eosinophil – Page 2 – Communicable Diseases Research

Vaccine-associated enhanced respiratory pathology in COVID-19 hamsters after T H 2-biased immunization

T H 2 편향 예방 접종 후 COVID-19 햄스터의 백신 관련 향상된 호흡기 병리학

Article

Published on 2022-08-162022-09-11
Journal: Cell Reports [Category] 유전자 메커니즘, 진단,

A retrospective study of age-defined hematologic inflammatory markers related to pediatric COVID-19 diagnosis

소아 코로나19 진단과 관련된 연령 정의 혈액 염증 표지자에 대한 후향적 연구

Article

Published on 2022-08-012022-09-11
Journal: International journal of laboratory hematology [Category] 바이오마커,

Eosinophilic esophagitis auxiliary diagnosis based on a peptide ligand to eosinophil cationic protein in esophageal mucus of pediatric patients

Research

Published on 2022-07-182022-10-05
Journal: Scientific Reports [Category] 바이오마커,

SARS-CoV-2-Specific Adaptive Immunity in COVID-19 Survivors With Asthma

천식이 있는 COVID-19 생존자의 SARS-CoV-2-특이적 적응 면역

Article

Published on 2022-07-182022-09-12
Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단,

[키워드] adaptive allergy analyzed Asthma asthmatic asthmatic patient benefit Blood Cell Clinical characteristics convalescent correlated COVID-19 COVID-19 patient discharge eosinophil Follow-up healthy control Humoral immunity immune immune memory Immunity individual Lymphocyte subsets memory B cell memory T cells NAb NAbs Neutralization assay Neutralizing antibodies no statistical difference Non-COVID-19 not significantly different Patient percentages positively correlated SARS-CoV-2 pseudotyped virus SARS-CoV-2 specific antibodies SARS-CoV-2-specific neutralizing antibody skewed subjects survivor T cell T cell response T cell responses Th1 Th17 cell Treg Treg cell virus infection virus-specific T cell
[DOI] 10.3389/fimmu.2022.947724 PMC 바로가기 [Article Type] Article

Routine laboratory parameters, including complete blood count, predict COVID-19 in-hospital mortality in geriatric patients

전체 혈구 수를 포함한 일상적인 실험실 매개변수는 노인 환자의 COVID-19 병원 내 사망률을 예측합니다

Article

Published on 2022-06-012022-09-12
Journal: Mechanisms of ageing and development [Category] MERS, 바이오마커, 진단,

[키워드] adjusted age Ancona baseline Blood C-reactive protein CCI clinical Comorbidity complete blood count confounders COVID-19 Cox regression criteria death Deceased enrolled eosinophil evaluate frailty Gender highest hospital Hospitalized IL-6 In-hospital in-hospital mortality increased risk independent Italy laboratory biomarker Laboratory parameters Lymphocyte count lymphopenia Mortality neutrophil Neutrophil-to-lymphocyte ratio NLR NT-proBNP older patients parameters Patient patients predict Predictive predictor procalcitonin reduce routine scale selected significantly significantly increased Support survived
[DOI] 10.1016/j.mad.2022.111674 PMC 바로가기 [Article Type] Article

Early Th2 inflammation in the upper respiratory mucosa as a predictor of severe COVID-19 and modulation by early treatment with inhaled corticosteroids: a mechanistic analysis

중증 COVID-19의 예측인자로서 상부 호흡기 점막의 초기 Th2 염증 및 흡입 코르티코스테로이드 조기 치료에 의한 조절: 기계론적 분석

Clinical Trial

Published on 2022-06-012022-09-11
Journal: The Lancet. Respiratory Medicine [Category] COVID19(2023년), SARS, 바이오마커, 신약개발, 임상, 치료법, 치료제,

[키워드] 1:1 adaptive airway Analysis Anti-viral antipyretics assigned AstraZeneca Biomarker Blood blood sample Blood samples Budesonide CCL17 chemokine clinical benefit clinical symptom clinical trial clinically Cohort collected Concentration Corticosteroid Course COVID-19 COVID-19 disease COVID-19 disease course Data collection decrease deteriorate dose early treatment Efficacy elevated enzyme eosinophil epithelial epithelial lining Evolution experimental analysis healthy controls healthy individuals IL-33 immunoassay individual Inflammation Inflammatory Inflammatory mediators Inflammatory response Inhaled inhaled budesonide inhaled corticosteroid initial interferon interferon response interleukin Intervention investigated Ligand marker mechanism Meso Scale Discovery modulated modulation mucosa mucosal nasal Nasal sample nasal samples Necrosis negative control nose Observational data open label outcomes over Oxford parallel group participant Patient patients with SARS-CoV-2 Phase 2 Primary outcome Proteins randomisation randomised Randomly receive recruited reducing Registered respiratory tract SARS-COV-2 infection severe COVID-19 severe COVID-19 disease shown systemic inflammation T-cell Response Th2 the SARS-CoV-2 Treatment Trial tumour necrosis factor tumour necrosis factor-α twice a day University of Oxford upper respiratory usual care usual care group was collected were assessed were used Whole blood with COVID-19
[DOI] 10.1016/S2213-2600(22)00002-9 PMC 바로가기 [Article Type] Clinical Trial

Co-Expression and Localization of Angiotensin-Converting Enzyme-2 (ACE2) and the Transmembrane Serine Protease 2 (TMPRSS2) in Paranasal Ciliated Epithelium of Patients with Chronic Rhinosinusitis

Article

Published on 2022-05-012023-07-07
Journal: American Journal of Rhinology & Allergy [Category] COVID19(2023년),

[키워드] ACE2 CRS eosinophil epithelial ciliated cell IFN-γ IL-13 SARS-CoV-2 TMPRSS2 TNF-α type 1 immune response.
[DOI] 10.1177/19458924211059639

First Identified Case of Fatal Fulminant Necrotizing Eosinophilic Myocarditis Following the Initial Dose of the Pfizer-BioNTech mRNA COVID-19 Vaccine (BNT162b2, Comirnaty): an Extremely Rare Idiosyncratic Hypersensitivity Reaction

Pfizer-BioNTech mRNA COVID-19 백신(BNT162b2, Comirnaty)의 초기 투여 후 치명적인 전격성 괴사성 호산구성 심근염의 첫 번째 확인된 사례: 극히 드문 특발성 과민 반응

Case Reports

Published on 2022-04-012022-09-12
Journal: Journal of Clinical Immunology [Category] 진단,

COVID-19 IgG/IgM patterns, early IL-6 elevation and long-term radiological sequelae in 75 patients hospitalized due to interstitial pneumonia followed up from 3 to 12 months

간질성 폐렴으로 입원한 75명의 환자에서 코로나19 IgG/IgM 패턴, 초기 IL-6 상승 및 장기 방사선학적 후유증을 3개월에서 12개월 동안 추적 관찰했습니다.

Research Article

Published on 2022-02-222022-09-12
Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술,

[키워드] antibody association baseline baseline levels Clinical outcome clinical outcomes Coagulation Computed tomography Concentration COVID-19 COVID-19 disease COVID-19 pandemic death decrease detectable discharged dosage ELISA test eosinophil Eosinophil count Follow-up Generalized Generalized linear model GLM GPT highlighting hospital Hospital admission Hospitalization IgG IgG and IgM IgG antibodies IgG antibody IgG level IgG/IgM antibodies IgG/IgM antibody IgM IgM antibodies IL-6 increase in Infection Inflammatory marker inflammatory markers intensive care interstitial pneumonia Laboratory tests lung Model Negative PCR observé one patient parameter Patient patients patients hospitalized pattern PCR test persistence Platelet Platelets radiological radiological feature radiological features Result RNA serological Serum level statistically significant subject subsequent supported throat swab Trigger was performed was used
[DOI] 10.1371/journal.pone.0262911 PMC 바로가기 [Article Type] Research Article

Cutaneous and systemic hyperinflammation drives maculopapular drug exanthema in severely ill COVID-19 patients

피부 및 전신 고인 염증은 심하게 아픈 Covid-19 환자에서 황반 약물 엑스 산마를 유도합니다.

Article

Published on 2022-02-012022-08-31
Journal: Allergy [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 치료기술, 치료제,

[키워드] activated Activation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis analyzed CCL11 CD8 cellular chemokine chemokines Cluster Clustering coronavirus coronavirus disease coronavirus disease-2019 COVID-19 COVID-19 patient COVID-19 patients Cutaneous cytokine Cytokine storm Cytometry demonstrated Diagnosis drug rash drug-induced maculopapular exanthema. eosinophil eosinophilia Exanthema Features healthy controls hypersensitivity hypersensitivity reaction hypersensitivity reactions IFN-γ IL-4 IL-5 IL-6 inflammatory mediator Inflammatory mediators Macrophage MCP-3 MDR mediators nasopharyngeal Patient PCR performed positive promote proteomic rashe respiratory RNA sequencing robust SARS-CoV-2 serum severe acute respiratory syndrome Coronavirus severe COVID-19 patients skin biopsies skin biopsy systemic cytokine systemic hyperinflammation systemic symptom systemic symptoms T cell T cells TNF Transcriptome turn upregulation
[DOI] 10.1111/all.14983 PMC 바로가기 [Article Type] Article