Predictors of COVID-19 disease severity augment the Braden scale in the prediction of pressure ulcer development among COVID-19–positive intensive care unit patients: A case-control studyShort communication Published on 2022-09-012022-10-05 Journal: Journal of the American Academy of Dermatology [Category] 바이오마커, [키워드] BMI Braden scale case-control study COVID-19 COVID-19 disease severity D-dimer fibrinogen intensive care Predictive model pressure ulcer Risk factors [DOI] 10.1016/j.jaad.2022.01.021 [Article Type] Short communication
Remdesivir Plus Dexamethasone Versus Dexamethasone Alone for the Treatment of Coronavirus Disease 2019 (COVID-19) Patients Requiring Supplemental O2 Therapy: A Prospective Controlled Nonrandomized Study코로나바이러스 질병 2019(COVID-19) 환자 치료를 위한 렘데시비르 플러스 덱사메타손 대 덱사메타손 단독 요법: 보충 O2 요법이 필요한 환자: 전향적 통제된 비무작위 연구Controlled Clinical Trial Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 임상, 치료제, [키워드] 30-Day mortality Antiviral baseline calculated clinical outcomes cohorts Combination Controlled coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient CRP D-dimer Dexamethasone drug effective Endpoint enrolled evaluate evaluated faster fibrinogen FiO2 group groups Hospitalization IMPROVE independent Inflammatory inflammatory markers Kaplan-Meier Kaplan-Meier curve Kaplan-Meier curves laboratory characteristics log-rank test median Mortality neutrophil neutrophil/lymphocyte ratio no differences occurred primary endpoint primary endpoints Prospective reducing mortality reduction in reduction in mortality Remdesivir Respiratory failure Respiratory function Sample size SARS-CoV-2 clearance secondary Secondary endpoints shown significant difference significant differences survival the log-rank test therapy treat Treatment viral clearance Viral clearance. were used [DOI] 10.1093/cid/ciac014 PMC 바로가기 [Article Type] Controlled Clinical Trial
SARS-CoV-2 infection induces soluble platelet activation markers and PAI-1 in the early moderate stage of COVID-19SARS-CoV-2 감염은 COVID-19의 초기 중등도 단계에서 가용성 혈소판 활성화 마커 및 PAI-1을 유도합니다Article Published on 2022-08-012022-09-11 Journal: International journal of laboratory hematology [Category] MERS, SARS, 바이오마커, [키워드] activated activated partial thromboplastin time activation of platelet activation of platelets Analysis aPTT CD40 ligand Coagulation coagulation dysfunction coagulation factor Coagulation factors Coagulation system coagulation test coagulation tests Comorbidity correlated COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity D-dimer dysfunction dysregulated elevated Factor fibrinogen flow cytometry FXIII help hospitalized COVID-19 patient hospitalized COVID-19 patients induce inhibitor intensive care limit marker moderate Moderate COVID-19 molecular Multiplex assay P-selectin partial thromboplastin time Pathogenesis pathogenesis of COVID-19 pathway performed plasma plasminogen Platelet platelet activation Platelets Pneumonia progression prothrombin Prothrombin time recruited reduction in required SARS-COV-2 infection severe cases severe COVID-19 severe patients severity significantly Stage TFPI the disease Thromboembolism THROMBOPLASTIN Thromboprophylaxis tissue Tissue Factor tissue factor pathway inhibitor tissue plasminogen activator tissue plasminogen activator. [DOI] 10.1111/ijlh.13829 PMC 바로가기 [Article Type] Article
Evaluation of a potential prognostic parameter for the inflammatory status in COVID-19 patients: The inflammatory protein ratioCOVID-19 환자의 염증 상태에 대한 잠재적인 예후 매개변수 평가: 염증 단백질 비율Article Published on 2022-08-012022-09-11 Journal: Electrophoresis [Category] COVID19(2023년), SARS, 치료기술, [키워드] albumin all the patients ANOVA C-reactive protein calculated Chain Reaction controls coronavirus disease Coronavirus disease 2019 correlation COVID-19 COVID-19 patient CRP D-dimer dimer fibrinogen Globulin hospitalized patient Human plasma immuno-turbidimetric assay immunoassay Inflammatory inflammatory protein inflammatory state inflammatory status Interpretation involved Kruskal-Wallis mathematical Nasopharyngeal swab nasopharyngeal swabs parameter parameters Pearson performed polymerase chain polymerase chain reaction prognostic proportionality Protein qualitative test quantified real time real time Polymerase Chain Reaction RNA RT-PCR SARS-CoV-2 SARS-CoV-2 positivity separated Serum protein serum protein electrophoresis. serum proteins Significant significantly Spearman the patient unique variance [DOI] 10.1002/elps.202100396 PMC 바로가기 [Article Type] Article
Coagulation parameters abnormalities and their relation to clinical outcomes in hospitalized and severe COVID-19 patients: prospective study Research Published on 2022-08-012022-10-05 Journal: Scientific Reports [Category] 바이오마커, 임상, 치료법, [키워드] abnormality activated biochemical biochemical parameter clinical Clinical outcome Coagulation coagulation parameter Coagulation parameters Concentration COVID-19 COVID-19 patient COVID-19 severity cut-off D dimer D-dimer death diagnosed difference Dyspnea enrolled fibrinogen hematological Hospitalized inflammatory markers LDH non-severe group Older outcome parameter parameters Partial Patient patients Predictive Prospective Study prothrombin risk Sensitivity and specificity severe COVID-19 severe group Severe patient severity severity of COVID-19 survival the patient time were recorded [DOI] 10.1038/s41598-022-16915-8 [Article Type] Research
COVID-19-associated pulmonary aspergillosis is associated with increased in-hospital mortality and prolonged SARS-CoV-2 viral sheddingResearch article Published on 2022-08-012022-10-05 Journal: Journal of the Formosan Medical Association = Taiw [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] 95% confidence interval acute respiratory syndrome adjusted odds ratio Analysis analyzed Asian Aspergillus CAPA clinical factor coronavirus Coronavirus disease 2019 Corticosteroid COVID-19 Critically ill patient Diagnosis enrolled fibrinogen fibrinogen level ICU admission ICUs in-hospital mortality in-hospital mortality rate incidence rate intensive care unit investigated Lower mechanically ventilated patients median time outcomes Patient patients with COVID-19 polymerase chain Population Result reverse transcription SARS-CoV-2 SARS-CoV-2 viral shedding serum Treatment outcome Virus shedding with COVID-19 [DOI] 10.1016/j.jfma.2022.07.006 [Article Type] Research article
A Rational Approach to Coagulation TestingReview Published on 2022-07-042023-07-08 Journal: Laboratory medicine [Category] COVID19(2023년), [키워드] activated partial thomboplastin time Coagulation fibrinogen Platelet count Prothrombin time test selection Viscoelastic testing. [DOI] 10.1093/labmed/lmac005 PMC 바로가기 [Article Type] Review
Clinical and laboratory profiles of the SARS-CoV-2 Delta variant compared with pre-Delta variants델타 이전 변이와 비교한 SARS-CoV-2 Delta 변이의 임상 및 실험실 프로필Article Published on 2022-07-012022-09-11 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 변종, [키워드] activated C-reactive protein can be used Care changes in characteristic Characteristics characterized clinical Clinical data Cohort Comorbidities comparison Comparisons COVID-19 defined Delta delta variant Department Descriptive statistics ferritin fibrinogen genomic Genomics Gradient Gradient boosting model heterogeneous hospitalizations hospitalized patients Human identify implication Inflammatory intensive care intensive care unit International international normalized ratio Laboratory laboratory characteristics Lactate lactate dehydrogenase machine machine learning machine learning approach machine learning approaches Negative predictive value normalized Patient peaked phenotypical Positive predictive value Predictive value profile prothrombin Prothrombin time public health measures receiver receiver operating characteristic Research Retrospective study SARS-CoV-2 variant SARS-CoV-2 variants sensitivity service single-center specificity supported the SARS-CoV-2 the United State THROMBOPLASTIN Transmissibility Treatment protocol United States variant variants variants of concern. virulence Wave Waves were used [DOI] 10.1016/j.ijid.2022.04.050 PMC 바로가기 [Article Type] Article
Serum homocysteine level in pediatric patients with COVID-19 and its correlation with the disease severity소아 코로나19 환자의 혈청 호모시스테인 수치와 질병 중증도와의 상관관계Article Published on 2022-07-012022-09-11 Journal: Pediatric pulmonology [Category] MERS, 바이오마커, [키워드] acute infection Admission adult COVID-19 patients Adults Alanine Alanine transaminase aspartate Aspartate transaminase Biomarker Biomarkers Blood urea nitrogen children children with COVID-19 Complication conducted Control coronavirus disease Coronavirus disease 2019 correlated correlation COVID-19 COVID-19 patient cross-sectional cross-sectional study D-dimer detect disease severity Embolism enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay ferritin fibrinogen fibrinogen degradation product fibrinogen degradation products healthy control homocysteine homocysteine. increase in intensive care interquartile range Laboratory median nitrogen parameter patients pediatric Pediatric patient Pediatric patients pediatrics positive correlation prothrombin Prothrombin time prothrombotic radiological Radiological parameters reported risk serum severity severity of COVID-19 speculation statistically significant subjects syndrome the disease thrombosis urea was measured with COVID-19 [DOI] 10.1002/ppul.25920 PMC 바로가기 [Article Type] Article
Current and novel biomarkers of thrombotic risk in COVID-19: a Consensus Statement from the International COVID-19 Thrombosis Biomarkers ColloquiumCOVID-19의 혈전 위험에 대한 현재 및 신규 바이오마커: 국제 COVID-19 혈전증 바이오마커 콜로키움의 합의 성명Review Published on 2022-07-012022-09-11 Journal: Nature reviews. Cardiology [Category] COVID19(2023년), MERS, SARS, 바이오마커, 임상, 치료기술, 치료법, [키워드] Activation aggregation Biomarker Biomarkers Clinical use Coagulation Coagulopathy Consensus coronavirus disease Coronavirus disease 2019 COVID-19 current D-dimer disease disease severity Elevation elevations Endothelial cell excessive inflammation fibrinogen fibrinolysis hypercoagulability in-hospital mortality Injury Intervention marker pandemic Patient patients Platelet platelet activation platelet aggregation platform Post-vaccine predict Prognosis prothrombotic recommendation Research risk risk stratification syndrome thrombocytopenia thromboembolic Thromboembolic events thrombosis thrombotic thrombotic and thromboembolic events thrombotic risk with COVID-19 [DOI] 10.1038/s41569-021-00665-7 PMC 바로가기 [Article Type] Review