Infection and transmission of ancestral SARS-CoV-2 and its alpha variant in pregnant white-tailed deer임신한 흰꼬리사슴에서 조상 SARS-CoV-2 및 그 알파 변이체의 감염 및 전파Coronaviruses Published on 2021-12-212022-09-10 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] addition Alpha Alpha variant Alpha VOC B.1.1.7 B.1.1.7 isolate cervid circulating Co-infection competition Contact coronavirus deer demonstrated determine direct contact evidence of examined fetus Genome global pandemic Host human population human populations in silico in viral in vitro study indicated Infection intermediate hosts investigated Lineage nasal natural infection Next-generation sequencing oral cavities outbreak Pregnancy pregnant recent reported SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 isolates SARS-like coronavirus Sequencing shown susceptibility susceptible tissue tissues Transmission transmission of SARS-CoV-2 variant variety Viral virus VoC was used white-tailed deer widespread [DOI] 10.1080/22221751.2021.2012528 PMC 바로가기 [Article Type] Coronaviruses
Infection of wild-type mice by SARS-CoV-2 B.1.351 variant indicates a possible novel cross-species transmission routeSARS-CoV-2 B.1.351 변이체에 의한 야생형 마우스 감염은 가능한 새로운 종간 전파 경로를 나타냅니다Article Published on 2021-12-142022-09-10 Journal: Signal Transduction and Targeted Therapy [Category] Fulltext, SARS, 바이오마커, 변종, 유전자 메커니즘, [키워드] accompanied addition angiotensin angiotensin-converting enzyme 2 animal model antiviral inhibitor antiviral inhibitors B.1.351 binding affinity caused Contact COVID-19 COVID-19 pathogenesis Cross-species transmission Cytokines direct contact elevated enzyme Epidemic evaluate expand expressed Genetic modifications host range human population human populations increase indicate Infection Infectious diseases lung Lungs mACE2 mice Modification Mutation pathological change Proinflammatory cytokine proinflammatory cytokines RBD Receptor-binding domain regulated replicated SARS-CoV-2 SARS-CoV-2 B.1.351 variant SARS-CoV-2 variant sera Spike protein strain susceptible the receptor-binding domain the SARS-CoV-2 tracheas Transmission transmission of SARS-CoV-2 Vaccines variant Viral viral infection wild-type zoonotic disease [DOI] 10.1038/s41392-021-00848-1 PMC 바로가기 [Article Type] Article
Enhancement of Antiviral Effect of Plastic Film against SARS-CoV-2: Combining Nanomaterials and Nanopatterns with Scalability for Mass ManufacturingSARS-CoV-2에 대한 플라스틱 필름의 항바이러스 효과 향상: 대량 생산을 위한 확장성과 나노 물질 및 나노 패턴의 결합Letter Published on 2021-12-092022-09-10 Journal: Nano Letters [Category] SARS, 치료제, [키워드] Antiviral Concentration Contact contact with contaminated surface contaminated surfaces COVID-19 Direct direct contact Effect Effectiveness ENhance enhancement film integration issue likelihood magnitude mass Nanomaterial nanomaterials nanostructure plastic reducing Result SARS-CoV-2 scalability scalable production shape spacing the SARS-CoV-2 thermal nanoimprinting lithography Transmission ultrasonic atomization spray coating virus [DOI] 10.1021/acs.nanolett.1c02266 PMC 바로가기 [Article Type] Letter
Single-Cell Immunogenomic Approach Identified SARS-CoV-2 Protective Immune Signatures in Asymptomatic Direct Contacts of COVID-19 CasesCOVID-19 사례의 무증상 직접 접촉에서 SARS-CoV-2 보호 면역 서명을 식별한 단일 세포 면역유전체학적 접근 방식Immunology Published on 2021-11-252022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 유전자 메커니즘, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adaptive immune response amplitude antibody Antibody titer Asymptomatic B-cell BCR CD4 CD8 Cell characterized class close contact colony stimulating factor concomitant increase Contact controls coronavirus coronavirus disease Coronavirus disease 2019 CoV COVID-19 cytokine cytokine levels Cytokines direct contact Direct Contacts Eotaxin G-CSF granulocyte granulocyte-colony stimulating factor host immunity Identified IL-7 impacted infected cases infected patients Inflammatory inhibitory interleukin Macrophage memory memory B cell memory B cells MIF Migration MIP-1α naïve T cells Neutralizing Patient patients Profiling proportion receptor reported respiratory RNA SARS-CoV-2 scBCR-seq scRNA-seq scTCR-seq Sequencing severe acute respiratory syndrome Coronavirus shown signature significant increase single-cell status T cell T cells T-cell receptor TCR Temra cells virus Virus neutralization [DOI] 10.3389/fimmu.2021.733539 PMC 바로가기 [Article Type] Immunology
Pediatric home confinement due to COVID-19: Somatic and anxiety spectrum consequencesCOVID-19로 인한 소아과 자택 감금: 신체 및 불안 스펙트럼 결과Observational Study Published on 2021-11-012022-09-11 Journal: Journal of clinical nursing [Category] SARS, 임상, 치료기술, [키워드] activities activity affected age Anxiety anxiety symptom behavioural changes children Clinical practice communicable communicable diseases conducted confinement consequence COVID-19 COVID-19 outbreak COVID-19 pandemic cross-sectional detect determine direct contact emotional Government impacted infected with COVID-19 Infection Intervention involved Isolation limit lockdown Manifestations Mental mental health number of symptom Nurse Nurses Nursing observational study on children pandemic parent parents participant Prevent problem questionnaire Relevance reported researchers restlessness scale scored Somatic Spain Spread suffered Symptom Symptoms Total [DOI] 10.1111/jocn.15829 PMC 바로가기 [Article Type] Observational Study
SARS-CoV-2 and Public Transport in Italy이탈리아의 SARS-CoV-2 및 대중 교통Article Published on 2021-10-292022-09-10 Journal: International Journal of Environmental Research an [Category] MERS, SARS, 치료기술, [키워드] analyzed Contact contaminated surface COVID-19 direct contact environmental factor environmental factors evaluated FIVE followed by greater highlight Italy limit positive sample Public public transport SARS-CoV-2 Spread surfaces tested transmission of SARS-CoV-2 Transport virus [DOI] 10.3390/ijerph182111415 PMC 바로가기 [Article Type] Article
Structure-Function Analysis of Resistance to Bamlanivimab by SARS-CoV-2 Variants Kappa, Delta, and LambdaSARS-CoV-2 변이체 카파, 델타 및 람다에 의한 밤라니비맙 내성의 구조-기능 분석Article Published on 2021-10-252022-09-11 Journal: Journal of Chemical Information and Modeling [Category] SARS, 변종, [키워드] ACE2 Affect angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 antibodies antibody bamlanivimab binding binding affinity carried characterized Contact contact with crystal structures Delta demonstrated direct contact Effects evade experiment host cells L452R Lambda LY-CoV555 molecular molecular dynamics molecular mechanism mutant Mutation Neutralization assay neutralization assays Neutralizing Neutralizing activity Patient pseudovirions RBD RBDs Receptor binding domain receptor binding domains reduce residue resistance SARS-CoV-2 SARS-CoV-2 variant significantly Spike proteins the binding affinity the RBD therapeutic Treatment variant variants viral entry wild-type SARS-CoV-2 [DOI] 10.1021/acs.jcim.1c01058 PMC 바로가기 [Article Type] Article
Partial protection of Sinopharm vaccine against SARS COV2 during recent outbreak in Bahrain최근 바레인에서 발생한 SARS COV2에 대한 Sinopharm 백신의 부분적 보호Article Published on 2021-09-012022-09-11 Journal: Microbial pathogenesis [Category] SARS, 치료기술, [키워드] Bahrain case study chest pain Community complications Contact contact with cooperation Council country Deceased detect determine diabetes Diabetes Mellitus direct contact dose Efficacy GCC Gulf headache Hospitalization Hospitalized Immunity Infection infections lack lung Lung infection Mild outbreak Partial Protein protein structure provide provided recipient S protein SARS CoV SARS CoV 2 single dose Sinopharm Transmission vaccination Vaccinations Vaccine Vaccines Variation virus were infected WHO WHO. [DOI] 10.1016/j.micpath.2021.105086 PMC 바로가기 [Article Type] Article
Intranasal ChAdOx1 nCoV-19/AZD1222 vaccination reduces viral shedding after SARS-CoV-2 D614G challenge in preclinical models비강 내 ChAdOx1 nCoV-19/AZD1222 백신 접종은 전임상 모델에서 SARS-CoV-2 D614G 공격 후 바이러스 발산을 감소시킵니다Article Published on 2021-08-182022-09-11 Journal: Science Translational Medicine [Category] SARS, 진단, 치료기술, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adenovirus-based Administered animal models approved Bronchoalveolar lavage ChAdOx1 ChAdOx1 nCoV-19 Contact contact with coronavirus COVID-19 vaccines D614G mutation did not reduce direct contact hamster hamsters Infectious virus intramuscular vaccination intranasally investigated Lower respiratory tract lung tissue macaque nasal swab nasal swabs Pneumonia Previous studies previous study provided reduce reduced reduction in rhesus macaque rhesus macaques SARS-CoV-2 SARS-CoV-2 D614G severe acute respiratory syndrome Coronavirus shedding Spike protein Swab swabs the spike protein tissue upper respiratory tract vaccination Vaccine Viral load viral loads Viral RNA viral shedding virus virus concentration [DOI] 10.1126/scitranslmed.abh0755 PMC 바로가기 [Article Type] Article
Coronavirus Disease 2019 (COVID-19) Seropositivity and Asymptomatic Rates in Healthcare Workers Are Associated with Job Function and Masking코로나바이러스 질병 2019(COVID-19) 의료 종사자의 혈청 양성 및 무증상 비율은 직무 및 마스킹과 관련이 있습니다Article Published on 2021-07-302022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome coronavirus anti-SARS-CoV-2 IgG antibody Asymptomatic Asymptomatic individuals blood collection blood sample Contact contact with coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 detection Determining Detroit Direct direct contact Donor equipment Euroimmun exhibited exposure to foundation frontline healthcare workers function healthcare Healthcare workers hospital include infection rate information Isolation job less likelihood limit limits Mask masking Masks participant Patient phlebotomy positive proportion Protective Rate reported respiratory respiratory therapy risk SARS-CoV-2 seropositive seropositive individuals Seropositivity severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly higher significantly lower study participant Study participants Support therapy virus was collected was determined with COVID-19 worker [DOI] 10.1093/cid/ciaa1684 PMC 바로가기 [Article Type] Article