Online Registry of COVID-19–Associated Mucormycosis Cases, India, 20212021년 인도, COVID-19 관련 점막진균증 사례 온라인 등록Research Letter Published on 2021-11-012022-09-10 Journal: Emerging Infectious Diseases [Category] 변종, [키워드] 2019 novel coronavirus disease analyzed coronavirus coronavirus disease Coronaviruses Corticosteroids COVID-19 delta variant diagnosed drug fungal infections fungi fungus India infections Mucormycosis Patient registry respiratory infections SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 viruses Zinc zinc supplementation zoonoses [DOI] 10.3201/eid2711.211322 PMC 바로가기 [Article Type] Research Letter
Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infectionsReview Published on 2021-10-222023-07-02 Journal: F1000Research [Category] SARS, [키워드] Bacteria COVID-19 fungus Nitrate nitric oxide nitrite Protozoa virus [DOI] 10.12688/f1000research.51270.2 PMC 바로가기 [Article Type] Review
New Tetramic Acid Derivatives From the Deep-Sea-Derived Fungus Penicillium sp. SCSIO06868 With SARS-CoV-2 M pro Inhibitory Activity EvaluationMicrobiology Published on 2021-09-272022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] Penicillium sp. acid activity acute respiratory syndrome Analysis Antibacterial Antiviral antiviral activity Compound coronavirus coronavirus disease Culture deep-sea-derived fungus derivative ECD eight electrospray ionization exhibited fungus High-resolution inhibitory activity inhibitory concentration M pro New NMR nuclear optical pandemic Penicillium protease reported responsible SARS-CoV-2 secondary metabolites selective Staphylococcus aureus Structure X-ray crystallography [DOI] 10.3389/fmicb.2021.730807 PMC 바로가기 [Article Type] Microbiology
Anti-Inflammatory, Antiallergic, and COVID-19 Main Protease (M pro ) Inhibitory Activities of Butenolides from a Marine-Derived Fungus Aspergillus terreusArticle Published on 2021-06-022022-10-30 Journal: Molecules [Category] COVID-19, MERS, SARS, [키워드] activities activity Analysis Anti-inflammatory antiallergic Aspergillus terreus butenolides candidate Chemical structure comparable Compound compounds COVID-19 COVID-19 Mpro COVID-19 pandemic COVID-19 vaccine derivatives drug drugs Effect Effectiveness Elastase experiments food fungus genomic sequencing in silico in vitro inflammatory complications inhibitory investigated lack M pro mutant NMR protease reported Research Secondary Metabolite tested treat variant were assessed WHO World Health Organization [DOI] 10.3390/molecules26113354 PMC 바로가기 [Article Type] Article
Development of an Animal Model of Onychomycosis in Guinea PigsArticle Published on 2020-12-312024-08-30 Journal: Nippon Ishinkin Gakkai Zasshi [Category] 백선증, [키워드] fungus Histopathology in vivo Nail Onychomycosis PMC 바로가기
Tinea corporis by Nannizia gypsea : delayed diagnosis due to unusual presentation ☆ ☆☆Nannizia gypsea에 의한 체부 백선: 비정상적인 증상으로 인한 지연된 진단 ☆ ☆☆Article Published on 2020-11-202024-07-28 Journal: Anais Brasileiros de Dermatologia [Category] 백선증, [키워드] Tinea corporis Antifungal Corticosteroids fungus [DOI] 10.1016/j.abd.2020.05.012 PMC 바로가기
Safety and efficacy assessment of allogeneic human dental pulp stem cells to treat patients with severe COVID-19: structured summary of a study protocol for a randomized controlled trial (Phase I / II)중증 COVID-19 환자를 치료하기 위한 동종 인간 치수 줄기세포의 안전성 및 효능 평가: 무작위 대조 시험(I/II상)을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2020-06-122022-08-13 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 Acidic Adenovirus Admission AIDS Alanine alanine aminotransferase albumin alkaline phosphatase Allogeneic allogeneic human dental pulp stem cells amyloid Analysis anion gap Arm ratio aspartate Aspartate aminotransferase average B lymphocyte basophils Before menopause Bilirubin blind blinded Block randomization method Blood blood cell Blood cells blood pressure Blood routine C-reactive protein calcium carbon dioxide Care CAST caused Cell cell suspension change chest X-ray Child Pugh score chlorine cholesterol cholinesterase CLARITY clinical Clinical improvement clinical trial coded Coefficient of variation color commenced comparator computer Concentration Consent consent form Continuous renal replacement therapy control group control groups COVID-19 COVID-19; randomised controlled trial; protocol; human dental pulp stem cells; dental stem cell banking COVID-2019 creatine creatine kinase creatinine criteria crystal Cytokines cytomegalovirus cytomegalovirus CMV-IgG cytomegalovirus CMV-IgM Definition dental pulp dental pulp stem cells description detect Diastolic blood pressure direct bilirubin discharge disease dissemination distress distribution DPSCs ECMO Efficacy element enrolled eosinophil eosinophils epithelial cells estimated glomerular filtration rate Estrogen examined excluded exclusion criteria experimental group fat globules Female patients female subject filtration rate Final flow cytometry follow-up period fungi fungus Globulin glomerular filtration rate Glucose GRADE Grade 1 grade 3 Grade 5 granulocyte HBcAb HBeAb HBeAg HBsAb HBsAg hDPSCs Health Organization heart rate hematocrit Hemodialysis hemoglobin hepatitis B hepatitis C HFNC high density lipoprotein hospitalised patient Hospitalised patients Hospitalization Hospitalized human DPSC human DPSCs hypersensitive C-reactive protein hypoxia Identifier IgA IgG IgM Il -10 IL-1 IL-1 β IL-2 IL-4 IL-6 immune Immunoglobulin Immunological testing improvement IMV inclusion criteria Infectious disease Influenza Influenza virus informed consent form injection Injections intensive care intensive care unit Intravenous injection Invasive mechanical ventilation investigator investigators ITN-γ ketone ketone bodies Kidney function Kidney function tests Killer cell Laboratory laboratory examinations Lactate lactate dehydrogenase lactating women leukocyte leukocyte enzymes lipoprotein lipoprotein A lipoprotein cholesterol low density lipoprotein lung lesion lung lesions lymphocyte Lymphocytes Macrophage Magnesium Medical care Menopause Monocytes mononuclear cell mononuclear cells nasal nasal catheter natural killer natural killer cell neutrophil Neutrophils nitrite NIV Non-invasive non-invasive mechanical ventilation non-squamous epithelial cell non-squamous epithelial cells nucleic acid nucleic acid test number objective observation occult occult blood Other Other condition outcome oxygen oxygen saturation parallel group parasites partial pressure participant Patient penetration performed Peripheral blood Peritoneal dialysis phase phenotype phosphatase phosphorus Placebo placebo-controlled Platelet Platelet count platelet distribution width Platelets Potassium prealbumin pregnancy test pregnant pressure Primary outcome Protein protocol random randomisation randomization Randomized Randomized controlled trial receive receiving recruitment red blood cell red blood cells renal renal insufficiency renal replacement therapy Renmin Hospital replacement therapy required researcher respiratory respiratory distress respiratory infection respiratory rate Safety Saline saline solution Sample size SARS-CoV-2 secondary Secondary outcomes serious COVID-19 serum serum amyloid severe liver condition severe pneumonia single-cell analyses sodium specific gravity Standard deviation status stem cell study period Study protocol sugar syphilis Systolic blood pressure T lymphocyte Th1 cytokine Th1 cytokines Th2 cytokine Th2 cytokines therapeutic effect therapeutic effects time TNF-a Total total bilirubin Total cholesterol total protein traits Transferrin treat Treatment treatment for COVID-19 triacylglycerol Trial triple blinded TTCI Tuberculosis Twenty participant Twenty participants university urea uric acid Urine urobilinogen Variation Version vital signs Volume website White blood cells with HIV within 6 months women World Health Organization Wuhan γ-glutamyl transferase [DOI] 10.1186/s13063-020-04380-5 PMC 바로가기 [Article Type] Letter
Emerging drugs for the treatment of onychomycosisArticle Published on 2019-12-312024-08-30 Journal: Expert Opin Emerg Drugs [Category] 백선증, [키워드] Antifungal Dermatophyte fungus itraconazole Onychomycosis terbinafine Tinea unguium PMC 바로가기
Selection of Candida albicans trisomy during oropharyngeal infection results in a commensal-like phenotype구강 인두 감염 동안 Candida albicans 삼염색체를 선택하면 공생 유사 표현형이 나타납니다.Research Article Published on 2019-05-152022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] acquisition Acute stress adhere Affect allelic Alter amplification analyzed antifungal agents Author benefit Candida Candida albican Candida albicans caused change Characteristics chromosome chromosomes clone clones commensal conserved de novo de novo mutation de novo mutations determine diploid elicited epithelial cell epithelial cells exhibited exposure to expression facilitate Frequency functional fungal fungal pathogen fungal pathogens fungus Genome growth Host host response in vitro in vivo Infection Inflammatory Interaction isolate killing less Lineage mice MOST mouse model much higher mutations neutrophil oral infections Oropharyngeal Pathogens phenotype Phenotypes Post-infection proliferate recognize reduced respond selected Selection significantly significantly lower strain Strains subsequent susceptibility These data tongue trisomy virulence weight loss while Whole genome sequencing [DOI] 10.1371/journal.pgen.1008137 PMC 바로가기 [Article Type] Research Article
Pheromone independent unisexual development in Cryptococcus neoformansCryptococcus neoformans의 페로몬 독립 성 발달Research Article Published on 2017-05-032022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] activator allele Analysis Bifurcation bisexual reproduction calcineurin cellular cellular differentiation Complete completion component condition conditions contributed Cryptococcus Cryptococcus neoforman Cryptococcus neoformans differentiation processe distribution dominant door ENhance eukaryotic expression favor fungus generate genetic control genetic study higher eukaryotes hyphal inactivation independent independent of inefficient inhibitory insertional mutagenesis isolate Laboratory Like mating type mating types meiosis microbe mode opens pathway pheromone Population predicted Prevalence progeny promote Protein repressor required robust sexual development sexual reproduction skewed skewed distribution specific proteins suppresse tested transcription factor Transcriptome undergo Znf2 [DOI] 10.1371/journal.pgen.1006772 PMC 바로가기 [Article Type] Research Article