Essential oil-mediated biocompatible magnesium nanoparticles with enhanced antibacterial, antifungal, and photocatalytic efficacies Research Published on 2022-07-062022-10-05 Journal: Scientific Reports [Category] 치료제, [키워드] acute respiratory syndrome antimicrobial agent Antimicrobials approach attribute coronavirus disease COVID-19 Cymbopogon Degradation Diseases Efficacy Escherichia coli Essential exhibited functional Fusarium highlight imperative investigated microbial infections multifunctional outcome physicochemical reducing reduction Staphylococcus aureus Symptomatic treatment Treatment [DOI] 10.1038/s41598-022-14984-3 [Article Type] Research
Effective Natural Killer Cell Degranulation Is an Essential Key in COVID-19 EvolutionObservational Study Published on 2022-06-132022-10-05 Journal: International Journal of Molecular Sciences [Category] 임상, [키워드] Analysis analyzed association Benign Cell clearance complex conducted Control COVID-19 COVID-19 patient cytotoxic activity degranulation degranulation activity early stage Essential Evolution expression form forms granzymes healthy control hospital identify Immune cell immunological profile independent risk factor Infection Innate innate immune cell Innate immunity natural natural killer natural killer. NK cell NKG2D NKT cell non-severe patient outcome Patient prospective observational study protective factor severe patients severity subjects subpopulation the disease the healthy [DOI] 10.3390/ijms23126577 PMC 바로가기 [Article Type] Observational Study
At Least Three Doses of Leading Vaccines Essential for Neutralisation of SARS-CoV-2 Omicron VariantSARS-CoV-2 오미크론 변이체 중화에 필수적인 주요 백신 최소 3회 투여Article Published on 2022-05-172022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] AlphaFold AstraZeneca biomolecular modelling coronavirus disease Coronavirus disease-19 COVID-19 Delta different time point different time points Donor donors dose equity Essential followed by Gender generate leading limit of detection Moderna neutralisation Neutralising Antibodies neutralising antibody neutralising antibody titres neutralizing antibody titre Older omicron Omicron variants Pfizer plasma samples reduction in SARS-CoV-2 second dose significantly Spike protein timepoints titre titres Vaccine Vaccines variants variants of concern virus neutralization assay virus neutralization assays were assessed [DOI] 10.3389/fimmu.2022.883612 PMC 바로가기 [Article Type] Article
Systematic on-site testing for SARS-CoV-2 infection among asymptomatic essential workers in Montréal, Canada: a prospective observational and cost-assessment studyObservational Study Published on 2022-05-102022-10-04 Journal: CMAJ open [Category] Coronavirus, COVID19(2023년), SARS, 임상, [키워드] 95% CI 95% confidence interval adjusted adjusted odds ratio Analysis analyzed appear Asymptomatic auto Canada Care composed effort Essential essential worker evaluated Factor female final visit increased risk initial interquartile range median median age multivariable logistic regression outbreak Outbreaks participant participated performed polymerase chain positive positive result positive test result Prevent Primary outcome professionals proportion provided recruited repeated reported reverse transcription RT-PCR Sample SARS-COV-2 infection SARS-CoV-2 test SARS-CoV-2 testing SARS-CoV-2 transmission secondary outcome telephone contact tested [DOI] 10.9778/cmajo.20210290 PMC 바로가기 [Article Type] Observational Study
Agathis robusta Bark Essential Oil Effectiveness against COVID-19: Chemical Composition, In Silico and In Vitro ApproachesArticle Published on 2022-02-282022-10-28 Journal: Plants [Category] COVID-19, [키워드] Analysis Antiviral antiviral activity approved binding affinity Chemical component components Compound contribute coronavirus 2 COVID-19 Cytopathic effect demonstrated docking drug effective Environment Enzymes Essential essential oil Gas Chromatography-Mass Spectrometry GC-MS Health inhibition assay investigated MPro MTT Oil protease RBD RdRP respiratory RNA-dependent RNA polymerase SARS-CoV2 selected spike receptor-binding domain suggested targets the RBD Treatment Vaccines [DOI] 10.3390/plants11050663 PMC 바로가기 [Article Type] Article
Towards an Accurate Estimation of COVID-19 Cases in Kazakhstan: Back-Casting and Capture–Recapture ApproachesArticle Published on 2022-02-082022-10-30 Journal: Medicina [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] approach back-casting approach capture–recapture method consequence coronavirus disease 19 COVID-19 death diagnostic effective effort Epidemic epidemiological Essential estimation Fatality rate implementation individual Infection Kazakhstan magnitude material Measures methodology mortality data novel coronavirus SARS-CoV-2 number of infected reducing SARS-CoV-2 SARS-CoV-2 infections Surveillance sustained vaccination [DOI] 10.3390/medicina58020253 PMC 바로가기 [Article Type] Article
Molecular Docking and Molecular Dynamics Simulations Discover Curcumin Analogue as a Plausible Dual Inhibitor for SARS-CoV-2Article Published on 2022-02-042022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, COVID19(2023년), SARS, [키워드] activities addition analogue anticancer Antiviral binding binding affinity binding pocket Cancer Compound compounds COVID-19 Curcumin DDX3 demonstrated deviation disease dual inhibitor Dynamics effective Essential global pandemic hydrogen bond interactions inhibitor inhibitory activity Interaction main protease MDs molecular Molecular dynamics simulation natural compound analogues radius of gyration residue retrieved RMSD SARS-CoV-2 SARS-CoV-2 main protease shown Simulation stability [DOI] 10.3390/ijms23031771 PMC 바로가기 [Article Type] Article
[Translated article] Hydroxychloroquine: An Essential Drug in Dermatology and Its Controversial Use in COVID-19Research article Published on 2022-02-012022-10-05 Journal: Actas Dermo-Sifiliográficas [Category] 치료제, [키워드] adverse effects Anti-inflammatory antimalarial antiviral properties breastfeeding women can be used caused children clinical COVID-19 Dermatology Diseases drug erythematous Essential granuloma Hydroxychloroquine immune system immunomodulatory Lichen planus lupus erythematosus Meta-analysis porphyria pregnant Prevent recent Regular safety profile sarcoidosis SARS-CoV-2 supply shortage Supply shortages suppress therapy treat [DOI] 10.1016/j.ad.2022.01.012 [Article Type] Research article
Essential Versus Nonessential: The Ethics of Conducting Non-COVID Research in a Population of Persons Living With Serious Illness During the COVID-19 PandemicRandomized Controlled Trial Published on 2022-02-012022-10-05 Journal: Journal of hospice and palliative nursing : JHPN : the official journal of [Category] COVID19(2023년), SARS, 임상, [키워드] activities activity Care conducted Conducting COVID-19 COVID-19 pandemic Effect Essential Ethics Guidance hospital illness Intervention involved Local Nurse Nurses Palliative care pandemic participant Patient Person Perspective Population Primary outcome protocol provide Randomized controlled trial Research secondary outcome tension usual care [DOI] 10.1097/NJH.0000000000000808 PMC 바로가기 [Article Type] Randomized Controlled Trial
Inhibition of Escherichia Virus MS2, Surrogate of SARS-CoV-2, via Essential Oils-Loaded Electrospun Fibrous Mats: Increasing the Multifunctionality of Antivirus Protection MasksArticle Published on 2022-01-272022-10-28 Journal: Pharmaceutics [Category] COVID-19, [키워드] affected antimicrobial Antiviral antiviral essential oils average Combination combinations Concentration COVID-19 demonstrated effective electrospun fibers Escherichia Escherichia coli Essential examined exhibiting Face masks fiber Gas Chromatography-Mass Spectrometry Increasing infiltration inhibit inhibition Log reduction Mask Masks Mat measure MS2 overcome penetration physisorption versus blending Polymer prevented processed protection reduce SARS-CoV-2 SARS-CoV-2 surrogate SARS-CoV-2 transmission Scent selected surrogate viability viral inhibitors viral particle virucidal virus was used [DOI] 10.3390/pharmaceutics14020303 PMC 바로가기 [Article Type] Article