How the Innate Immune System of the Blood Contributes to Systemic Pathology in COVID-19-Induced ARDS and Provides Potential Targets for Treatment
혈액의 타고난 면역 체계가 COVID-19 유발 ARDS의 전신 병리에 기여하고 치료를 위한 잠재적인 표적을 제공하는 방법
Review
[키워드] Activation
Acute kidney injury
acute respiratory distress
acute respiratory distress syndrome
AMY-101
Angiogenesis
apoptotic cells
ARDS
Biomarker
bradykinin
candidate drug
candidate drugs
cascade
cascade system
characterized
chemokines
Coagulation
Coagulation system
complement
Complement inhibitor
complement inhibitors
Compound
COVID-19
Crosstalk
cytokine
Cytokines
damaged
demonstrated
dysregulation
ecallantide
eculizumab
Evidence
favor
ground glass opacities
heparin
High dose
high risk
Icatibant
IL-6
IL-6 levels
in some
incidence
include
Influenza
influenza-like symptom
Influenza-like symptoms
inhibitor
initiated
Innate
innate immune system
intensive care treatment
Kallikrein
lanadelumab
lead
leukocytes
life-threatening
LMWH
Lung injury
mechanical ventilation
mechanism
moderate
MOST
oxygen
oxygen saturation
pandemic
pathophysiology
Patient
patients
Phase I
plasma
plasma proteins
Platelets
Potential
predict
Prevent
Prognostic value
pulmonary damage
pulmonary inflammation
receptor
reduced
Regulation
respiratory distress
Respiratory distress syndrome
SARS-CoV-2
SARS-CoV-2 infected patient
severity
Support
survival
syndrome
System
systemic
target
the disease
therapeutic option
therapeutic options
Thromboembolism
thrombosis
thrombotic
Thrombotic complications
translated
Treatment
treatment of COVID-19
Trial
Usage
Vascular
ventilator
virus
[DOI] 10.3389/fimmu.2022.840137 PMC 바로가기 [Article Type] Review
[DOI] 10.3389/fimmu.2022.840137 PMC 바로가기 [Article Type] Review