genomic variant – Page 2 – Communicable Diseases Research

Insights into the evolutionary and prophylactic analysis of SARS-CoV-2: A review

Review

Published on 2021-11-242022-10-04
Journal: Journal of virological methods
[Category] COVID19(2023년), MERS, SARS, 변종, 치료제,

A common methodological phylogenomics framework for intra-patient heteroplasmies to infer SARS-CoV-2 sublineages and tumor clones

SARS-COV-2 Sublineages 및 종양 클론을 추론하는 환자 내 이종성을위한 일반적인 방법 론적 계통 발생 유전학 프레임 워크

Research

Published on 2021-11-162022-09-10
Journal: BMC Genomics
[Category] MERS, SARS, 변종, 유전자 메커니즘,

[키워드] Accuracy acquisition assumption Birth Cancer cancer patient capture clinically Clonal evolution clone clones co-infecting COVID-19 COVID-19 patient disease Evolution Frequency Genetic genetic material genomic genomic data genomic read genomic variant handle heterogeneity highlighting identify illness implication in viral Infection information methodological Mutation offer Phylogenetic Phylogenetic tree phylogenies Phylogenomics Phylogeny provide resistance mechanism resistance mechanisms Result SARS-CoV-2 SARS-CoV-2 virus supplementary material targets the mean the SARS-CoV-2 virus therapeutic therapy Treatment Tumor Tumor evolution undergo variant frequency Viral
[DOI] 10.1186/s12864-021-07660-9 PMC 바로가기 [Article Type] Research

Assessing Multiplex Tiling PCR Sequencing Approaches for Detecting Genomic Variants of SARS-CoV-2 in Municipal Wastewater

Observation

Published on 2021-10-192022-10-29
Journal: mSystems
[Category] COVID-19,

[키워드] acute respiratory syndrome Amplicon amplicons approach approach Assessing breadth Canada Characteristics circulating collected complement coronavirus coronavirus disease correlated correlation Coverage COVID-19 COVID-19 outbreak effort epidemiological Epidemiology FIVE genome coverage Genome sequencing genomic genomic variant greater Guidance median monitoring multiplex Mutation offer outbreak Patient PCR plant primer provided resulting RNA RNA degradation SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 RNA Sequencing significantly significantly higher Support Surveillance the SARS-CoV-2 virus Treatment variants virus wastewater whole-genome sequencing
[DOI] 10.1128/mSystems.01068-21 PMC 바로가기 [Article Type] Observation

Implementation of serological and molecular tools to inform COVID-19 patient management: protocol for the GENCOV prospective cohort study

COVID-19 환자 관리를 알리는 혈청학적 및 분자적 도구의 구현: GENCOV 전향적 코호트 연구를 위한 프로토콜

Article

Published on 2021-09-302022-09-11
Journal: BMJ Open
[Category] SARS, 변종, 진단,

[키워드] Adult patients antibody Antibody Response antibody titres Antigen approved association B-cell baseline blood sample Blood samples Characteristics clinical Clinical data clinical trials Clinical Trials Ontario collected conducted correlated COVID-19 COVID-19 patient COVID-19 symptoms determine Diagnosis diagnostics disease severity Ethics evaluate genetic difference genetic differences genetic marker Genetic markers genetics Genome Genome sequencing genomic variant Greater Toronto Area hospitals Host host genome identify immune response immunology Infection information isotype leucocyte Lineage molecular molecular diagnostics molecular diagnostics. Observational cohort study outcome outcomes participant Patient patients with COVID-19 peer-reviewed physiological response prospective cohort study protocol receiving receptor Regression regression models Research Research Ethics review SARS-COV-2 infection SARS-CoV-2 virus sequence information sequenced Sequencing serological severity severity of COVID-19 Symptom System T-cell the antibody response the SARS-CoV-2 virus Variability Viral viral genomes viral neutralisation virus genome
[DOI] 10.1136/bmjopen-2021-052842 PMC 바로가기 [Article Type] Article

RT-PCR based SARS-CoV-2 variant screening assays require careful quality control

RT-PCR 기반 SARS-CoV-2 변이체 스크리닝 분석에는 신중한 품질 관리가 필요합니다.

Article

Published on 2021-08-012022-09-11
Journal: Journal of Clinical Virology
[Category] SARS, 변종, 치료기술, 치료제,

[키워드] Accuracy antibody asked bioinformatic analysis characteristic complex confidence copy number detect determine diagnostic external quality assessment FIVE genetic information Genetic variations genomic variant genomic variants Genotype highest identify initial Interpretation Laboratory less lineages loss of confidence melting melting curve analysis molecular nucleotide nucleotide mutation nucleotide mutations participant pathogenicity qPCR Quality control reliability reported RT-PCR RT-qPCR SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 variant Sequencing Spike protein target region target regions the SARS-CoV-2 time-consuming Transmission variant Variant of concern. variants of concern Variation virus VoC whole genome Whole genome sequencing
[DOI] 10.1016/j.jcv.2021.104905 PMC 바로가기 [Article Type] Article

Variant Analysis of SARS-CoV-2 Genomes from Belgian Military Personnel Engaged in Overseas Missions and Operations

해외 임무 및 운영에 종사하는 벨기에 군인의 SARS-COV-2 게놈의 변형 분석

Article

Published on 2021-07-132022-09-10
Journal: Viruses
[Category] SARS, 변종, 유전자 메커니즘,

[키워드] 2019 coronavirus disease acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Afghanistan Armed Forces B.1 B.1.525 causative agent China clade Contact tracing containment strategies coronavirus coronavirus disease COVID-19 decrease Democratic Republic disease severity Efficacy force Genomic epidemiology genomic variant genomic variants Genotype increase in influx Isolation Lineage lineages military Nextstrain Niger operation outbreak Phylogenetic analysis populations raise regions respiratory risk RT-qPCR SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants screened severe acute respiratory syndrome Coronavirus Soldiers specific mutation specific mutations Spread Transmissibility Transmission Travel Vaccine vaccine efficacy variant variants Viral viral lineages virus
[DOI] 10.3390/v13071359 PMC 바로가기 [Article Type] Article

Permethrin resistance in Aedes aegypti : Genomic variants that confer knockdown resistance, recovery, and death

Aedes Aegypti의 퍼메 트린 저항 : 녹다운 저항, 회복 및 사망을 부여하는 게놈 변이체

Research Article

Published on 2021-06-172022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] Aede Amino acid amino acid substitution amino acid substitutions association calcium calcium channel Chikungunya comparison Concentration cuticle dead death Dengue dependent on detoxification detoxification enzymes develop directional disease disease control disease outbreaks effective Frequency functional Genes genetic background Genome genomic genomic variant genomic variants heterogeneous population identify IMPROVE individual information insecticide insecticides knockdown knockdown resistance lead list marker mechanism metabolism moderate Mosquito Mutation occur Outbreaks penetration performed Permethrin phenotype phenotypic polymorphism Population populations Prevent proportion protein coding genes Proteins provide public health pyrethroid Pyrethroids reduce Region resistance mechanism resistance mechanisms response sequenced single-nucleotide Single-nucleotide polymorphisms SNPs sodium sodium channel suppress suppression survival tested transmitted Treatment Vaccine variant vector control viral disease Viral diseases voltage voltage-gated sodium channel Zika Zika viruses
[DOI] 10.1371/journal.pgen.1009606 PMC 바로가기 [Article Type] Research Article

Population Dynamics and Structural Effects at Short and Long Range Support the Hypothesis of the Selective Advantage of the G614 SARS-CoV-2 Spike Variant

G614 SARS-CoV-2 스파이크 변형의 선택적 이점에 대한 가설을 뒷받침하는 근거리 및 장거리 인구 역학 및 구조적 효과

Article

Published on 2021-05-042022-09-11
Journal: Molecular Biology and Evolution
[Category] SARS, 변종,

[키워드] affecting clinical samples coalescent-based inference conformational connection country domain drugs Dynamics Effect Epidemics explain explained Frequency functional furin G614 variant generalized linear mixed models genomic variant genomic variants Hypothesis increase infections information invasive linear Long Modification modify molecular molecular dynamics molecular dynamics simulations plasticity Population Population dynamics population dynamics. propagule proteolytic Range reached Receptor-binding domain S1/S2 SARS-CoV-2 SARS-CoV-2 evolution selective spike Spike protein Spread statistical analyses Support the receptor-binding domain the spike protein Transmission variant virus
[DOI] 10.1093/molbev/msaa337 PMC 바로가기 [Article Type] Article

In response to: Multiple assays in a real-time RT-PCR severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) panel can mitigate the risk of loss of sensitivity by new genomic variants during the COVID-19 outbreak

이에 대한 대응: 실시간 RT-PCR 중증 급성 호흡기 증후군 코로나바이러스-2(SARS-CoV-2) 패널의 다중 분석은 COVID-19 발병 기간 동안 새로운 게놈 변이체에 의한 감수성 손실 위험을 완화할 수 있습니다

Comment

Published on 2021-04-012022-09-11
Journal: International Journal of Infectious Diseases
[Category] SARS, 변종, 유전자 메커니즘,

[키워드] acute respiratory syndrome Coronavirus-2 COVID-19 outbreak genomic variant mitigate Multiple real-time RT-PCR risk SARS-CoV-2 sensitivity
[DOI] 10.1016/j.ijid.2021.01.049 PMC 바로가기 [Article Type] Comment

Genomic and healthcare dynamics of nosocomial SARS-CoV-2 transmission

병원 내 SARS-CoV-2 전염의 게놈 및 의료 역학

Research Article

Published on 2021-03-172022-09-10
Journal: eLife
[Category] SARS, 변종,