Fostering compliance with physical distancing by interactive feedback in the context of the COVID-19 pandemic: A web-based randomized controlled trialResearch article Published on 2022-04-012022-10-05 Journal: Internet Interventions [Category] 임상, [키워드] Analysis Anxiety changes in Compliance conducted Containment measure control group COVID-19 Effect Evidence experiment experimental group Exploratory analysis Factor feedback Future help hygiene Infection Infectious disease information Intervention measure Measures objective pandemic participant physical distancing predicted Predictive Prevent prevention prevention of COVID-19 preventive measures Quantitative Randomized controlled trial receiving recognize reduced Result significantly higher Spread spread of COVID-19 subject tested Validity Visualization [DOI] 10.1016/j.invent.2022.100545 [Article Type] Research article
Fulminant and Non-fulminant Clinical COVID-19 Myocarditis in the New York City Area in 2020Observational Study Published on 2022-03-082022-10-05 Journal: Annals of Global Health [Category] 임상, [키워드] Area Atrial fibrillation Characteristics clinical Clinical course clinically complication of COVID-19 Coronary artery disease COVID-19 cross-sectional D-dimer defined Diagnosis echocardiographic Elevation Exploratory analysis ferritin fulminant generate geometric hypothese increasingly Inflammatory marker Isolation Laboratory Laboratory testing limitations Logistic regression MRI myocarditis New York City offer Patient patients precautions presenting symptoms required resource severity severity of COVID-19 significantly higher stratified Student T-test supplemental oxygen systemic inflammation to define ventricular while [DOI] 10.5334/aogh.3583 PMC 바로가기 [Article Type] Observational Study
Effect of a single high dose of vitamin D3 on cytokines, chemokines, and growth factor in patients with moderate to severe COVID-19Randomized Controlled Trial Published on 2022-03-042022-10-05 Journal: The American journal of clinical nutrition [Category] SARS, 임상, [키워드] 25-hydroxyvitamin D acute-phase reactants age assigned BMI Brazil chemokines Concentration COVID-19 cytokine Cytokines dose double-blind Effect endothelial estimating equation exploratory Exploratory analysis Generalized GM-CSF growth factor High dose hospital hospitalized patient IFN-γ IL-10 IL-12p70 IL-17A IL-1β IL-4 IL-6 IL-8 immune immune response Inflammation Inflammatory interaction effect IP-10 leukocyte Macrophage male MCP-1 MIP-1β moderate modulating monocyte chemoattractant protein-1 multicenter not significant outcomes Patient patients with moderate Placebo placebo-controlled postintervention Primary outcome randomized clinical trial Randomly randomly assigned patients receive recruited Registered repeated measures SARS-CoV-2 secondary outcome serum severe coronavirus disease severe COVID-19 significant effect single dose Support TNF-α Trial Vascular VEGF Vitamin D were assessed were used [DOI] 10.1093/ajcn/nqab426 PMC 바로가기 [Article Type] Randomized Controlled Trial
Prognostic and Predictive Biomarkers in Patients With Coronavirus Disease 2019 Treated With Tocilizumab in a Randomized Controlled Trial무작위 대조 시험에서 토실리주맙으로 치료된 2019 코로나바이러스 질환 환자의 예후 및 예측 바이오마커Clinical Trial Published on 2022-03-012022-09-11 Journal: Critical Care Medicine [Category] MERS, SARS, 바이오마커, 임상, 진단, [키워드] (interleukin-6 additional sensitivity analyses Analysis antibody assigned binomial Biomarker Biomarkers C-reactive protein candidate Clinical outcome clinical outcomes clinical status Controlled coronavirus disease Coronavirus disease 2019 COVACTA D-dimer death dimer double-blind Effect Europe evaluated Exploratory analysis ferritin ferritin level hospital discharge Hospitalized Interaction interleukin interleukin-6 Lactate lactate dehydrogenase Lymphocytes measurement mechanical ventilation modeling Monocytes Mortality multicenter Multiple Neutrophils North America observational study Ordinal Scale outcome Patient patients hospitalized phase 3 trial Placebo placebo-controlled Platelets Pneumonia Predictive Predictive value prognostic randomization Randomized Randomly receiving receptor retrospective seven-category ordinal scale severe coronavirus disease standard care Tocilizumab treatment with tocilizumab Trial were measured [DOI] 10.1097/CCM.0000000000005229 PMC 바로가기 [Article Type] Clinical Trial
Very low levels of remdesivir resistance in SARS-COV-2 genomes after 18 months of massive usage during the COVID19 pandemic: A GISAID exploratory analysisCOVID19 전염병 동안 18개월 동안 대량 사용 후 SARS-COV-2 게놈에서 매우 낮은 수준의 렘데시비르 내성: GISAID 탐색 분석Article Published on 2022-02-012022-09-11 Journal: Antiviral Research [Category] COVID19(2023년), SARS, 신약개발, 치료제, [키워드] Analysis Antiviral Antiviral compound Antiviral compounds controlled trials COVID-19 COVID19 E802D Efficacy effort Emergency use authorization Exploratory analysis fitness Frequency Genome GISAID GISAID database hospitalized patients In vitro studies in vivo inhibitor massive molnupiravir mutations Nsp12 pandemic Randomized controlled trial Randomized controlled trials RdRP RdRp mutation RdRp mutations Remdesivir resistance reveal RNA RNA-dependent RNA polymerase SARS-CoV-2 SARS-CoV-2 sequencing Strains Viral RNA viral RNA-dependent RNA polymerase [DOI] 10.1016/j.antiviral.2022.105247 PMC 바로가기 [Article Type] Article
Evaluation of an Optical Defocus Treatment for Myopia Progression Among Schoolchildren During the COVID-19 PandemicResearch Published on 2022-01-142022-10-29 Journal: JAMA Network Open [Category] Coronavirus, SARS, [키워드] age Analysis analyzed association baseline caused cohort study covariates COVID-19 COVID-19 pandemic COVID-19–related lockdown Cycloplegic deviation exploratory Exploratory analysis exposure finding groups Hong Kong Importance independent involved less lockdown longitudinal study measure Measures myopia objective optical participant performed Point progressed progression reducing Relevance Result setting significant interaction significantly significantly more single vision Treatment was normalized was performed were measured worsening [DOI] 10.1001/jamanetworkopen.2021.43781 PMC 바로가기 [Article Type] Research
The Predictive Value of Cell Blood Count Parameters to Diagnose Pulmonary Embolism in Patients with SARS-CoV-2 Infection: A Case Control StudyArticle Published on 2022-01-042022-10-27 Journal: Antibiotics [Category] COVID-19, [키워드] acute pulmonary embolism Analysis angio Biomarker Blood case control study CBC Cell Clinical practice Computed tomography conducted Control coronavirus coronavirus infectious disease-2019 correlation count COVID-19 COVID-19 patient COVID-19 patients diagnostic Embolism excluded Exploratory analysis hospitalised incidence Infection investigated Lymphocyte count material mean platelet volume Mortality mortality rate neutrophil Neutrophil-to-lymphocyte ratio NLR parameter Patient Platelet platelet-to-lymphocyte ratio Population predictor Prognosis prognostic biomarker pulmonary Pulmonary Scintigraphy Result SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome-coronavirus 2 significant difference Univariate analysis value Volume [DOI] 10.3390/antibiotics11010060 PMC 바로가기 [Article Type] Article
Maternal Mental Health under COVID-19 Pandemic in ThailandArticle Published on 2021-12-292022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] 95% CI activities during lockdown activity adjusted affecting Analysis collected conducted continuous monitoring COVID-19 COVID-19 pandemic Critical cross-sectional survey daily living demonstrated effective response example Exploratory analysis Final Health Service identify illness experiences Impact increase in Infant Linear regression lockdown lockdown impacts Maternal Maternal mental health measure medication mental health mental health problems mother multivariable Numerous participant platform positive questionnaire Relaxation technique reported significantly Stress utility variable was performed [DOI] 10.3390/ijerph19010347 PMC 바로가기 [Article Type] Article
Tuberculosis forecasting and temporal trends by sex and age in a high endemic city in northeastern Brazil: where were we before the Covid-19 pandemic?브라질 북동부의 고기병 도시에서 성별과 나이에 의한 결핵 예측 및 시간 경향 : 우리는 Covid-19 Pandemic 이전에 우리는 어디에 있었습니까?Research Published on 2021-12-182022-09-10 Journal: BMC Infectious Diseases [Category] SARS, 치료기술, [키워드] age ARIMA average both sexes Brazil carried characterized city composed COVID-19 COVID-19 pandemic disease Ecological studies Endemic Epidemiology Evidence evidenced Exploratory analysis Health Organization incidence linear men moving average Nursing pandemic progression reported Result resulting Sex stability step the disease Time series studies Tuberculosis was performed were used women World Health Organization [DOI] 10.1186/s12879-021-06978-9 PMC 바로가기 [Article Type] Research
Risk-focused differences in molecular processes implicated in SARS-CoV-2 infection: corollaries in DNA methylation and gene expressionSARS-CoV-2 감염과 관련된 분자 과정의 위험 중심적 차이: DNA 메틸화 및 유전자 발현의 결과Research Published on 2021-12-112022-09-11 Journal: Epigenetics & Chromatin [Category] SARS, 유전자 메커니즘, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Air pollutants airway epithelia Analysis ARRB2 association Asthma autosomal Bronchoalveolar lavage CA5B candidate gene changes in chronic conditions chronic obstructive COMT conducted COPD coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 susceptibility CpG data set Diagnosis diesel exhaust DNA methylation downloaded epithelia exaggerated immune response exhibited explain Exploratory analysis exposure to Factor female Gene Expression gene expression patterns Genes GEO GPX1 Health highlight HS6ST2 immune genes imperative implicated inactivation increased risk individual Infection infections investigated involved loci lung magnitude male molecular molecular association molecular associations molecular basis molecular pattern molecular patterns mRNA expression nasal Nicotine nicotine dependence nitrogen nitrogen dioxide NLRP2 outcomes portal PRIM2 profile Repository respiratory Respiratory conditions Respiratory disease respiratory tissue Result risk risk factor Risk factors SARS-CoV-2 SARS-COV-2 infection second severe acute respiratory syndrome Coronavirus Sex Sex difference Smokers smoking suggested supplementary material susceptibility TATDN1 the disease TLE1 understanding Variation while Whole blood X-linked X-linked gene [DOI] 10.1186/s13072-021-00428-1 PMC 바로가기 [Article Type] Research