 PatientsReview Published on 2021-09-022022-10-30 Journal: Journal of Fungi [Category] COVID-19, [키워드] Mucor Analysis Aspergillus Awareness Bacterial Candida Co-infection COVID-19 COVID-19 patients Cryptococcus death described Diagnosis fungal fungal disease Fungal infection fungal infections high risk Histoplasma Host immune response ICU immune response incidence increasingly individual Infection infections intensive care unit Microbiome Mucor Occurrence outcome patients prevalent response Rhizopus rising role SARS-CoV-2 severe COVID-19 Support susceptible Treatment was performed [DOI] 10.3390/jof7090720 PMC 바로가기 [Article Type] Review
Cryptococcus neoformans Meningoencephalitis in an Immunocompetent Patient after COVID-19 InfectionCase Report Published on 2021-06-042022-10-31 Journal: Case Reports in Infectious Diseases [Category] COVID-19, [키워드] Bacterial cause COVID-19 COVID-19 pandemic Cryptococcus Cryptococcus neoforman Dexamethasone evaluate the effect Fungal infection healthy hosts immune system Immunocompromised Infection infectious complication knowledge lymphopenia Meningitis meningoencephalitis opportunistic Infections pathogen Patient reported saprophytic SARS-COV-2 infection T-cell Treatment while [DOI] 10.1155/2021/5597473 PMC 바로가기 [Article Type] Case Report
Pleiotropy and epistasis within and between signaling pathways defines the genetic architecture of fungal virulence신호 전달 경로 내 및 사이의 다면발광 및 상위성은 진균 독성의 유전적 구조를 정의합니다Research Article Published on 2021-01-252022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Affect amphotericin B Analysis antifungal drug resistance approach Author avirulent body temperature CAMP cascade Cell Cell signaling cellular cellular response Cellular responses characterization Combination complex component contribute cross Cryptococcal disease Cryptococcus cyclic AMP disease drug susceptibility drugs ENCODE epistatic interaction Europe Extracellular fungal Genes Genetic genetic architecture genetic difference genetic differences Genetic variation glycerol growth highlight human body Infection information isolate kinase Lineage locus make up mapping microbial modify molecular nucleotide osmolarity osmotic oxidative oxidative stress oxidative stress resistance pathogen pathogenicity Pathogens pathway phenotypic phenotypic variation physiological response pleiotropic polysaccharide capsule progeny promote protein kinase QTL Quantitative quantitative trait locus regulate regulator sensitivity Signal transduction Signaling signaling pathway strain Strains Stress temperate climates thought Tolerance traits underlie Variation virulence virulent [DOI] 10.1371/journal.pgen.1009313 PMC 바로가기 [Article Type] Research Article
Factors enforcing the species boundary between the human pathogens Cryptococcus neoformans and Cryptococcus deneoformans인간 병원체 크립토코커스 네오포르만스와 크립토코커스 데네오포르만스 사이의 종 경계를 강화하는 요인Research Article Published on 2021-01-192022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Alternative pathway Aneuploidy Bacterial block component Cryptococcus Cryptococcus neoforman Cryptococcus neoformans deleting determine DNA DNA sequence DNA sequences eukaryote eukaryotes Factor fecundity Frequency fungal Genetic genetic recombination human pathogen hybrid hybridization identify increase in incubated instance interspecific interspecific hybrid interspecific hybrids isolate lack lead limit Loss maintain mechanism medium meiosis meiotic recombination Msh2 parent parental parents pathogenic pathway phenotype Previous studies previous study produced progeny Recombination Sequencing sexual reproduction strain Structure structures transgressive phenotype transgressive phenotypes unique Variation viability whole-genome whole-genome sequencing yeast [DOI] 10.1371/journal.pgen.1008871 PMC 바로가기 [Article Type] Research Article