Extracellular matrix
[대역어] 세포외 기질
[용어속성] Term
[용어속성] Term
Diffuse alveolar damage patterns reflect the immunological and molecular heterogeneity in fatal COVID-19
Research article
[키워드] alveolar damage
Analysis
Autopsy
Bacteria
Candida parapsilosis
CD8+ T cells
CD8+T cells
Cell
changes in
complex
correlated
COVID-19
COVID-19 case
COVID-19 patients
DAD
diffuse
Diffuse alveolar damage
disease
eight
elevated
enriched pathway
exhibit
Extracellular matrix
Factor
fatal COVID-19
feature
fibroblasts
finding
foundation
funding
fungi
heart
heterogeneity
histological
humoral
immune
immune cells
immunohistochemistry
immunological
immunopathology
implication
innate immune response
Lung disease
lung tissue
Lungs
Macrophage
macrophages
management
Melinda Gate
modulate
molecular
multiplex
occur
Patient
performed
progression
quantified
Regeneron Pharmaceuticals
response
SARS-CoV-2
Secondary infection
subsequent
Support
Swedish
the disease
Transcriptome
Treatment strategies
[DOI] 10.1016/j.ebiom.2022.104229 [Article Type] Research article
[DOI] 10.1016/j.ebiom.2022.104229 [Article Type] Research article
Tuning immunity through tissue mechanotransduction
Reviews
[키워드] adaptive immune system
addition
Alter
arising
biochemical
Cell
cell activation
cellular
change
changes in
conditions
cytokine production
disease
Extracellular matrix
function
Immune cell
immune cells
immune regulation
immune response
Immunity
Infection
Inflammatory response
inflammatory state
Injury
metabolism
multiple pathway
pathway
proliferation
regulate
response
tissue
tissue microenvironment
tuning
[DOI] 10.1038/s41577-022-00761-w [Article Type] Reviews
[DOI] 10.1038/s41577-022-00761-w [Article Type] Reviews
Differences and similarities in endothelial and angiogenic profiles of preeclampsia and COVID-19 in pregnancy
임신 중 자간전증 및 COVID-19의 내피 및 혈관 신생 프로파일의 차이 및 유사성
Article
[키워드] absence
activate
addition
Adhesion Molecule
alteration
Analysis
Angiogenesis
angiogenic factors
angiopoietin
Antigen
Biomarker
Biomarkers
C5b9
Cell
cell membrane
cell membranes
Cell signaling
change
changes in
circulating
Coagulation
Coagulopathy
component
Concentration
Control
controls
COVID-19
COVID-19 infection
COVID-19 patients
Culture
demonstrated
difference
differential diagnosis
differentiation
disease
disorder
endothelial
Endothelial cell
endothelial cells
endothelial damage
Endothelial dysfunction
evaluated
exhibited
expected
explained
expression
Extracellular
Extracellular matrix
group
growth
growth factor
healthy
heparan sulfate
hypertensive
hypertensive disorders of pregnancy
Immunoblots
immunofluorescence
in some
in vitro
increase in
Infection
Inflammation
inflammatory signaling
innate immune response
intercellular
intercellular adhesion molecule
less
lysate
lysates
Mild
mitogen-activated protein kinase
Necrosis
neutrophil
Neutrophil extracellular trap
Neutrophil extracellular traps
normotensive
overexpression
Pathways
Patient
Phosphorylation
placental
placental growth factor
preeclampsia
Pregnancy
pregnant women
Principal component
principal component analysis
profile
profiles
Protein
protein kinase
receptor
reduced
reduction
reduction in
SARS-CoV-2
sera
severe COVID-19
severe COVID-19 patient
signaling pathway
significant increase
significantly increased
Signs and symptoms
similarity
soluble fms-like tyrosine kinase-1
soluble tumor necrosis factor-α receptor I
Spectrum
statistical analysis
statistically
Study design
sulfate
Symptom
Tumor
tumor necrosis
tumor necrosis factor-α
tyrosine
variable
variance
vascular cell adhesion
von Willebrand disease
von Willebrand factor
with COVID-19
women
[DOI] 10.1016/j.ajog.2022.03.048 PMC 바로가기 [Article Type] Article
[DOI] 10.1016/j.ajog.2022.03.048 PMC 바로가기 [Article Type] Article
Possible Role of Matrix Metalloproteinases and TGF-β in COVID-19 Severity and Sequelae
COVID-19 중증도 및 후유증에서 기질 금속단백분해효소 및 TGF-β의 가능한 역할
Review
Published on
Journal: Journal of interferon & cytokine research : the of [Category] COVID19(2023년), SARS, 바이오마커,
Journal: Journal of interferon & cytokine research : the of [Category] COVID19(2023년), SARS, 바이오마커,
[키워드] acute respiratory syndrome
acute respiratory syndrome coronavirus
acute respiratory syndrome coronavirus-2
analyzed
Antiviral agents
ARDS
available data
Biomarker
Biomarkers
Clinical features
clinical form
complex interplay
convalescence
convalescent COVID-19 patients
coronavirus disease
Coronavirus disease 2019
Coronavirus-2
COVID-19
COVID-19 pathogenesis
cytokine
Cytokines
death
Diagnosis
ECM
elicited
exacerbated
Extracellular matrix
Factor
fibrosis
growth
hallmark
immune response
immune responses
Immunity
immunological
implication
Infection
Inflammation
knowledge
Lungs
mandatory
Manifestations
matrix
matrix metalloproteinase
matrix metalloproteinases
MMPs
molecular
other respiratory infection
other respiratory infections
paradox
Participation
pathobiology of COVID-19
Prognosis
provide
pulmonary fibrosis
reduce
remark
required
Research
respiratory
respiratory infections
role
SARS-CoV-2
sequela
serological
Severe acute respiratory syndrome
severe acute respiratory syndrome Coronavirus
severe acute respiratory syndrome coronavirus-2
severe COVID-19
TGF-β
the disease
therapeutic target
therapeutic targets
therapy
tissue injury
transforming growth factor
Treatment
wound healing
[DOI] 10.1089/jir.2021.0222 PMC 바로가기 [Article Type] Review
[DOI] 10.1089/jir.2021.0222 PMC 바로가기 [Article Type] Review
Targeting of Glycosaminoglycans in Genetic and Inflammatory Airway Disease
유전 및 염증성 기도 질환에서 글리코사미노글리칸의 표적화
Review
[키워드] addition
airway
alveolar epithelium
Asthma
Cell
cell differentiation
chronic obstructive
chronic obstructive pulmonary disease
contribute
COVID-19
COVID-19 pandemic
cystic fibrosis
described
Diseases
ECM
Endothelium
Extracellular matrix
fibrosis
glycosaminoglycan
glycosaminoglycans
Immune cell
infiltration
Inflammation
Inflammatory
Interaction
interstitial
involved
lung
Migration
molecular interaction
pathology
pathophysiological role
pulmonary disease
receptor
Research
Respiratory disease
targeting
therapeutic agents
tissue
wound healing
[DOI] 10.3390/ijms23126400 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/ijms23126400 PMC 바로가기 [Article Type] Review
Weighted Gene Co-Expression Network Analysis to Identify Potential Biological Processes and Key Genes in COVID-19-Related Stroke
COVID-19 관련 뇌졸중의 잠재적 생물학적 과정 및 주요 유전자를 식별하기 위한 가중 유전자 공동 발현 네트워크 분석
Article
[키워드] Analysis
Biological
biological processe
Cell
coronavirus disease
COVID-19
Critical
Cytoscape
Cytoscape software
cytosolic
database
dataset
datasets
elevated
enrichment analysis
Extracellular matrix
FIVE
Functional enrichment analysis
gene co-expression network
Gene Expression Omnibus
Gene ontology
Genes
GEO
hub genes
identify
indicated
integrin
integrin signaling
Interaction
Intervention
involved
ITGA2B
ITGB3
KEGG
Kyoto
Lineage
network
pathway
Pathways
PI3K
PI3K-Akt signaling
Platelet
platelet activation
Potential
receptor
Research
screened
stroke
target
was used
[DOI] 10.1155/2022/4526022 PMC 바로가기 [Article Type] Article
[DOI] 10.1155/2022/4526022 PMC 바로가기 [Article Type] Article
Fibronectin as a Marker of Disease Severity in Critically Ill COVID-19 Patients
중환자 COVID-19 환자의 질병 중증도 지표로서의 피브로넥틴
Article
[키워드] Alter
APACHE II
Bacterial
Bacterial sepsis
Biomarker
Biomarkers
can be used
cellular
clinical setting
clinical settings
correlated
COVID-19
COVID-19 patient
COVID-19 patients
COVID-19 sample
COVID-19 samples
Critically ill
Critically ill patient
critically ill patients
disease severity
ELISA
etiology
expression of gene
Extracellular matrix
Fibronectin
form
help
Ill
immune response
immunoblotting
Infection
Intensive
intensive care
intensive care unit
knowledge
MONITOR
Mortality
mortality prediction
no significant difference
no significant differences
Non-survivors
outcomes
Patient
plasma
predict
Proteins
proteolytic
Research
SARS-CoV-2 virus
Sepsis
significantly higher
SOFA scores
treated
Treatment
Treatment outcome
Viral
was related
were measured
[DOI] 10.3390/cells11091566 PMC 바로가기 [Article Type] Article
[DOI] 10.3390/cells11091566 PMC 바로가기 [Article Type] Article
Oral hymecromone decreases hyaluronan in human study participants
경구 hymecromone은 인간 연구 참가자의 hyaluronan을 감소시킵니다
Clinical Trial
[키워드] 4-methylumbelliferone
Accelerator
Administered
Adults
analyzed
animal models
approved
approved drugs
Arm
asked
baseline
breath
catalyst
Concentration
conducted
COVID-19 infection
decrease
dose
dose-dependent manner
doses
drug concentration
Europe
exposure to
Extracellular matrix
fibrosis
glycosaminoglycan
greater
greater decrease
healthy
hymecromone
hypertension
implicated
in vitro
Inflammation
inhibit
inhibitor
Medicine
metabolite
NIH
Open-label
oral
other diseases
Pathogenesis
pathophysiology
pulmonary disease
pulmonary diseases
pulmonary fibrosis
pulmonary hypertension
reduction in
serum
significant decrease
single-center
sputum
Stanford
study participant
subject
therapy
Tolerability
Treatment
[DOI] 10.1172/JCI157983 PMC 바로가기 [Article Type] Clinical Trial
[DOI] 10.1172/JCI157983 PMC 바로가기 [Article Type] Clinical Trial
Targeting inflammation with collagen
콜라겐으로 염증 표적화
Article
[키워드] anti-inflammatory effect
approach
Autoimmune disease
caused
collagen
COVID-19
Degradation
disease severity
ECM
ENhance
explain
Extracellular matrix
IMPROVE
include
Infection
Inflammation
Inflammatory diseases
knowledge
mechanism
MMPs
paper
peptides
polymerised
potential mechanism
potential therapeutic target
reduce
residual risk
Side effect
targeting
tissue
tissue damage
Trigger
type I
[DOI] 10.1002/ctm2.831 PMC 바로가기 [Article Type] Article
[DOI] 10.1002/ctm2.831 PMC 바로가기 [Article Type] Article