NETosis and Nucleosome Biomarkers in Septic Shock and Critical COVID-19 Patients: An Observational Study패혈성 쇼크 및 심각한 COVID-19 환자의 NETosis 및 뉴클레오솜 바이오마커: 관찰 연구Observational Study Published on 2022-07-272022-09-11 Journal: Biomolecules [Category] MERS, 바이오마커, 임상, [키워드] alternative Biomarker Biomarkers cell death conditions Control control subject COVID-19 Critical critical COVID-19 patient critical COVID-19 patients Defense discrimination disease severity evaluate extracellular trap histone ICU Infection Intact intensive care intensive care unit marker matched control mechanism microorganisms MPO myeloperoxidase NET NETosis NETs NETs’ formation neutrophil neutrophil activation neutrophil count Neutrophil elastase Neutrophil extracellular traps Neutrophils normalization Nucleosome nucleosomes P -value p -values patient cohort patients phagocytosis recruited Result SARS-CoV-2 septic Septic shock Septic shock. Significant significant differences Spread subject were measured [DOI] 10.3390/biom12081038 PMC 바로가기 [Article Type] Observational Study
Circulating suPAR associates with severity and in-hospital progression of COVID-19순환하는 suPAR은 COVID-19의 중증도 및 병원 내 진행과 관련이 있습니다.Observational Study Published on 2022-07-012022-09-11 Journal: European Journal of Clinical Investigation [Category] MERS, 바이오마커, 임상, [키워드] 95% CI Accuracy Admission Adult patients age albumin assays association AUC best characterized clinical correlated COVID-19 COVID-19 disease CRP discrimination Disease progression disease severity doubling EGFR ELISA females ferritin FIVE Hospital admission hyperinflammation IMPROVE In-hospital interleukin interleukin-6 International Lactate lactate dehydrogenase LDH Linear model male marker median age observational study outcome parameter patients patients hospitalized plasma suPAR predict primary outcome measure procalcitonin progression risk stratification scale serum albumin serum lactate severity severity of COVID-19 significantly significantly lower suPAR suPAR. survival survivor Treatment WHO WHO Clinical Progression Scale WHO-CPS [DOI] 10.1111/eci.13794 PMC 바로가기 [Article Type] Observational Study
Biomarkers Predictive for In-Hospital Mortality in Patients with Diabetes Mellitus and Prediabetes Hospitalized for COVID-19 in Austria: An Analysis of COVID-19 in Diabetes Registry오스트리아에서 COVID-19로 입원한 당뇨병 및 전당뇨병 환자의 병원 내 사망률을 예측하는 바이오마커: 당뇨병 등록부의 COVID-19 분석Multicenter Study Published on 2022-06-132022-09-11 Journal: Viruses [Category] MERS, 바이오마커, [키워드] age analyses Analysis association Biomarker Biomarkers calibration Clinical parameters Coagulation Comorbidities COVID-19 COVID-19 patients CRP demographic characteristics diabetes Diabetes Mellitus diabetes mellitus. discrimination disease severity hospital Hospital mortality Hospitalized IL-6 in-hospital mortality Inflammatory laboratory measurement laboratory measurements LDH Logistic regression Logistic regression analysis medication men multicenter cohort study Multiple logistic regression analysis NT-proBNP parameters Patient patients died patients with diabete PCT Prediabete prediabetes Predictive predictor variable Predictor variables Primary outcome registry SARS-CoV-2 significantly troponin troponin T Type 1 diabetes mellitus type 2 diabete Type 2 diabetes mellitus with COVID-19 [DOI] 10.3390/v14061285 PMC 바로가기 [Article Type] Multicenter Study
The unvirtuous cycle of discrimination affecting people with hepatitis B: a multi-country qualitative assessment of key-informant perspectivesPractice Guideline Published on 2022-05-312023-06-11 Journal: International journal for equity in health [Category] B형 간염, [키워드] discrimination health outcomes Hepatitis B virus Human rights Liver cancer marginalization Stigma. [DOI] 10.1186/s12939-022-01677-6 PMC 바로가기 [Article Type] Practice Guideline
Development and psychometric validation of new questionnaires assessing experienced discrimination and internalised stigma among people with Covid-19Article Published on 2022-05-262023-07-09 Journal: Epidemiology and Psychiatric Sciences [Category] COVID19(2023년), [키워드] COVID-19 discrimination internalised stigma psychometric validation. [DOI] 10.1017/S204579602200021X PMC 바로가기
Peak value of serum KL-6 may be useful for predicting poor prognosis of severe COVID-19 patients혈청 KL-6의 피크 값은 심각한 COVID-19 환자의 나쁜 예후를 예측하는 데 유용할 수 있습니다Observational Study Published on 2022-05-192022-09-11 Journal: European Journal of Medical Research [Category] MERS, 바이오마커, 임상, [키워드] 95% CI Accuracy adjusted odds ratio Admission age alveolar analysis Analysis analyzed Area AUC baseline characteristics best Biomarker Biomarkers Comorbidities Concentration COVID-19 COVID-19 patient COVID-19 patients criteria cut-off value defined determine discrimination early phase epithelial evaluate examination help high risk high-flow oxygen therapy higher risk Hospitalization hospitalized patient identify inclusion criteria indicated initial Injury Invasive mechanical ventilation KL-6 LDH Logistic regression analyses minimum multivariate logistic regression non-survivor observational study once a week oxygen Oxygen therapy Patient patients peak performed Pneumonitis poor prognosis predict Prognosis Prognosis. Prognostic value progression reflect reported required Respiratory failure retrospective sensitivity serum severe COVID-19 patient Sex single-center supplemental oxygen survivor Treatment U/mL [DOI] 10.1186/s40001-022-00690-3 PMC 바로가기 [Article Type] Observational Study
Psychosocial status of older adults aged 65 years and over during lockdown in Turkey and their perspectives on the outbreakArticle Published on 2022-05-012023-07-06 Journal: Health & social care in the community [Category] COVID19(2023년), [키워드] Awareness COVID-19 discrimination Equality loneliness mental health Older adults pandemic Psychosocial health Stigma yearn. [DOI] 10.1111/hsc.13542 PMC 바로가기
Comparison of chest CT severity scoring systems for COVID-19COVID-19에 대한 흉부 CT 중증도 점수 시스템 비교Article Published on 2022-05-012022-09-11 Journal: European Radiology [Category] COVID19(2023년), SARS, 치료기술, [키워드] abnormality Accuracy asked AUC calculated Chest CT Clinical severity Computed tomography Computed tomography, X-ray coronavirus COVID-19 CT chest cutoff value demonstrated diagnostic Diagnostic accuracy discrimination female FIVE highest Interpretation lung lung involvement male observation Patient PCR-confirmed PCR-confirmed COVID-19 pulmonary involvement Quantitative reported Reporting Retrospective study ROC Curve ROC curves SARS-CoV-2. scoring system Severe case severe cases severity significantly specificity statistically significant time tomography TSS X-ray [DOI] 10.1007/s00330-021-08432-5 PMC 바로가기 [Article Type] Article
The early use of sepsis scores to predict respiratory failure and mortality in non-ICU patients with COVID-19Case Reports Published on 2022-05-012022-10-05 Journal: Revista clínica española [Category] 임상, [키워드] adults hospitalized assessment coronavirus COVID-19 COVID-19 patients cutoff point death defined died discrimination Early warning scores English failure Fallo respiratorio Hospitalized ICU intensive care unit mechanical ventilation Mortality non-ICU patient occurred PaO Patient patients with COVID-19 predict qSOFA respiratory Respiratory failure Retrospective study SARS-CoV-2 score Sepsis Sepsis-Related Organ Failure Assessment. SOFA Spanish with COVID-19 [DOI] 10.1016/j.rceng.2020.10.004 PMC 바로가기 [Article Type] Case Reports
Performance of Immunoglobulin G Serology on Finger Prick Capillary Dried Blood Spot Samples to Detect a SARS-CoV-2 Antibody ResponseSARS-CoV-2 항체 반응을 검출하기 위한 핑거 프릭 모세관 건조 혈액 반점 샘플에 대한 면역글로불린 G 혈청학의 성능Article Published on 2022-04-272022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] 95% CI 95% confidence interval Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis anti-IgG antibody Blood bootstrap calculate Canada capillary children collected comparable conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cross-sectional cross-sectional study Data analysis DBS sample DBS samples detect diagnostic Diagnostic accuracy discrimination distributions Dried blood spots Epidemiology evaluate finger Finger prick IgG Immunoglobulin G Infection involved Logistic regression logistic regression model modeling multiplex natural infection operator participant performance Positive predictive value Predictive Predictive value public health Quantitative recipients respiratory response ROC ROC analysis Sample SARS-CoV-2 SARS-COV-2 infection sensitivity Seroconversion serological survey Seropositivity serum serum sample serum samples severe acute respiratory syndrome Coronavirus specificity spot subset tested threshold vaccination Vaccine vaccine dose vaccine evaluation. venipuncture were used [DOI] 10.1128/spectrum.01405-21 PMC 바로가기 [Article Type] Article