filtration rate – Page 2 – Communicable Diseases Research

Study protocol: long-term effect of the New Nordic Renal Diet on phosphorus and lipid homeostasis in patients with chronic kidney disease, stages 3 and 4: a randomised controlled trial

연구 프로토콜: 만성 신장 질환 환자의 인 및 지질 항상성에 대한 New Nordic Renal Diet의 장기 효과, 3단계 및 4단계: 무작위 대조 시험

Article

Published on 2021-08-302022-09-11
Journal: BMJ Open [Category] SARS, 임상,

Low level of plasminogen increases risk for mortality in COVID-19 patients

낮은 수준의 플라스미노겐은 COVID-19 환자의 사망 위험을 증가시킵니다

Article

Published on 2021-08-052022-09-11
Journal: Cell Death & Disease [Category] MERS, 바이오마커, 임상,

[키워드] Activation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis aPTT association Biomarker blood glucose Caucasian patient caused causes Cluster Coagulation complex mechanism complex mechanisms Complication coronavirus coronavirus disease Coronavirus disease 2019 correlated correlation COVID-19 COVID-19 complications COVID-19 patient CRP D-dimer decrease Diagnostic markers dimer expression fasting blood female fibrinolysis filtration rate glomerular filtration rate Glucose IL-6 increase indicated Infection Inflammatory marker inflammatory markers inflammatory parameters INR marker Mortality multidimensional organ dysfunction organ dysfunctions outcome pathophysiology pathway patients with COVID-19 PCT plasminogen precursor Prognosis respiratory risk SARS-CoV-2 severe acute respiratory syndrome Coronavirus significantly therapeutic target These data thromboembolic viral infection
[DOI] 10.1038/s41419-021-04070-3 PMC 바로가기 [Article Type] Article

Low immunogenicity to SARS-CoV-2 vaccination among liver transplant recipients

간 이식 환자 중 SARS-CoV-2 백신 접종에 대한 낮은 면역원성

Article

Published on 2021-08-012022-09-11
Journal: Journal of hepatology [Category] MERS, SARS, 진단, 치료법,

[키워드] age All participant All participants antibody Antibody Response Antibody titer approved average BNT162b2 center Clinical data Control controls COVID-19 COVID-19 infection dose Efficacy elicited enrolled Factor female filtration rate glomerular filtration rate healthy healthy controls healthy volunteer healthy volunteers High dose IgG IgG antibodies Immunity immunogenicity Immunological response immunosuppressive medications include less levels of antibody liver liver transplant Liver transplantation medical records mRNA vaccine mRNA-based vaccine mycophenolate mycophenolate mofetil N-protein nucleocapsid Older age Patient Pfizer Pfizer-BioNTech Pfizer-BioNTech BNT162b2 positive positive serology Prevent receiving recipient recipients regimen renal function reported risk S-protein SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 IgG antibodies SARS-CoV-2 IgG antibody SARS-CoV-2 vaccination SARS-CoV-2 vaccine Serious Adverse Event Serious Adverse Events serological serology Side effect significantly lower Special Population spike-protein steroid Steroids tested the patient Treatment trials vaccination Vaccine vaccine immunogenicity virus was collected
[DOI] 10.1016/j.jhep.2021.04.020 PMC 바로가기 [Article Type] Article

Remdesivir, Renal Function and Short-Term Clinical Outcomes in Elderly COVID-19 Pneumonia Patients: A Single-Centre Study

렘데시비르, 노인 COVID-19 폐렴 환자의 신장 기능 및 단기 임상 결과: 단일 센터 연구

Observational Study

Published on 2021-06-032022-09-11
Journal: Clinical interventions in aging [Category] Coronavirus, MERS, SARS, 임상, 진단, 치료제,

[키워드] acute respiratory syndrome Admission age aging aging patient aging patients Antiviral antiviral agent approved baseline characterized Chronic kidney disease CKD clinical Cohort coronavirus coronavirus 2 COVID-19 Diagnosis discharge drug Drug administration EGFR elderly estimated glomerular filtration rate evaluated filtration rate food Food and Drug Administration function glomerular filtration glomerular filtration rate hospital Hospitalized hospitalized patient hospitalized patients inclusion criteria indications individual inflammatory cascade internal medicine International involved kidney Kidney disease life-threatening observational study participant Patient Pneumonia Prognosis receiving recovered recovered patients reduce Remdesivir renal function renal impairment respiratory retrospective SARS CoV2 Severe acute respiratory syndrome severe renal impairment significantly lower stage III stratified study cohort Treatment variable
[DOI] 10.2147/CIA.S313028 PMC 바로가기 [Article Type] Observational Study

Expression profiles revealed potential kidney injury caused by SARS-CoV-2: a systematic analysis of ACE2 and clinical lessons learned from this discovery

발현 프로필은 SARS-CoV-2로 인한 잠재적인 신장 손상을 나타냈습니다: ACE2의 체계적인 분석 및 이 발견에서 얻은 임상 교훈

Research Paper

Published on 2021-04-302022-09-10
Journal: Aging (Albany NY) [Category] SARS, 유전자 메커니즘, 치료기술,

[키워드] ACE2 ACE2 distribution ACE2 expression ACE2-positive cell ACE2-positive cells acute renal failure Admission Adults Analysis analyzed assessment assessments Blood urea nitrogen cause caused Cell city Clinical findings collected Collecting duct Comorbidities conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 positive patient creatinine Data analysis dataset EGFR elevated epithelial cells estimated glomerular filtration rate Evidence female filtration rate functions glomerular glomerular filtration rate healthy individuals hospital induce Infection infection site kidney kidney damage Kidney function Kidney injury kidney tissue Laboratory laboratory findings males nitrogen novel Novel coronavirus novel coronavirus disease organ organs pathophysiology Patient patients Pneumonia positive cells profile renal failure renal function reported retrospective RNAseq RNAseq data SARS-CoV-2 scRNA-seq data selected sequencing data serum creatinine single-cell Single-cell RNA sequencing systematic analysis the patient the SARS-CoV-2 Transcriptome transcriptome analysis urea urea nitrogen viral loads Wuhan Wuhan, China
[DOI] 10.18632/aging.202224 PMC 바로가기 [Article Type] Research Paper

Development of a severity of disease score and classification model by machine learning for hospitalized COVID-19 patients

입원 중인 코로나19 환자를 위한 머신러닝을 통한 질병 점수 및 분류 모델의 중증도 개발

Research Article

Published on 2021-04-212022-09-10
Journal: PLoS ONE [Category] MERS, SARS, 치료기술,

[키워드] 95% CI 95% confidence interval Admission age applied AUC C-reactive protein calculator Charlson Comorbidity Index clinical and laboratory features Cohort Comorbidity COVID-19 patients detect development died Disease progression efficient estimated glomerular filtration rate evaluated filtration rate FiO2 glomerular filtration rate higher risk hospital Hospital admission Hospitalization Hospitalized hospitalized COVID-19 patient hospitalized COVID-19 patients identify laboratory feature Lymphocytes machine-learning management mechanical ventilation open oxygen oxygen saturation Patient patients performance performed Peripheral blood predict procalcitonin progression required Result risk Sensitivity and specificity severe disease severe disease progression Severity of disease SpO2 stratified tested variable was used were used
[DOI] 10.1371/journal.pone.0240200 PMC 바로가기 [Article Type] Research Article

Classification and analysis of outcome predictors in non-critically ill COVID-19 patients

중증이 아닌 COVID-19 환자의 결과 예측인자의 분류 및 분석

Article

Published on 2021-04-012022-09-11
Journal: Internal medicine journal [Category] SARS, 치료기술,

[키워드] 95% confidence interval Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age analysed Analysis arterial pressure body temperature Care Characteristics classification Clinical outcome clinical outcomes clinical variable consecutive patient coronavirus COVID-19 COVID-19 patient creatinine Critically ill dead Dementia determined by develop discharged Early detection Factor filtration rate followed by fraction glomerular filtration rate hospital intensive care intensive care unit machine learning non-critically ill non-critically ill patient non-critically ill patients outcome oxygen Patient Pordenone predict prediction predictor predictors random Random forest recorded resources serum sodium severe acute respiratory syndrome Coronavirus sodium transferred with COVID-19
[DOI] 10.1111/imj.15140 PMC 바로가기 [Article Type] Article

Early clinical factors predicting the development of critical disease in Japanese patients with COVID-19: A single-center, retrospective, observational study

일본 COVID-19 환자의 중병 발병을 예측하는 초기 임상 요인: 단일 센터, 후향적, 관찰 연구

Observational Study

Published on 2021-04-012022-09-11
Journal: Journal of medical virology [Category] Fulltext, MERS, 바이오마커, 임상,

[키워드] Admission Analysis Asymptomatic characteristic clinical factor clinical factors Comorbidity coronavirus coronavirus disease coronavirus disease-2019 COVID-19 CoVs Cox proportional hazard Cox proportional hazards analysis Critical Critical disease cutoff value disease Disease progression EGFR elevated elevated lactate dehydrogenase enrolled evaluated excluded Factor filtration rate glomerular filtration rate hospital Hospitalized Japanese Japanese patients Laboratory laboratory finding laboratory-confirmed Laboratory-confirmed COVID-19 Lactate lactate dehydrogenase LDH Logistic lymphocytopenia male mechanical ventilation median age median time Mild mild to moderate moderate not significant Patient patients with COVID-19 Pediatric patients progression receiver operating characteristic retrospective risk factor Risk factors significantly single-center statin symptom onset
[DOI] 10.1002/jmv.26599 PMC 바로가기 [Article Type] Observational Study

RAMIC: Design of a randomized, double-blind, placebo-controlled trial to evaluate the efficacy of ramipril in patients with COVID-19

RAMIC: COVID-19 환자에서 라미프릴의 효능을 평가하기 위한 무작위, 이중 맹검, 위약 대조 시험 설계

Article

Published on 2021-04-012022-09-11
Journal: Contemporary clinical trials [Category] MERS, SARS, 바이오마커, 임상,

[키워드] ACE Adult patients angiotensin Complication composite endpoint coronavirus disease Coronavirus disease 2019 COVID-19 death decrease diastolic double-blind Efficacy emergency department Endpoint evaluate exclusion criteria filtration rate glomerular filtration rate hospital ICU admission include Informed consent inhibitor Invasive mechanical ventilation Mechanical mechanical ventilation mechanical ventilator mitigate Mortality multicenter Novel coronavirus novel coronavirus disease occur patients with COVID-19 Personal protective equipment Placebo placebo-controlled trial PPE primary composite endpoint ramipril Randomized receive reduced risk risk risk of infection risk of transmission SARS-CoV-2 transmission SARS-CoV2 shown study population study visit Systolic blood pressure Treatment Virtual visit.
[DOI] 10.1016/j.cct.2021.106330 PMC 바로가기 [Article Type] Article

Comparison of Time to Clinical Improvement With vs Without Remdesivir Treatment in Hospitalized Patients With COVID-19

COVID-19로 입원한 환자에서 렘데시비르 치료를 받은 경우와 없는 경우의 임상 개선 시간 비교

Research

Published on 2021-03-242022-09-10
Journal: JAMA Network Open [Category] SARS, 치료제,

[키워드] 28-day mortality 95% CI acute respiratory syndrome addition adjusted hazard ratio Administered administration Admission Admissions adults hospitalized age Alanine alanine aminotransferase albumin Analysis Baltimore blood cell blood pressure body mass body mass index C-reactive protein Chain Reaction Charlson Comorbidity Index clinical Clinical improvement clinical trial Cohort Combination Comorbidity Complete conducted Control controls coronavirus coronavirus disease Coronavirus disease 2019 Corticosteroid corticosteroid treatment Corticosteroids covariate COVID-19 death deaths decrease did not reduce dimerized Dimerized plasmin fragment D Effectiveness exposure faster filtration rate finding fraction glomerular filtration rate hazard ratio Health Organization health system hospital hospital discharge hospitalized patient hospitalized patients Importance improvement individual individuals infected individual infected individuals Infection interquartile range lymphocyte Lymphocyte count matched controls measure median median age men Mortality mortality rate multicenter objective outcome oxygen oxygen saturation participant Patient patients patients hospitalized Peripheral blood Point polymerase chain polymerase chain reaction Population Primary outcome Propensity score proportion pulse receipt receive recipient reduced Relevance Remdesivir Research respiratory respiratory rate Result retrospective secondary outcome setting severity Sex statistically significant temperature the median Therapies time treated Treatment Washington White blood cell with COVID-19 World Health Organization
[DOI] 10.1001/jamanetworkopen.2021.3071 PMC 바로가기 [Article Type] Research