Clinical characteristics and outcomes of SARS-Cov-2 B.1.1.529 infections in hospitalized patients and multi-surge comparison in LouisianaArticle Published on 2022-10-212022-11-16 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, [키워드] Admission age analyzed B.1.1.529 Characteristics clinical Clinical outcome cohort analysis Comorbidity contributed COVID-19 pandemic defined determine diagnoses Diagnosis discharge disease severity Factor Features Fewer patient FIVE higher risk hospital Hospitalization hospitalized patient ICU ICU admission Infection less Mortality omicron one way ANOVA outcome outcomes overall mortality Patient peer positive presenting presenting symptom progressed proportion Protective required risk SARS-CoV-2 SARS-CoV-2 test severe disease Sex subsequent subset Symptom the SARS-CoV-2 the United State vaccination variant Ventilation was performed [DOI] 10.1371/journal.pone.0268853 PMC 바로가기
Spectral and theoretical study of SARS-CoV-2 ORF10 protein interaction with endogenous and exogenous macroheterocyclic compoundsSARS-CoV-2 ORF10 단백질과 내인성 및 외인성 거대 이종고리 화합물 상호작용에 대한 스펙트럼 및 이론 연구Article Published on 2022-10-152022-09-11 Journal: Spectrochimica acta. Part A, Molecular and biomole [Category] COVID19(2023년), SARS, 치료제, [키워드] Accessory accessory protein accessory proteins Alpha Antiviral approved bind carried caused cells Chlorin choice complexes Compound coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 criteria drug effective drug effective drugs energy Escherichia coli expressed Features form health problem highest affinity Host immune response in silico infected patient infected patients inhibitor inhibitory initial Interaction macrocycle matter modulate molecular docking MOST ORF10 ORF10 protein Orientation pandemic Pathogenesis Porphyrin Pragmatic precedence Protein protoporphyrin public health recommendation resource SARS-CoV-2 SARS-CoV-2 accessory proteins SARS-CoV-2 coronavirus silico studies Spectral Spectroscopy Spectroscopy. Spread Stage suggested Taking the disease the SARS-CoV-2 Treatment treatment of COVID-19 virucidal virus [DOI] 10.1016/j.saa.2022.121403 PMC 바로가기 [Article Type] Article
Challenges in diagnosing COVID-19 related disease in pediatric patients with rheumatic diseaseArticle Published on 2022-10-152022-11-15 Journal: Modern rheumatology [Category] 진단, [키워드] abdominal pain Administered Anakinra challenge chest pain children clinical Clinical characteristics coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 dermatomyositis diagnosing Diagnosis disease elevated evaluated Features Fever fraction function Immunoglobulin infiltration Inflammatory Inflammatory marker juvenile idiopathic arthritis Laboratory Mediterranean fever Methylprednisolone MIS-C multisystem inflammatory syndrome in children (MIS-C) myalgia outcome overlap Patient patients Pediatric patient Pneumonia raise Rash rheumatic disease Rheumatic diseases Symptom syndrome the patient [DOI] 10.1093/mr/roab112 PMC 바로가기
Severe COVID-19 patients display hyper-activated NK cells and NK cell-platelet aggregatesArticle Published on 2022-10-052022-11-15 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 진단, 치료제, [키워드] absence activated Activation aggregate aggregates analysed antiviral immunity Blood blood cell CD107a CD62P Cell cells changes in chemokines Cohort correlated COVID-19 COVID-19 disease COVID-19 patient cytokine Cytokines Cytometry cytotoxicity discharged disease pathology early stage Ex vivo Features flow cytometry form Frequency gene signature hospital hospitalised hospitalised COVID-19 patient ICU ICU patient IFN-γ IL-15 in vitro increased expression Infection innate immune response intensive care unit killing majority natural Neutrophils NK cell NK cells Patient patients phenotype phenotyped plasma Platelet platelet aggregates. Platelets Post-COVID-19 patients quantified SARS-CoV-2 scRNA-seq severe COVID-19 disease severe symptoms Single-cell RNA-sequencing Stage subset Symptom Symptoms target cells the timing TNF-α viral infections were measured while [DOI] 10.3389/fimmu.2022.861251 PMC 바로가기
COVID-19 malicious domain names classificationResearch article Published on 2022-10-012022-10-05 Journal: Sensors (Basel, Switzerland) [Category] 치료기술, [키워드] approach attack attacks COVID-19 COVID-19 pandemic Cybersecurity develop domain effective feature Features greater Hoeffding trees individual information Internet machine learning machine learning model online learning organizations pandemic Phishing attacks Prevent Protective researcher resources supervised learning website [DOI] 10.1016/j.eswa.2022.117553 [Article Type] Research article
Porphyrinoids coated silica nanoparticles capacitive sensors for COVID-19 detection from the analysis of blood serum volatolomeResearch article Published on 2022-10-012022-10-05 Journal: Sensors and Actuators B: Chemical [Category] 치료기술, [키워드] Accuracy Affect Analysis Blood Capacitive gas sensors coated Compound COVID-19 COVID-19 sample diffusion Diseases Features identify Linear Discriminant Analysis Pathologies Porphyrinoids processed selective sensor serum Silica nanoparticles Variation Volatolomics [DOI] 10.1016/j.snb.2022.132329 [Article Type] Research article
RESCOVIDTCNnet: A residual neural network-based framework for COVID-19 detection using TCN and EWT with chest X-ray imagesResearch article Published on 2022-10-012022-10-05 Journal: Sensors (Basel, Switzerland) [Category] 치료기술, [키워드] Accuracy Algorithm ANN approach Chest chest X-ray Chest X-ray image COVID COVID-19 COVID-19 diagnosis death deep learning diagnose Diagnosis early stage EWT Features filtered healthy controls Patient Pneumonia Pre-trained CNN methods: Inception-V3 & Resnet-50 radiologist Research suggested Support SVM TCN transfer were used X-ray Lung images [DOI] 10.1016/j.eswa.2022.117410 [Article Type] Research article
Deep learning and machine learning-based voice analysis for the detection of COVID-19: A proposal and comparison of architecturesResearch article Published on 2022-10-012022-10-05 Journal: Knowledge-Based Systems [Category] 바이오마커, 진단, 치료기술, [키워드] 1EVowel /e/ vocal task 2SSentence vocal task 3CCough vocal task Accuracy acting AdaBoost adopted Algorithms Analysis applied approach binary Biomarker Biomarkers CFSCorrelation-based Feature Selection Classifier clinically CNN CNNConvolutional neural network collected Convolutional neural network Correlation-based Feature Selection Cough vocal task COVID COVID-19 COVID-19 pandemic COVID-19 positive subjects deep deep learning DLDeep Learning Effect evaluated feature Features forest Healthy control subjects HHealthy control subjects highlight identify independent individual machine learning Mel-frequency Cepstral Coefficients MFCCMel-frequency Cepstral Coefficients MLmachine learning nasal swab NSNasal Swab PCRPolymerase Chain Reaction-based molecular swabs Polymerase Chain Reaction-based molecular swabs positive Positive subjects Positive versus Healthy subjects comparison PPositive subjects PvsHPositive versus Healthy subjects comparison Random forest real time Receiver-Operating Curve Recovered subjects Recovered versus Healthy subjects comparison Rectified Linear Unit ReLuRectified Linear Unit RFRandom Forest ROCReceiver-Operating Curve RRecovered subjects RvsHRecovered versus Healthy subjects comparison selection process Sentence vocal task subject subjects subset support vector machine SVMSupport vector machine Vowel /e/ vocal task [DOI] 10.1016/j.knosys.2022.109539 [Article Type] Research article
Comprehensive analysis of pathways in Coronavirus 2019 (COVID-19) using an unsupervised machine learning methodResearch article Published on 2022-10-012022-10-05 Journal: Applied Soft Computing [Category] 바이오마커, 변종, 신약개발, 유전자 메커니즘, 진단, 치료기술, [키워드] acute respiratory syndrome Analysis approach artificial intelligence assist available data Bioinformatics analysis biological pathway Biomarkers Comprehensive comprehensive analysis coronavirus Coronavirus disease 2019 COVID-19 COVID-19 pathology defined disease dominant effective Features first stage help host cell implementation introduced machine learning material Novel coronavirus pathway Pathway analysis Pathway enrichment analysis Pathways researcher SARS-CoV-2 selected Signaling target Treatment unsupervised learning WHO World Health Organization worldwide crisis [DOI] 10.1016/j.asoc.2022.109510 [Article Type] Research article
Antimicrobial peptides: features, applications and the potential use against covid-19Article Published on 2022-10-012022-11-16 Journal: Molecular biology reports [Category] 변종, [키워드] accelerated addition AMP AMPs Antibiotics antimicrobial antimicrobial peptides APD Bacteria biosynthesis pathway Cancer cells cationic clinical trial conserved COVID-19 demonstrated develop drugs Evolution Features functional fungi Innate immunity mechanism mechanisms peptide provide specificity therapeutic therapeutic agents Toxicity unique variants viral infectivity viruses [DOI] 10.1007/s11033-022-07572-1 PMC 바로가기