Hyperbaric oxygen for treatment of long COVID-19 syndrome (HOT-LoCO): protocol for a randomised, placebo-controlled, double-blind, phase II clinical trialArticle Published on 2022-11-022022-11-15 Journal: BMJ Open [Category] SARS, 진단, [키워드] approved assessment baseline Blood Cardiology case sery chronic fatigue syndrome chronic inflammation clinical clinical trial cognitive collected common COVID-19 defined domain double-blind dysfunction Effect effective Efficacy endothelial function Ethics evaluate fatigue healthy subject hyperbaric oxygen hypothese immunology IMPROVE Inconclusive independent individual initial institutional review board Long malaise mechanism monitoring board oxygen Oxygen therapy pandemic Patient peer-reviewed performed physical placebo-controlled placebo-controlled clinical trial positive Potential treatment product protocol Quality of life Questionnaires randomised rehabilitation medicine respiratory medicine (see thoracic medicine) secondary endpoint suggested survey Swedish Symptom syndrome the primary endpoint Treatment Trial VASCULAR MEDICINE. [DOI] 10.1136/bmjopen-2022-061870 PMC 바로가기
Genetics of COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome: a systematic reviewArticle Published on 2022-11-012022-11-16 Journal: Annals of Clinical and Translational Neurology [Category] 변종, [키워드] ACE affected Analysis association chemokine cohort study components conditions COVID-19 cytokine signaling Enzymes evolutionary relationship expression fatigue functional annotation Genetic genetic component Genetic variant highlight HLA-A HLA-C HLA-DQA1 HLA-DRB1 immune dysfunction Inflammation investigated Mental Ontology Pathogenesis Pathway analysis Pathways performed physical Protein Proteins receptor signaling significantly similarity Symptoms syndrome systematic review T cell activation TYK2 [DOI] 10.1002/acn3.51631 PMC 바로가기
Prevalence, trajectory over time, and risk factor of post-COVID-19 fatigueArticle Published on 2022-11-012022-11-15 Journal: Journal of psychiatric research [Category] 치료제, [키워드] bootstrap Characteristics Clarifying collected Course COVID-19 COVID-19 severity Depression depressive evaluated fatigue identify independent Intervention mechanism overlapping Patient physical post-COVID fatigue post-COVID syndrome predict predicted predictor Prevalence question rehabilitation remained reported symptom risk factor SARS-CoV-2 SARS-CoV-2. scale severity specific treatment Symptom Symptoms syndrome trajectory worsening [DOI] 10.1016/j.jpsychires.2022.08.008 PMC 바로가기
Immunogenicity and safety of SpikoGen®, an adjuvanted recombinant SARS-CoV-2 spike protein vaccine as a homologous and heterologous booster vaccination: A randomized placebo-controlled trialArticle Published on 2022-11-012022-11-15 Journal: Immunology [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] 95% confidence interval Administered adverse event approved assessment booster booster dose booster vaccination clinical trials Course COVID-19 COVID-19 vaccination COVID-19 vaccine cross-neutralization cross-neutralization. Day double-blind Effect fatigue Heterologous homologous humoral immunogenic immunogenicity incidence injection site pain Local Neutralizing antibodies neutralizing antibody outcome participant Participants Placebo placebo-controlled primary immunogenicity Randomized randomized placebo-controlled trial Recombinant spike protein reported robust Safe Safety safety profile saline placebo SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 variants Serious Adverse Event Serious Adverse Events Seroconversion seroconversion rate shown SpikoGen subunit the placebo group Trial Vaccine was performed [DOI] 10.1111/imm.13540 PMC 바로가기
Post-viral fatigue in COVID-19: A review of symptom assessment methods, mental, cognitive, and physical impairmentReview Published on 2022-11-012023-07-10 Journal: Neuroscience and biobehavioral reviews [Category] COVID19(2023년), [키워드] chronic fatigue syndrome coronavirus fatigue neurologic manifestations neuropsychological tests Physical performance. [DOI] 10.1016/j.neubiorev.2022.104902 PMC 바로가기 [Article Type] Review
Hormonal trends in patients suffering from long COVID symptomsArticle Published on 2022-10-282023-07-09 Journal: Endocrine journal [Category] COVID19(2023년), [키워드] fatigue growth hormone Hypothalamo-pituitary-adrenal (HPA) axis Long COVID Thyroid. [DOI] 10.1507/endocrj.EJ22-0093 PMC 바로가기
Saliva antibody-fingerprint of reactivated latent viruses after mild/asymptomatic COVID-19 is unique in patients with myalgic-encephalomyelitis/chronic fatigue syndromeArticle Published on 2022-10-202022-11-15 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] analyzed Anti-viral anti-viral antibody antibody Antibody Response baseline chronic disease CMV cohorts COVID-19 EBV elevated fatigue healthy donor herpesvirus herpesvirus reactivation HERV HERV-K HHV6A HSV2 IgG immunoassay latent virus majority ME/CFS mechanisms multiplex myalgic encephalomyelitis/chronic fatigue syndrome. nuclear oral mucosa overlap Patient plasma Post-viral fatigue Reactivation retrovirus risk factor Saliva SARS-COV-2 infection shown significantly sustained Symptom syndrome systemically triggered unique viral infection virus virus [DOI] 10.3389/fimmu.2022.949787 PMC 바로가기
Effect of remdesivir post hospitalization for COVID-19 infection from the randomized SOLIDARITY Finland trialArticle Published on 2022-10-182022-11-15 Journal: Nature Communications [Category] 치료제, [키워드] 95% CI benefit confidence interval COVID-19 COVID-19 infection Effect Evidence fatigue Finnish Follow-up Hospitalization hospitalized patients hospitals joint long-COVID Long-term follow-up memory occurred outcome Pain Patient Primary outcome problem Quality of life Randomized randomized trial recruited Remdesivir reported resulting SOC Standard of care survived Symptom Symptoms Trial [DOI] 10.1038/s41467-022-33825-5 PMC 바로가기
Fatigue and Cognitive Dysfunction Are Associated with Occupational Status in Post-COVID SyndromeArticle Published on 2022-10-162023-07-10 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), [키워드] Cognition COVID-19 Depression fatigue occupational status post-COVID syndrome. [DOI] 10.3390/ijerph192013368 PMC 바로가기
Respondent Fatigue Reduces Dietary Diversity Scores Reported from Mobile Phone Surveys in Ethiopia during the COVID-19 PandemicArticle Published on 2022-10-062022-11-16 Journal: The Journal of Nutrition [Category] 비임상, [키워드] assigned collected comparison country COVID-19 COVID-19 pandemic decrease dietary dietary diversity Diversity Effect Ethiopia Ethiopian experiment fatigue FIVE fixed food group groups highlighting Impact information measure Metrics Mobile Older outcome phone survey Primary outcome question Randomized Randomly reported respondent response response fatigue. score secondary survey trade-off Volume were assessed women [DOI] 10.1093/jn/nxac153 PMC 바로가기