Case report: SARS-CoV-2 infection as a trigger for diabetic ketoacidosis and newly detected pancreatic autoantibodiesArticle Published on 2022-08-102022-11-15 Journal: Frontiers in Endocrinology [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome Altered mental status antibody autoantibodies autoantibody autoimminity beta-hydroxybutyrate blood glucose collected coronavirus CoV COVID COVID – 19 diabete Diabetes Mellitus Diabetic diagnosed Diagnosis discharged home Follow-up increased risk Infection infection with SARS-CoV-2 insulin nausea pancreatic past medical history positive regimen SARS – CoV – 2 SARS-CoV-2 SARS-COV-2 infection Shortness of breath T1D type 1 diabetes (T1D). type 2 diabete vomiting [DOI] 10.3389/fendo.2022.983206 PMC 바로가기
A case of Bacillus subtilis var. natto bacteremia caused by ingestion of natto during COVID-19 treatment in a maintenance hemodialysis patient with multiple myelomaCase report Published on 2022-08-012022-10-05 Journal: Journal of infection and chemotherapy : official j [Category] 변종, 치료법, [키워드] acute respiratory syndrome Admission age association B. subtilis Bacillus subtilis Bacteremia Bacteria Bacterial Blood caused conditions coronavirus coronavirus disease COVID-19 Critical Culture cultures Diabetes Mellitus Diabetic diagnosed during treatment End-stage renal disease Hemodialysis hospital Immunocompromised immunosuppressive ingestion intestinal inflammation intestinal permeability malignant tumor Multiple myeloma nephropathy next-generation sequencer Patient risk steroid symptomatic the patient therapy Tocilizumab translocation treated Treatment vancomycin VAR [DOI] 10.1016/j.jiac.2022.05.006 [Article Type] Case report
SARS-CoV-2 infection impairs the insulin/IGF signaling pathway in the lung, liver, adipose tissue, and pancreatic cells via IRF1SARS-CoV-2 감염은 IRF1을 통해 폐, 간, 지방 조직 및 췌장 세포의 인슐린/IGF 신호 전달 경로를 손상시킵니다Article Published on 2022-08-012022-09-11 Journal: Metabolism: clinical and experimental [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] Activation adeno-associated virus adipose Adipose tissue AKT ameliorated analyzed association Autopsy Calu3 Calu3 cell CaLu3 cells Cell cell survival cells condition contribute COVID-19 COVID-19 pathology COVID-19 patient COVID-19 patients COVID-19 severity Critical critical patient critical patients cytokine determine Dexamethasone diabetes Diabetic diabetic patients Dihydrotestosterone Endocrine energy metabolism European population evaluate Evidence exacerbated exhibited Gain Gene Expression Genes GFP HEK293T Hospitalized Host human ACE2 human cells hyperglycemia impair impairment infected with SARS-CoV-2 insulin insulin resistance Insulin signaling Insulin/IGF signaling pathway interferon regulatory factor Interferone intron IRF1 liver lung Lungs male Male sex MAPK metabolic metabolic abnormalities Metabolic abnormality metabolism mouse model mTOR Multiorgan dysfunction Multiple organ damage Non-COVID-19 Non-COVID-19 patients obese obesity Older Older age Organoid overexpressing pancreatic Pancreatic cell pancreatic islets pathology patients patients with COVID-19 PI3K potential mechanism Prevalence provide Regulation reported Repository risk factor Risk factors SARS-CoV-2 SARS-CoV-2 infected cell SARS-CoV-2 infected cells SARS-COV-2 infection serotype severe COVID-19 severity Signaling signaling pathway significantly stem cell survival tissue tissue damage Tissue damage. tissues Transcriptome transcriptome dataset transcriptome datasets Transgenic mouse variant Whole blood whole blood transcriptome with COVID-19 [DOI] 10.1016/j.metabol.2022.155236 PMC 바로가기 [Article Type] Article
Symptoms and Glycemic Control in Young People With Type 1 Diabetes Following SARS-CoV-2 Infection: An Observational StudyObservational Study Published on 2022-07-142022-10-05 Journal: The Journal of Clinical Endocrinology and Metaboli [Category] COVID19(2023년), SARS, 임상, [키워드] 95% CI Adults age analyzed Asymptomatic asymptomatic infection children clinical manifestation clinical symptom clinics Cohort collected Comorbidity conducted Control Course COVID-19 COVID-19 infection Deterioration diabete diabetes Diabetic disease course DKA Effect elevated fatigue Fever Glucose glycemic control Headaches help Hospitalization identifying immunodeficiency Infection management measure median Mild occurred Odds ratio Older age outcomes Patient patients pediatric persistent polymerase chain positive prolonged disease Quantitative questionnaire regression analysis reported required SARS-CoV-2 SARS-COV-2 infection sense of smell sick Symptom symptomatic infection Symptoms syndrome T1D tested the disease Type type 1 diabetes. [DOI] 10.1210/clinem/dgac288 PMC 바로가기 [Article Type] Observational Study
The molecular and metabolic landscape of iron and ferroptosis in cardiovascular disease Reviews Published on 2022-07-042022-10-05 Journal: Nature reviews. Cardiology [Category] 바이오마커, 변종, [키워드] arrhythmia Atherosclerosis cardiac function Cardiomyopathy cardiovascular disease cardiovascular diseases Diabetic disease Evidence Ferroptosis heart failure improvement increasingly Injury involved iron homeostasis limitation management mechanism metabolism molecular Myocardial Pathogenesis pathway progression Regulated cell death Regulation review subtype target targets Treatment [DOI] 10.1038/s41569-022-00735-4 [Article Type] Reviews
Rotational thromboelastometry in patients with type 2 diabetes and mild COVID-19 pneumonia: A pilot prospective studyObservational Study Published on 2022-07-012022-10-05 Journal: Medicine [Category] 임상, [키워드] Blood donors blood sample changes in complex consecutive patient control group COVID-19 demonstrated diabete Diabetic enrolled healthy healthy donors Hemostasis higher risk Mild no significant difference not affected parameter Patient performed Pneumonia Prospective Study reagents Severe COVID-19 pneumonia significant difference T2D tested thromboembolic complications type 2 diabete Whole blood [DOI] 10.1097/MD.0000000000029738 PMC 바로가기 [Article Type] Observational Study
Safety considerations of chloroquine in the treatment of patients with diabetes and COVID-19Research article Published on 2022-07-012022-10-05 Journal: Chemico-biological interactions [Category] COVID19(2023년), SARS, 신약개발, 치료법, 치료제, [키워드] adverse effect Cardiotoxicity caused changed Chloroquine Chloroquine phosphate coronavirus disease COVID-19 death diabetes Diabetic dosage dose Drug safety effective Electrocardiograms elevated hepatic enzyme High dose High-dose high-dose group humans IL-1β IL-6 levels increased risk intervals kidneys leukocyte liver observation Ocular toxicity Patient patients with diabete produced Protein QTc regimen Safety serum Severe case significantly spleen T2D total mortality treat Treatment type 2 diabete underlying disease [DOI] 10.1016/j.cbi.2022.109954 [Article Type] Research article
Gene Networks of Hyperglycemia, Diabetic Complications, and Human Proteins Targeted by SARS-CoV-2: What Is the Molecular Basis for Comorbidity?SARS-CoV-2가 표적으로 하는 고혈당증, 당뇨병 합병증 및 인간 단백질의 유전자 네트워크: 동반 질환의 분자적 근거는 무엇입니까?Article Published on 2022-06-292022-09-11 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘, [키워드] ACE2 ANDSystem Angiogenesis applied approach associative Basis Beta beta cell Beta cells bioinformatics Bioinformatics analysis BRD2 Cell Comorbidity Complication complications COMT COVID-19 CTSB CTSL defined degranulation determine diabete diabetes Diabetic diabetic complications disorder DNMT1 DPP4 dysfunction enrichment analysis ERP44 expand F2RL1 GDF15 gene networks Gene ontology General population GPX1 HDAC2 HMOX1 Human HYOU1 hyperglycemia hypoxia IDE identify immune Inflammatory response insulin insulin resistance insulin resistance. intracellular protein involved LOX mechanism metabolism molecular basis molecular network network NUTF2 organ damage oxygen pathophysiological patients with diabetes PCNT PLAT Platelet protease Proteins RAB10 reactive oxygen specy reconstructed Regulation RHOA SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 entry receptor SCARB1 SELENOS severe COVID-19 TMPRSS2 Vascular [DOI] 10.3390/ijms23137247 PMC 바로가기 [Article Type] Article
Bilateral Emphysematous Pyelonephritis Associated with COVID Pneumonia: A Case ReportCOVID 폐렴과 관련된 양측 폐기종성 신우신염: 증례 보고Case Reports Published on 2022-06-272022-09-11 Journal: The American journal of case reports [Category] Coronavirus, COVID19(2023년), SARS, 치료기술, [키워드] ACE2 acute respiratory distress acute respiratory distress syndrome angiotensin Angiotensin-converting enzyme Antimicrobial therapy Bilateral caused Cell cells changes in Combination Coronavirus infection COVID COVID-19 COVID-19 infection Diabetic Diagnosis Emergency Emphysematous emphysematous pyelonephritis Fever general condition human cell human cells Inflammation inflammatory change inflammatory changes inflammatory process Injury kidneys linkage local inflammation lung parenchyma movement nephrectomy outcome Pain parenchymal Pneumonia potentiation progressed pyelonephritis receptor renal renal abnormalities renal abnormality report respiratory distress respiratory symptoms risk factor SARS-CoV-2 SARS-CoV-2 virus Sepsis shivering symptomatic syndrome the patient the SARS-CoV-2 virus therapy treat Treatment tubular cell Urinary tract Viral pneumonia worse prognosis [DOI] 10.12659/AJCR.936370 PMC 바로가기 [Article Type] Case Reports
A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells당뇨병 환경은 인간 신장 오르가노이드 및 환자 세포에서 SARS-CoV-2 감염에 대한 ACE2 발현 및 세포 감수성을 증가시킵니다Article Published on 2022-06-072022-09-11 Journal: Cell Metabolism [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] ACE2 ACE2 expression aerobic aerobic glycolysis angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 biopsy Cell cells cellular condition COVID-19 COVID-19 pathogenesis Critical develop diabete diabetes diabetes 2 Diabetic diabetic kidney diabetic patient diabetic patients dichloroacetate door energy metabolism enzyme exhibited Glycolysis hallmark human kidney human kidney organoids. increase individual inhibitor Intervention kidney Kidney disease kidney organoid kidney organoids metabolism mitochondrial Organoid organoids Patient prevented programming reduced resulting SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections severe COVID-19 susceptibility Viral detection Viral load [DOI] 10.1016/j.cmet.2022.04.009 PMC 바로가기 [Article Type] Article