Multi-species single-cell transcriptomic analysis of ocular compartment regulonsArticle Published on 2021-09-282022-10-04 Journal: Nature Communications [Category] 유전자 메커니즘, [키워드] addition adult stem cells Cell cell types ciliary comprehensive analysis directional disease disorder Factors ganglion cell ganglion cells Gene Expression Gene regulation Health identify include Interaction involved KLF7 maturation neural retina ocular populations probe Research Retina single-cell Single-cell RNA sequencing single-cell transcriptomic analysis stem cell tissue transcription factor transcriptomic transcriptomics unique various tissue Vertebrate zebrafish [DOI] 10.1038/s41467-021-25968-8 PMC 바로가기 [Article Type] Article
Mutational spectrum of SARS-CoV-2 during the global pandemic세계적 대유행 동안 SARS-CoV-2의 돌연변이 스펙트럼Article Published on 2021-08-272022-09-10 Journal: Experimental & Molecular Medicine [Category] MERS, SARS, 변종, [키워드] accumulate Analysis Asia base collected collection time coronavirus COVID-19 pandemic cytosine directional ENhance equilibrium Evidence evidence of Evolution Evolutionary biology exhibit extreme genetic material Genome Genome evolution genome sequence global pandemic guanine help human population information interactions monitoring much higher Mutation mutational processe mutational processes mutational spectrum natural selection nucleic acid predict reached replaced REPLACED BY researcher responsible SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 mutations SARS-CoV-2 viral infection SARS-CoV-2 virus Science sequence South Korea Spectrum substitutions technology the SARS-CoV-2 genome the SARS-CoV-2 virus Transmission uracil Viral viral genes viral genome sequence viral genome sequences viral infection Viral transmission virus viruses was performed [DOI] 10.1038/s12276-021-00658-z PMC 바로가기 [Article Type] Article
Preventive behaviours and family inequalities during the COVID-19 pandemic: a cross-sectional study in ChinaResearch Article Published on 2021-07-202022-10-29 Journal: Infectious Diseases of Poverty [Category] COVID-19, SARS, [키워드] 95% CI Abstract affected age Analysis China conducted coronavirus disease COVID-19 Critical cross-sectional Data analysis directional Diseases eight ENhance expand Factor FIVE Government group groups Hierarchical household inequality information inhibiting effect international public health knowledge Mantel–Haenszel media Older older adult pandemic participant Perspective platform Population preventive behaviours preventive measures public health questionnaire Research Result stratified Support Symptom variables was used were used women [DOI] 10.1186/s40249-021-00884-7 PMC 바로가기 [Article Type] Research Article
The effect of COVID19 pandemic restrictions on an urban rodent population도시 설치류 인구에 대한 COVID19 전염병 제한의 영향Article Published on 2021-06-212022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 치료기술, [키워드] absence affected binary data capture captures changes in city collected COVID-19 COVID19 declined defined directional driven by Effect Frequency geographical distribution Government health authorities implication Invasive species Local local government lockdown management measure pandemic Population Population dynamics populations presence or absence public health authorities public health authority rapid increase RATs Relocation reported resource resources rodent rodents spread of COVID-19 Urban ecology [DOI] 10.1038/s41598-021-92301-0 PMC 바로가기 [Article Type] Article
Permethrin resistance in Aedes aegypti : Genomic variants that confer knockdown resistance, recovery, and deathAedes Aegypti의 퍼메 트린 저항 : 녹다운 저항, 회복 및 사망을 부여하는 게놈 변이체Research Article Published on 2021-06-172022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Aede Amino acid amino acid substitution amino acid substitutions association calcium calcium channel Chikungunya comparison Concentration cuticle dead death Dengue dependent on detoxification detoxification enzymes develop directional disease disease control disease outbreaks effective Frequency functional Genes genetic background Genome genomic genomic variant genomic variants heterogeneous population identify IMPROVE individual information insecticide insecticides knockdown knockdown resistance lead list marker mechanism metabolism moderate Mosquito Mutation occur Outbreaks penetration performed Permethrin phenotype phenotypic polymorphism Population populations Prevent proportion protein coding genes Proteins provide public health pyrethroid Pyrethroids reduce Region resistance mechanism resistance mechanisms response sequenced single-nucleotide Single-nucleotide polymorphisms SNPs sodium sodium channel suppress suppression survival tested transmitted Treatment Vaccine variant vector control viral disease Viral diseases voltage voltage-gated sodium channel Zika Zika viruses [DOI] 10.1371/journal.pgen.1009606 PMC 바로가기 [Article Type] Research Article
Lung Infection Segmentation for COVID-19 Pneumonia Based on a Cascade Convolutional Network from CT ImagesResearch Article Published on 2021-04-152022-10-27 Journal: BioMed Research International [Category] COVID-19, MERS, SARS, [키워드] Accuracy approach ASD average caused Clustering CNN complex country COVID-19 COVID-19 infection COVID-19 pandemic demonstrated diagnose directional disease feature female healthcare Image impacts infections Local local public health lung CT scan Lung infection male National network offer outbreak overcome overfitting overlap patients Precision problem recall Region Segmentation the patient tissue tissues Treatment Volume [DOI] 10.1155/2021/5544742 PMC 바로가기 [Article Type] Research Article
Lung Infection Segmentation for COVID-19 Pneumonia Based on a Cascade Convolutional Network from CT ImagesCT 이미지의 캐스케이드 컨볼루션 네트워크를 기반으로 하는 COVID-19 폐렴에 대한 폐 감염 세분화Research Article Published on 2021-04-152022-09-10 Journal: BioMed Research International [Category] 치료기술, [키워드] Accuracy approach ASD average caused Clustering CNN complex Convolutional neural network country COVID-19 COVID-19 infection COVID-19 pandemic demonstrated diagnose directional disease F score feature female healthcare Image impacts infections Local local public health lung CT scan Lung infection male National network offer outbreak overcome overfitting overlap patients Precision problem recall Region Segmentation the patient tissue tissues Treatment Volume [DOI] 10.1155/2021/5544742 PMC 바로가기 [Article Type] Research Article
Lung Infection Segmentation for COVID-19 Pneumonia Based on a Cascade Convolutional Network from CT ImagesResearch Article Published on 2021-04-152022-10-27 Journal: BioMed Research International [Category] [키워드] Accuracy approach ASD average caused Clustering CNN complex country COVID-19 COVID-19 infection COVID-19 pandemic demonstrated diagnose directional disease feature female healthcare Image impacts infections Local local public health lung CT scan Lung infection male National network offer outbreak overcome overfitting overlap patients Precision problem recall Region Segmentation the patient tissue tissues Treatment Volume [DOI] 10.1155/2021/5544742 PMC 바로가기 [Article Type] Research Article
Transgene Delivery to Human Induced Pluripotent Stem Cells Using NanoparticlesReview Published on 2021-04-062022-10-28 Journal: Pharmaceuticals [Category] COVID-19, [키워드] 2019 coronavirus disease Affect approach approach biodegradability Cell COVID-19 COVID-19 vaccines Culture cytotoxicity delivery demonstrated diagnostics directional distal Efficiency example facilitate functional generate Genetic Human human induced pluripotent stem cells human induced pluripotent stem cells-derived cardiomyocytes immune responses in vivo induced lack Magnetic nanoparticles Modification nanomedicine nanoparticle Nanoparticles Nanotechnology offer pluripotent stem cell powerful tool Precision provided regenerative robust SARS-CoV-2 SARS-CoV-2 vaccine somatic cell STEM these cell transfection transgene Vaccine [DOI] 10.3390/ph14040334 PMC 바로가기 [Article Type] Review
Potential APOBEC-mediated RNA editing of the genomes of SARS-CoV-2 and other coronaviruses and its impact on their longer term evolutionArticle Published on 2021-04-012022-10-28 Journal: Virology [Category] COVID-19, MERS, SARS, [키워드] Amino acid antiviral activity APOBEC base changes in coronavirus coronavirus genomes Coronaviruses COVID-19 pandemic Cytidine deaminase cytosine determine directional DNA viruses Evidence Evolution Genome genomic hallmark herpesvirus homoplasy Innate immunity knowledge mammalian cell member Occurrence other coronavirus other coronaviruses Potential reported RNA RNA virus SARS-CoV-2 SARS-CoV-2 genome sequence SARS-CoV-2 sequence sequence sustained variant Viral proteins Virus evolution [DOI] 10.1016/j.virol.2020.12.018 PMC 바로가기 [Article Type] Article