Reduction of Infusion Time Using a 10% Intravenous Immunoglobulin Formulation With a 15-Minute Rate Escalation Protocol During Staffing Shortages Due to COVID-19Article Published on 2022-11-012022-11-15 Journal: Journal of infusion nursing : the official publica [Category] 진단, [키워드] Analysis changed condition conducted COVID-19 COVID-19 pandemic database decrease dose Escalation evaluated facilitate faster Formulation home infusion Intravenous immunoglobulin IVIG Nurse Patient protocol Rate receiving reduce required retrospective Safe the mean time Treatment Trial [DOI] 10.1097/NAN.0000000000000488 PMC 바로가기
Pandemic driven innovation: A pilot evaluation of an alternative respiratory pathogen collection deviceArticle Published on 2022-11-012022-11-16 Journal: The American journal of emergency medicine [Category] SARS, 유전자 메커니즘, [키워드] absence All participant amplification communicable disease COVID-19 demonstrated determine diagnostic enrolled evaluated faster favor feedback fused gold standard identify inhibitor Innovation Interpretation invasive mechanism nasopharyngeal Nasopharyngeal swab nucleic acids participant Patient PCR PCR cycle PCR testing pilot study polymerase chain positive producing real-time reverse transcriptase receiving respiratory respiratory pathogen respiratory virus Result resulting RNase P RNAseP RT-qPCR Self-collection respiratory pathogen device. specimen study participant TaqPath tested threshold [DOI] 10.1016/j.ajem.2022.08.047 PMC 바로가기
Case report: BA.1 subvariant showing a BA.2-like pattern using a variant-specific PCR assay due to a single point mutation downstream the spike 69/70 deletionArticle Published on 2022-10-272022-11-15 Journal: Virology Journal [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] Accuracy Algorithm Amino acid amplification BA.1 BA.4 BA.5 Cluster COVID-19 pandemic database detect diagnostic downstream epidemiological example faster genomic knowledge melting curve analysis Mutation mutations next generation sequencing Next-generation sequencing NGS omicron over overcome PCR PCR assay Point mutation probe SARS-CoV-2 SARS-CoV-2 variant sequence Spain specific mutation Surveillance temperature time-consuming variant Variant-specific PCR. while [DOI] 10.1186/s12985-022-01883-2 PMC 바로가기
Rapid Identification of Drug Resistance and Phylogeny in M. tuberculosis, Directly from Sputum SamplesArticle Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] 바이오마커, 변종, 치료제, [키워드] Accuracy applied approaches clinical sample clinician Complete COVID-19 pandemic Culture deaths described detect Diagnosis diagnostic test disease drug drug resistance drug susceptibility drugs effective Establishing evaluate evaluated faster genetic marker Genetic variant genetics genomic variant helping identification identify infecting Infectious disease information initial Initially molecular molecular test Mutation Mycobacterium Mycobacterium tuberculosis negatively affected Next-generation sequencing NGS phenotypic Phylogenetic phylogenetically Phylogeny protocol Rapid reducing reliability reported resistance responsible resulting Sample sequenced Sequencing sputum Sputum sample sputum samples Stage strain targeted sequencing TB patient the WHO Treatment Tuberculosis was used WGS WHO [DOI] 10.1128/spectrum.01252-22 PMC 바로가기
Sensitivity analysis of rapid antigen tests for the Omicron SARS-CoV-2 variant detection from nasopharyngeal swab samples collected in Santiago of ChileArticle Published on 2022-10-202022-11-15 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Analysis Antigen circulation collected Contagion contagiousness COVID-19 COVID-19 pandemic decrease Detection sensitivity evaluate faster genomic greater Health authority highlight immune evasion increasingly indicate Infection limit Local Mutation nasopharyngeal swab sample NPSs omicron Omicron detection outbreak pandemic pandemic in Chile Patient predominant Prevent rapid antigen test RAT RATs reduce RT-PCR RT-qPCR SARS-CoV-2 SARS-CoV-2 variant sensitivity suggested tested the SARS-CoV-2 virus variant viral amplification Viral load viral loads Viral variants VoC [DOI] 10.3389/fpubh.2022.976875 PMC 바로가기
Sustained seropositivity up to 20.5 months after COVID-19Article Published on 2022-10-132022-11-15 Journal: BMC Medicine [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] absence addition affecting age anosmia/hypogeusia Anti-spike antibodies antibody antibody level Barcelona Beta chest pain circulating Cohort Comorbidity comparable COVID-19 cutaneous symptom Delta Duration duration of symptoms evaluated Factor faster Fever FIVE Frequency Gamma headache Health care Health care worker health care workers Hospitalization Humoral immunity hypertension IgA IgA response IgG IgM Infection initial Kinetics long-lasting multivariable regression models nucleocapsid antigen obesity onset of symptom oxygen supply pandemic participant persistence predominant protective role Reinfection remained responders response SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 spike Seroprevalence smoking Spain STABLE study period subset sustained Tachycardia vaccination variant variants of concern Wuhan [DOI] 10.1186/s12916-022-02570-3 PMC 바로가기
Efficacy of COVID-HIGIV in animal models of SARS-CoV-2 infectionArticle Published on 2022-10-102022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 비임상, 진단, [키워드] acute respiratory syndrome animal model anti-SARS-CoV-2 baseline Body weight loss caused China controls convalescent plasma coronavirus COVID-19 COVID-19 vaccines deaths Efficacy evaluated faster hamster hamsters Hospitalization Human Immunoglobulin intravenous Lung inflammation Lung pathology Lungs mice monoclonal antibody mouse model ongoing trial PBS plasma reduced SARS-CoV-2 SARS-COV-2 infection significantly Spread Support therapeutic option treated Treatment Viral load virus was reduced worldwide pandemic [DOI] 10.1038/s41598-022-21223-2 PMC 바로가기
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillanceArticle Published on 2022-10-072022-11-15 Journal: Science (New York, N.y.) [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 진단, [키워드] acute respiratory syndrome African Beta coronavirus country Delta diagnostics dispersal faster genomes genomic Health heterogeneous nature highlight increase in Infectious disease insight Investment limitation Local pandemic proportions SARS-CoV-2 SARS-CoV-2 epidemic sequence Sequencing Surveillance Threats turnaround time variant virus [DOI] 10.1126/science.abq5358 PMC 바로가기
Development of a high-sensitivity and short-duration fluorescence in situ hybridization method for viral mRNA detection in HEK 293T cellsArticle Published on 2022-10-042022-11-15 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] acute respiratory syndrome addition antibody Antigen applied approach Blood caused Cell Cell culture cells Concentration contagious coronavirus Coronavirus disease 2019 COVID-19 development Diagnosis disease DNA virus effective false-negative False-positive results faster Fluorescence in situ hybridization gold standard HEK 293T HEK 293T cell hepatitis A virus HPV Human immunodeficiency virus human papillomavirus IgM and IgG IMPROVE influenza viruses limitation MERS-CoV Middle East Monkeypox mRNA patients plasmids probe Protein public health reduced respiratory syndrome coronavirus RNA RNA virus RT-PCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 viral Sensitivity and specificity significantly spike Surveillance tissue Treatment virus was increased yielding [DOI] 10.3389/fcimb.2022.960938 PMC 바로가기
Modeling the Effectiveness of Healthcare Personnel Reactive Testing and Screening for the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Omicron Variant Within Nursing HomesArticle Published on 2022-10-032022-11-16 Journal: Clinical Infectious Diseases: An Official Publicat [Category] COVID19(2023년), SARS, 변종, [키워드] acute infection Antigen clearance Concentration coronavirus 2 coronavirus disease COVID-19 evade Factor faster healthcare personnel home Immune escape Immunity impacted index case Infection modeling Nursing nursing homes omicron outbreak outbreak testing positive Prevent provide reduction in representing respiratory SARS-CoV-2 Screening screening testing sensitivity Testing Transmission vaccination variant variants viral shedding [DOI] 10.1093/cid/ciac505 PMC 바로가기