global public health emergency – Page 2 – Communicable Diseases Research

Coronavirus disease 2019 and first-trimester spontaneous abortion: a case-control study of 225 pregnant patients

2019년 코로나바이러스 질병 및 임신 초기 자연유산: 225명의 임산부를 대상으로 한 사례 대조 연구

Article

Published on 2021-04-012022-09-11
Journal: American journal of obstetrics and gynecology [Category] MERS, SARS, 진단, 치료기술,

Management of SARS-CoV-2 pneumonia

SARS-CoV-2 폐렴 관리

Review

Published on 2021-03-012022-09-11
Journal: Journal of medical virology [Category] Fulltext, MERS, 유전자 메커니즘, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus age airway airways cells Characteristics clinical conditions Clinical course clinical presentation consequence coronavirus disease Coronavirus-2 correlated COVID-19 death distribution elevated evaluate Factor General health genetics global public health global public health emergency Health Hospitalization hospitalizations Host Immune status Infection intensive care units knowledge lung Lungs management mechanism Mild Pneumonia receptor SARS-CoV-2 SARS-CoV-2 disease SARS-COV-2 infection SARS-CoV-2 pneumonia severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 severity Spread Viral load virus
[DOI] 10.1002/jmv.26470 PMC 바로가기 [Article Type] Review

Factors Influencing Viral Clearance in Mild COVID-19 and Clinical Characteristics of Asymptomatic Patients

경증 COVID-19에서 바이러스 제거에 영향을 미치는 요인 및 무증상 환자의 임상 특성

Clinical Trial

Published on 2021-02-262022-09-10
Journal: BioMed Research International [Category] 임상, 치료기술,

[키워드] 95% CI Admission age analyzed Asymptomatic asymptomatic patient Beta caused Characteristics clearance clinical clinical feature Clinical features clinical symptom collected Comorbidities Comorbidity Computed tomography coronavirus coronavirus disease COVID-19 COVID-19 pandemic Delayed discharged patient discharged patients evaluate evaluated Factor global public health global public health emergency identify illness onset infected with SARS-CoV-2 interquartile range involved IQR laboratory-confirmed male median age median time Mortality Multiple linear regression no significant differences objective outbreak outcome Patient patients with COVID-19 Pneumonia predict predictor reduce Registered registration number Result SARS-CoV-2 SARS-CoV-2 infections SARS-CoV-2 RNA SARS-CoV-2 RNA detection significant difference Spread symptomatic patient the median Trial Trial Registration Number Viral viral clearance viral persistence virus
[DOI] 10.1155/2021/5909612 PMC 바로가기 [Article Type] Clinical Trial

SARS-CoV-2 genomic characterization and clinical manifestation of the COVID-19 outbreak in Uruguay

우루과이에서 발생한 COVID-19 발병의 SARS-CoV-2 게놈 특성 및 임상 징후

Coronaviruses

Published on 2021-01-152022-09-10
Journal: Emerging Microbes & Infections [Category] SARS, 변종, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis Arterial hypertension association caused clade clinical correlations clinical parameter Cohort contribute coronavirus correlated correlation COVID-19 COVID-19 outbreak D614G D614G mutation disease dominance FIVE full genome amplicon sequencing Genetic genomic global public health global public health emergency Health Organization Healthcare system hypertension ICU admission independent Inpatients kidney Kidney failure Latin America Local make up minimum Mutation non-structural protein outbreak outcome outpatients and inpatient pandemic partial lockdown performed phylodynamic phylogeographic analysis phylogeographic BEAST analysis respiratory Respiratory illness resulting SARS-CoV-2 SARS-COV-2 infection sequence sequenced sequences severe acute respiratory syndrome Coronavirus significantly South South America spike D614G genetic mutation the SARS-CoV-2 Transmission transmission clusters transmissions Uruguay Viral viral genome viral genomes viral strain viral strains virus World Health Organization
[DOI] 10.1080/22221751.2020.1863747 PMC 바로가기 [Article Type] Coronaviruses

Whole Genome Identification of Potential G-Quadruplexes and Analysis of the G-Quadruplex Binding Domain for SARS-CoV-2

잠재적인 G-사중체의 전체 게놈 식별 및 SARS-CoV-2에 대한 G-사중체 결합 도메인 분석

Genetics

Published on 2020-11-272022-08-13
Journal: Frontiers in Genetics [Category] 유전자 메커니즘,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Amino acid amino acid residue amino acid residues amino acid sequence Analysis Antiviral betacoronaviruses binding affinity caused characterized conserved coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 dimer domain Drug discovery electrostatic exhibited feature G-quadruplex G-quadruplex binding domain G4 global public health global public health emergency human transcriptome humans identification in some infect other coronavirus pandemic positive Potential Research respiratory retained SARS-CoV-2 secondary structures selective sequence severe acute respiratory syndrome Coronavirus shown SUD-homology structure target targets the binding affinity the SARS-CoV-2 Transcriptome Viral
[DOI] 10.3389/fgene.2020.587829 PMC 바로가기 [Article Type] Genetics

No benefit of hydroxychloroquine in COVID-19: Results of Systematic Review and Meta-Analysis of Randomized Controlled Trials”

COVID-19에서 하이드록시클로로퀸의 이점 없음: 무작위 대조 시험의 체계적인 검토 및 메타 분석 결과"

Meta-Analysis

Published on 2020-11-012022-09-11
Journal: Diabetes & metabolic syndrome [Category] SARS, 임상,

[키워드] affected Analysis antiviral medication article benefit Chloroquine clinical Clinical outcome clinical trials Compound conducted control group Controlled coronavirus COVID-19 COVID-19 disease COVID-19 patient COVID-19 patients disease Efficacy Evidence global public health global public health emergency HCQ Hydroxychloroquine hydroxychloroquine group indicated management medRxiv Meta-analysis Mild mild to moderate mild to moderate COVID-19 disease Moderate COVID-19 Mortality not significant Odds ratio outcome pandemic Patient patients patients treated reported Result review risk risk difference SARS-COV-2 infection Standard of care statistically study population systematic review treated Treatment treatment guidelines Trial was done
[DOI] 10.1016/j.dsx.2020.08.033 PMC 바로가기 [Article Type] Meta-Analysis

Mitigation of the replication of SARS-CoV-2 by nitric oxide in vitro

시험관 내 산화질소에 의한 SARS-CoV-2 복제 완화

Article

Published on 2020-10-012022-09-11
Journal: Redox Biology [Category] SARS, 치료제,

[키워드] 3CL 3CL Protease active site acute respiratory syndrome Antiviral effect Care cells correlated CoV replication COVID-19 cysteine dose effective effort enzyme evaluated expected FRET global public health global public health emergency Health Health care health care systems hypoxia in vitro inhibit SARS-CoV-2 inhibitory effect Mitigation nitric oxide Patient prevented Prophylaxis protease protective effect reducing reduction in released Replication replication of SARS-CoV-2 respiratory S-nitroso-N-acetylpenicillamine SARS-CoV SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pandemic SARS-CoV-2 protease SARS-CoV-2 replication Severe acute respiratory syndrome SNAP tested treated Treatment Vaccine Viral viral cytopathic effect viral replication
[DOI] 10.1016/j.redox.2020.101734 PMC 바로가기 [Article Type] Article