SARS-CoV-2 Genomic Characteristics and Clinical Impact of SARS-CoV-2 Viral Diversity in Critically Ill COVID-19 Patients: A Prospective Multicenter Cohort Study중증 COVID-19 환자에서 SARS-CoV-2 게놈 특성 및 SARS-CoV-2 바이러스 다양성의 임상 영향: 전향적 다기관 코호트 연구Observational Study Published on 2022-07-132022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 임상, [키워드] Acute respiratory failure association clinical clinical outcomes COPD COVID-19 COVIDSeq Diversity Endpoint genetic diversity groups had more higher risk hospital ICU admission ICUs Ill Illumina Impact intensive care intensive care unit Mortality multicenter Next-generation sequencing not differ Observational cohort study Older other variant other variants Paris Patient Prospective Respiratory failure SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants sequenced severe COVID-19 significantly SOFA score SOFA scores specific mutations Spread suggested the patient variant Variant of concern. variants were infected [DOI] 10.3390/v14071529 PMC 바로가기 [Article Type] Observational Study
Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2Omicron BA.1 및 BA.2에 효과적인 강력한 인간 SARS-CoV-2 중화 IgA 및 IgG 항체Article Published on 2022-07-042022-09-11 Journal: The Journal of Experimental Medicine [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] animal models antibody Antibody Response Antibody responses Antiviral B-cell boost breadth candidate Cell cellular contribute convalescent COVID-19 demonstrated Diversity effective effector elicited functions Humoral immunity IgA IgA antibodies IgA antibody IgG antibodies IgG antibody immune protection memory B memory B cell memory B-cell monoclonal antibody mucosal tissue mucosal tissues Neutralizing omicron potent prevented provided Receptor-binding domain S2 subunit SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike SARS-CoV-2 spike protein SARS-CoV-2 variant serological severe COVID-19 Spike protein the receptor-binding domain the SARS-CoV-2 therapeutic efficacy Treatment Wuhan [DOI] 10.1084/jem.20220638 PMC 바로가기 [Article Type] Article
Super Dominant Pathobiontic Bacteria in the Nasopharyngeal Microbiota Cause Secondary Bacterial Infection in COVID-19 Patients비인두 미생물총의 슈퍼 우세한 병원성 박테리아는 COVID-19 환자에서 2차 박테리아 감염을 유발합니다Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] Coronavirus, COVID19(2023년), SARS, 치료기술, [키워드] 16S rRNA 16S rRNA gene abundance accounted Acinetobacter aggravate analyzed Bacterial Bacterial infection bacterial pneumonia bacterial specy cause collected Community composed coronavirus disease Coronavirus disease 2019 Corynebacterium Coverage COVID-19 COVID-19 infection COVID-19 patient defined difference disease severity Diversity dominant fatality genus High-throughput sequencing Infection Influenza invasive Lower respiratory tract lower respiratory tract samples microbiota Mild mild COVID-19 patients mild infection mild infections nasopharyngeal nasopharyngeal microbiota nasopharynx pathobiontic bacteria pathogen Patient patients patients with SARS-CoV-2 Pneumonia previous study respiratory infectious disease respiratory tracts responsible rRNA Sample SARS-COV-2 infection secondary secondary bacterial infection secondary bacterial infection. secondary bacterial pneumonia Seven severe COVID-19 Severe COVID-19 Infection severe COVID-19 patients severe group severe pneumonia significantly significantly higher Staphylococcus upper upper and lower respiratory tracts upper respiratory tract variety was used [DOI] 10.1128/spectrum.01956-21 PMC 바로가기 [Article Type] Article
Epidemiological and virological surveillance of influenza viruses in China during 2020-20212020-2021년 동안 중국에서 인플루엔자 바이러스의 역학 및 바이러스 감시Article Published on 2022-06-292022-09-11 Journal: Infectious Diseases of Poverty [Category] COVID19(2023년), SARS, 치료제, [키워드] accompanied acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition analyses Analysis analyzed antigenic antigenic diversity Antiviral antiviral medication Antiviral medications B/Victoria lineage viruses caused Characteristics characterized China Chinese circulating collected component components conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic declined Diversity Epidemic epidemiological Epidemiology flu Genetic genetic diversity Hemisphere hospital Influenza influenza like illness Influenza virus influenza virus influenza viruses inhibitors isolate Laboratory Lineage mainland molecular Mutation network neuraminidase inhibitor neuraminidase inhibitors Next-generation sequencing outbreak pandemic phenotypic Phylogenetic analysis preventive measure preventive measures reduced Region remained representing respiratory respiratory specimens respond SARS-CoV-2 Seasonal influenza sensitivity Sequencing severe acute respiratory syndrome Coronavirus specimen study period Surveillance susceptibility tested the vaccine unique Virological Virological. virus virus viruses was performed was used Winter [DOI] 10.1186/s40249-022-01002-x PMC 바로가기 [Article Type] Article
Detection of SARS-CoV-2 intra-host recombination during superinfection with Alpha and Epsilon variants in New York City뉴욕시에서 알파 및 엡실론 변이체로 중복 감염 중 SARS-CoV-2 숙주 내 재조합 검출Article Published on 2022-06-252022-09-11 Journal: Nature Communications [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 치료기술, 치료법, 치료제, [키워드] allele Alpha Alpha variant B.1.1.7 B.1.429 classic coding regions Coronavirus replication detection Diversity Epsilon feasible full genome sequencing functions generate genetic diversity Genome genome sequence genomes Haplotype Host identify independent individual infect New York City nucleocapsid Occurrence ORF pathogen Pathogens Recombination reveal S gene SARS-CoV-2 superinfection Support variant virus [DOI] 10.1038/s41467-022-31247-x PMC 바로가기 [Article Type] Article
Transmission networks of SARS-CoV-2 in Coastal Kenya during the first two waves: A retrospective genomic study처음 두 파동 동안 케냐 해안에서 SARS-CoV-2의 전송 네트워크: 후향적 게놈 연구Article Published on 2022-06-142022-09-11 Journal: eLife [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Africa AID analysed Analysis B.1.1 city collected Commonwealth coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 development dispersal Diversity Epidemiology expressed followed by force Foreign genomic Genomics global health Government Health Infection infections Infectious disease International Intervention Kenya Lamu Lineage lineage B.1 lineages Local local public health Microbiology Mombasa MOST NIHR occurred office over pandemic phylogeographic analysis positive sample reduce Research resulting retrospective river SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 virus sequenced severe acute respiratory syndrome Coronavirus Spread study period sub-Saharan Africa Support Taita Transmission transmission pattern Travel UK Government virus viruses viruses. Wave [DOI] 10.7554/eLife.71703 PMC 바로가기 [Article Type] Article
Genome-Wide Reassortment Analysis of Influenza A H7N9 Viruses Circulating in China during 2013-2019Article Published on 2022-06-092023-06-22 Journal: Viruses [Category] 조류인플루엔자, [키워드] Avian influenza virus Diversity H7N9 highly pathogenic Reassortment Tanglegram. [DOI] 10.3390/v14061256 PMC 바로가기
Genomic Diversity of SARS-CoV-2 Omicron Variant in South American Countries남미 국가에서 SARS-CoV-2 오미크론 변이체의 게놈 다양성Article Published on 2022-06-072022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 변종, 유전자 메커니즘, 진단, [키워드] acquisition addition Analysis antibody B.1.1.529 Characteristics circulating variants continent contributed dispersal Diversity dominant epidemiological favor Genome genomic genomic information Genomic surveillance identify Lineage lineages mechanism Mutation mutations nucleotide nucleotide diversity omicron omicron sublineages Phylogenetic relationship phylogenomic analysis. provided public health SARS-CoV-2 South South America Surveillance Transmission variant [DOI] 10.3390/v14061234 PMC 바로가기 [Article Type] Article
Coronavirus and Paramyxovirus Shedding by Bats in a Cave and Buildings in Ethiopia에티오피아의 동굴과 건물에서 박쥐에 의한 코로나바이러스 및 파라믹소바이러스 발산Article Published on 2022-06-012022-09-11 Journal: EcoHealth [Category] COVID19(2023년), SARS, 치료기술, [키워드] alphacoronavirus bat bats Biogeography building cave Combination Consensus coronavirus coronavirus CoV dependent on Diversity Ethiopia expand Factor filoviruses FIVE geographic locations Host immunology include Infection knowledge life history novel coronavirus pandemic paramyxovirus PCR assay positive rectal swab Rectal swabs risk reduction SARS-CoV SARS-CoV-2 shedding stressors Surveillance tested traits Transmission viral infection viral shedding Viral shedding. virus wet season wildlife zoonotic zoonotic disease [DOI] 10.1007/s10393-022-01590-y PMC 바로가기 [Article Type] Article
Present and future distribution of bat hosts of sarbecoviruses: implications for conservation and public healthArticle Published on 2022-05-252023-07-09 Journal: Proceedings of the Royal Society B: Biological Sci [Category] COVID19(2023년), [키워드] Climate change Diversity ecological niche models Forecasting. SARS-like coronavirus [DOI] 10.1098/rspb.2022.0397 PMC 바로가기