Utilization of the Abbott SARS-CoV-2 IgG II Quant Assay To Identify High-Titer Anti-SARS-CoV-2 Neutralizing Plasma against Wild-Type and Variant SARS-CoV-2 VirusesArticle Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] 95% confidence interval Abbott Abbott SARS-CoV-2 IgG acute respiratory syndrome Analysis approach approach authorization BAU Beta binding antibody unit Canada CCP characterized Chicago Chicago IL clinical trial convalescent convalescent plasma coronavirus COVID-19 COVID-19 convalescent plasma Cutoff Delta disease course drug Emergency EUA evaluated Evidence experiment FDA food Gamma highest hospitalized patient Humoral immunity identify IgG immune IMPROVE Mann-Whitney U method comparisons Neutralization assay Neutralizing neutralizing antibody outcome Patient patient group plaque reduction neutralization plaque reduction neutralization. plasma PRNT quantitative determination required SARS-CoV-2 SARS-CoV-2 antibody selected significantly specimen tested the SARS-CoV-2 time-consuming treat United State utilization variant VLP VoC wild-type with COVID-19 [DOI] 10.1128/spectrum.02811-22 PMC 바로가기
Screening and evaluation of cytotoxicity and antiviral effects of secondary metabolites from water extracts of Bersama abyssinica against SARS-CoV-2 DeltaArticle Published on 2022-10-262022-11-15 Journal: BMC Complementary Medicine and Therapies [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] Acetate activities Analysis Anti-viral anti-viral agents antioxidant antiviral activity Antiviral effect Asthma bacterial respiratory infections Bersama abyssinica bioactive compounds bronchitis BSL-3 component Compound Concentration conducted coronavirus Coviba Dawa COVID-19 COVID-19 symptoms cytotoxicity Delta delta variant determine ether experiment fraction in vitro ingredient Isolation level 3 medication methanol Phenols polar procedure propionate Registered respiratory disorder SARS-CoV-2 Screening Secondary Metabolite Standard Tanzania temperature tested the SARS-CoV-2 Traditional Traditional medicine. treat VERO E6 cells viral pathogen virus was done was obtained water [DOI] 10.1186/s12906-022-03754-3 PMC 바로가기
A molecularly engineered, broad-spectrum anti-coronavirus lectin inhibits SARS-CoV-2 and MERS-CoV infection in vivoArticle Published on 2022-10-182022-11-15 Journal: Cell Reports Medicine [Category] COVID19(2023년), SARS, 변종, 진단, 치료제, [키워드] ACE2 acute respiratory syndrome Administered Antiviral antiviral activity association atomic Atomic force microscopy banana binding binding site cellular component concentrations conserved coronavirus coronavirus effective experiment glycan healthy high affinity high-mannose human cells identify in vivo inhibit intranasally intraperitoneally lack lectin MERS-CoV MERS-CoV infection Microscopy Middle East modeling omicron PROTECT recognize resistant mutants respiratory syndrome coronavirus SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike single-molecule force spectroscopy spike spike trimer target the SARS-CoV-2 Treatment Treatment. Viral protein virus entry [DOI] 10.1016/j.xcrm.2022.100774 PMC 바로가기
Longitudinal characterization of circulating neutrophils uncovers phenotypes associated with severity in hospitalized COVID-19 patientsArticle Published on 2022-10-182022-11-15 Journal: Cell Reports Medicine [Category] COVID19(2023년), SARS, 유전자 메커니즘, 진단, [키워드] acute respiratory syndrome antibody profiling blood sample cell death circulating neutrophil contributing to Control coronavirus COVID-19 degranulation disease disease severity driver dysregulated elevated experiment functions G-MDSC gene expression signature Granulocytic healthy donor hospitalized COVID-19 hospitalized COVID-19 patient Humoral response identify IgA IgA antibody IgG antibody Immunoglobulin induce longitudinal Mortality NETosis neutrophil Neutrophils Patient phagocytosis phenotype plasma plasma proteomics response RNA sequencing SARS-CoV-2 severe coronavirus disease severe COVID-19 severe disease Severe patient severity Subtypes survived transcriptomics transcriptomics. [DOI] 10.1016/j.xcrm.2022.100779 PMC 바로가기
Potential Therapeutic Approach of Melatonin against Omicron and Some Other Variants of SARS-CoV-2Article Published on 2022-10-162022-11-15 Journal: Molecules [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] Anti-inflammatory antioxidant antiviral drug applied caused clinical trial Combination contagious coronavirus COVID-19 COVID-19 disease COVID-19 severity disease Diseases drug effective Efficacy experiment Immunity immunomodulatory effects Infection melatonin mutations omicron Omicron variant (B.529) Other outbreak Outbreaks over oxidative oxidative stress Potential Prevent reduce reducing safety profile SARS-CoV-2 severe symptom severity shown significant effect the disease therapeutic Therapeutic approach therapeutic approach. therapeutic drug therapy treat Treatment unique Vaccine variant [DOI] 10.3390/molecules27206934 PMC 바로가기
Virological characteristics of the SARS-CoV-2 Omicron BA.2 subvariants, including BA.4 and BA.5Article Published on 2022-10-132022-11-15 Journal: Cell [Category] COVID19(2023년), SARS, 진단, [키워드] ACE2 binding alveolar epithelial cell BA.2 BA.2.12.1 BA.4 BA.5 bind Characteristics COVID-19 Culture effective experiment greater hamster Health human ACE2 immune immune evasion immune resistance Immunity Infection less omicron pathogenic pathogenicity provided replicate Reproduction number risk SARS-CoV-2 spike receptor-binding domain Spread statistical analysis Substitution suggested the SARS-CoV-2 Transmissibility Transmissibility. [DOI] 10.1016/j.cell.2022.09.018 PMC 바로가기
In vitro inhibition of SARS-CoV-2 Infection by dry algae powdersArticle Published on 2022-10-122022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 치료제, [키워드] antiviral activity antiviral property Arthrospira candidate Chlorella COVID-19 CPE Culture DMEM DMSO experiment fucoidan highest in viral in vitro incubated Infection inhibited investigated Post-infection purified reduced Safe Sargassum SARS-CoV-2 SARS-COV-2 infection significantly solvent supernatant TCID therapeutic Treatment Vero Cell viral inoculum Viral RNA was increased was used [DOI] 10.1038/s41598-022-22148-6 PMC 바로가기
Development of a low-cost multi-channel nucleic acid detection PCR instrument and clinical detection application of COVID-19Article Published on 2022-10-092022-11-15 Journal: Analytica chimica acta [Category] COVID19(2023년), SARS, 치료기술, [키워드] amplification COVID-19 COVID-19 outbreak development disadvantage Double channel experiment hospital Low-cost novel Novel coronavirus Nucleic acid detection optical PCR Quantitative quantitative PCR quantitative PCR instrument Real-time fluorescence quantitative PCR. variety were used [DOI] 10.1016/j.aca.2022.340338 PMC 바로가기
Respondent Fatigue Reduces Dietary Diversity Scores Reported from Mobile Phone Surveys in Ethiopia during the COVID-19 PandemicArticle Published on 2022-10-062022-11-16 Journal: The Journal of Nutrition [Category] 비임상, [키워드] assigned collected comparison country COVID-19 COVID-19 pandemic decrease dietary dietary diversity Diversity Effect Ethiopia Ethiopian experiment fatigue FIVE fixed food group groups highlighting Impact information measure Metrics Mobile Older outcome phone survey Primary outcome question Randomized Randomly reported respondent response response fatigue. score secondary survey trade-off Volume were assessed women [DOI] 10.1093/jn/nxac153 PMC 바로가기
Monkeypox Virus Detection Using Pre-trained Deep Learning-based ApproachesArticle Published on 2022-10-062022-11-15 Journal: Journal of medical systems [Category] Fulltext, 원숭이두창, 치료기술, [키워드] addition approach average classification community transmission COVID-19 COVID-19 virus dataset deep deep learning detect detection early stage experiment fine-tune Health help identify IMPROVE Infection majority Monkeypox pandemic Practitioner SARS-CoV2. virus virus detection widespread [DOI] 10.1007/s10916-022-01868-2 PMC 바로가기