Ginkgo biloba extracts improve choroidal circulation leading to suppression of myopia in micearticle Published on 2023-03-072024-09-05 Journal: Burma Med J [Category] update2024, [키워드] Experimental models of disease Preclinical research Refractive errors [DOI] 10.1038/s41598-023-30908-1 PMC 바로가기 [Article Type] article
Estimating immunity with mathematical models for SARS-CoV-2 after COVID-19 vaccinationarticle Published on 2023-03-062024-09-05 Journal: NPJ Vaccines [Category] update2024, [키워드] Experimental models of disease Outcomes research [DOI] 10.1038/s41541-023-00626-w PMC 바로가기 [Article Type] article
SARS-CoV-2 infection augments species- and age-specific predispositions in cotton ratsarticle Published on 2023-01-142024-09-05 Journal: Burma Med J [Category] update2024, [키워드] Experimental models of disease viral infection [DOI] 10.1038/s41598-022-27328-y PMC 바로가기 [Article Type] article
Characterisation and natural progression of SARS-CoV-2 infection in ferretsArticle Published on 2022-04-052023-07-02 Journal: Scientific Reports [Category] COVID19(2023년), SARS, [키워드] Experimental models of disease SARS-CoV-2 viral infection [DOI] 10.1038/s41598-022-08431-6 PMC 바로가기 [Article Type] Article
Positron emission tomography and magnetic resonance imaging of the brain in experimental human malaria, a prospective cohort study실험적 인간 말라리아에서의 뇌의 양전자 방출 단층촬영 및 자기 공명 영상, 전향적 코호트 연구Article Published on 2022-04-052024-08-01 Journal: Burma Med J [Category] 말라리아, [키워드] Experimental models of disease Parasite biology Parasite host response [DOI] 10.1038/s41598-022-09748-y PMC 바로가기
Three doses of prototypic SARS-CoV-2 inactivated vaccine induce cross-protection against its variants of concern프로토타입 SARS-CoV-2 비활성화 백신의 3회 용량은 우려되는 변이체에 대한 교차 보호를 유도합니다Article Published on 2022-02-252022-09-10 Journal: Signal Transduction and Targeted Therapy [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] Alpha anal swabs Beta COVID-19 cross-protection Delta dose evaluate Experimental models of disease extension followed by geometric mean geometric mean titer GMT in vivo Inactivated vaccine induce Infectious diseases lung nasal Neutralizing antibodies neutralizing antibody omicron Omicron variants pandemic pathological change pathological changes Prevention and control produced reduced Rhesus monkey Rhesus monkeys SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 variant tissues Vaccine variant variants variants of concern Viral Viral load viral loads VoC VOCs [DOI] 10.1038/s41392-022-00920-4 PMC 바로가기 [Article Type] Article
Enhanced fitness of SARS-CoV-2 variant of concern Alpha but not Beta베타가 아닌 알파의 SARS-CoV-2 변종에 대한 향상된 적합성Comparative Study Published on 2021-12-222022-09-10 Journal: Nature [Category] COVID19(2023년), MERS, SARS, 변종, 유전자 메커니즘, 진단, [키워드] ACE2 airway Alpha Alpha variant angiotensin assessment B.1.1.7 B.1.351 Beta Beta variant COVID-19 pandemic cultures driver driving enhanced epithelial experiment Experimental models of disease expressing ferret ferrets fitness greater hamster hamsters high viral replication highlight human ACE2 human Angiotensin-converting enzyme in vitro in vivo mechanism mice nasal overcome progenitor receptor Replication respiratory SARS-CoV-2 SARS-CoV-2 variant similar replication kinetics Spike protein Substitution substitutions Support the spike protein Transmission upper respiratory tract variant variants of concern Viral viral infection virus VoC VOCs [DOI] 10.1038/s41586-021-04342-0 PMC 바로가기 [Article Type] Comparative Study
A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilising immunity against SARS-CoV-2 infectionArticle Published on 2021-11-302022-10-04 Journal: NPJ Vaccines [Category] 치료기술, [키워드] abrogated addition antibody B.1.1.7 B.1.351 BCG Blood Cell circulating correlated COVID-19 COVID-19 vaccine cytokine release detectable disease effective Experimental models of disease follicular heterologous vaccine Immunity immunostimulatory Inflammation K18-hACE2 mice Local lung Lymph node mice NAbs plasma B cell promoted PROTECT protective immunity Protein vaccines provide regimen responses SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 neutralising antibody SARS-CoV-2 spike antigen SARS-CoV-2 variant SARS-CoV-2 variants single dose T cells trimeric tuberculosis vaccine vaccination Vaccine virus Virus-specific IgG [DOI] 10.1038/s41541-021-00406-4 PMC 바로가기 [Article Type] Article
Biomarkers of cellular aging during a controlled human malaria infection인간 말라리아 감염 중 세포 노화의 바이오마커Article Published on 2021-09-212024-08-08 Journal: Burma Med J [Category] 말라리아, [키워드] Experimental models of disease Infectious diseases Parasitology Predictive markers [DOI] 10.1038/s41598-021-97985-y PMC 바로가기 [Article Type] Article
SARS-CoV-2 crosses the blood–brain barrier accompanied with basement membrane disruption without tight junctions alterationSARS-CoV-2는 밀착 접합 변경 없이 기저막 파괴와 함께 혈액-뇌 장벽을 통과합니다.Article Published on 2021-09-062022-09-10 Journal: Signal Transduction and Targeted Therapy [Category] Fulltext, SARS, 치료기술, 치료제, [키워드] accompanied Activation administration astrocytes basement membrane blood-brain barrier Blood–brain barrier Brain brains collagen cross Endothelial cell endothelial cells Evan Evans blue Evidence Experimental models of disease expression hACE2 hamster Human in vitro in vivo experiments infect Inflammatory factor inflammatory factors Inflammatory response Inflammatory responses K18-hACE2 transgenic mice marker membrane MMP9 not altered occludin occurred pathway perivascular permeability reported SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA tight junction tight junctions transcellular pathway ultrastructure upregulated Vascular Vasculitis vessel was increased ZO-1 [DOI] 10.1038/s41392-021-00719-9 PMC 바로가기 [Article Type] Article