Glucose-6-Phosphate Dehydrogenase Deficiency: An Actionable Risk Factor for Patients with COVID-19?Research article Published on 2020-10-012022-10-05 Journal: Archives of medical research [Category] SARS, 변종, [키워드] affected African Asian Asymptomatic coronavirus COVID-19 COVID-19 infection deficiency dehydrogenase drug drugs element Factor G6PD Genetic glucose-6-phosphate dehydrogenase Glucose-6-phosphate deydrogenase deficiency hemolytic anemia individual individuals Infection Latin Mutation outcome oxidative stress Patient populations prevalent risk factor treat viral infection X-linked [DOI] 10.1016/j.arcmed.2020.06.006 [Article Type] Research article
Methemoglobinemia in Patient with G6PD Deficiency and SARS-CoV-2 InfectionResearch Letter Published on 2020-09-012022-10-31 Journal: Emerging Infectious Diseases [Category] COVID-19, SARS, [키워드] acute respiratory syndrome coronavirus coronavirus disease COVID-19 deficiency G6PD Glucose-6-phosphate glucose-6-phosphate dehydrogenase Hemolysis hemolytic anemia Infection methemoglobinemia Patient potential risk precipitated pulse oximetry respiratory infections SARS CoV-2 SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 viruses zoonoses [DOI] 10.3201/eid2609.202353 PMC 바로가기 [Article Type] Research Letter
Addressing the gender-knowledge gap in glucose-6-phosphate dehydrogenase deficiency: challenges and opportunities포도당-6-인산 탈수소효소 결핍에서 성별-지식 격차 해소: 도전과 기회Review Published on 2019-01-032024-08-26 Journal: International Health [Category] 말라리아, [키워드] chromosome Gender glucose-6-phosphate dehydrogenase point-of-care X-inactivation [DOI] 10.1093/inthealth/ihy060 PMC 바로가기 [Article Type] Review
Machine learning prioritizes synthesis of primaquine ureidoamides with high antimalarial activity and attenuated cytotoxicityarticle Published on 2018-02-282024-09-01 Journal: European Journal of Medicinal Chemistry [Category] 말라리아, [키워드] Antimalarial activity glucose-6-phosphate dehydrogenase Plasmodium falciparum primaquine QSAR Ureidoamide [Article Type] article
G6PD deficiency alleles in a malaria-endemic region in the Western Brazilian Amazon말라리아 유행 지역인 서부 브라질 아마존의 G6PD 결핍 대립유전자Research Published on 2017-06-152024-08-12 Journal: Malaria Journal [Category] 말라리아, [키워드] genetic variants glucose-6-phosphate dehydrogenase malaria [DOI] 10.1186/s12936-017-1889-6 PMC 바로가기 [Article Type] Research
Safety of a single low-dose of primaquine in addition to standard artemether-lumefantrine regimen for treatment of acute uncomplicated Plasmodium falciparum malaria in Tanzania탄자니아에서 급성 비복합 플라스모디움 팔시파룸 말라리아 치료를 위한 표준 아르테메터-루메판트린 요법에 단일 저용량 프리마퀸을 추가한 안전성Research Published on 2016-06-102024-08-12 Journal: Malaria Journal [Category] 말라리아, [키워드] Anaemia glucose-6-phosphate dehydrogenase Plasmodium falciparum malaria primaquine [DOI] 10.1186/s12936-016-1341-3 PMC 바로가기 [Article Type] Research
Diminished COX-2/PGE 2 -Mediated Antiviral Response Due to Impaired NOX/MAPK Signaling in G6PD-Knockdown Lung Epithelial CellsResearch Article Published on 2016-04-202022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] A549 cell A549 cells addition Affect antiviral activity antiviral response Cell cellular chloride coronavirus 229E decrease decreased expression deficiency diminished downstream DPI dysregulated expression G6PD glucose-6-phosphate dehydrogenase homeostasis Impaired Infection Inflammatory response inhibitor MAPK NADPH NADPH oxidase NF-κB occurred oxidative stress PGE Phosphorylation provide reduced reducing Regulation response Signaling subunit susceptibility These data TNF-α transcriptional level Treatment tumor necrosis factor-α up-regulated viral infections viral replication was determined [DOI] 10.1371/journal.pone.0153462 PMC 바로가기 [Article Type] Research Article
Glucose-6-Phosphate Dehydrogenase Enhances Antiviral Response through Downregulation of NADPH Sensor HSCARG and Upregulation of NF-κB SignalingArticle Published on 2015-12-172022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] activity Alpha Analysis Antiviral antiviral response Cell cells coronavirus Degradation dehydrogenase DNA binding downregulated enterovirus examined Exogenous expression G6PD glucose-6-phosphate dehydrogenase GTPase HCoV-229E HSCARG human coronavirus 229E IDH1 increased expression Infection inhibited IκB mechanism MX1 NADPH Necrosis NF-κB NF-κB signaling nicotinamide adenine dinucleotide overexpression phosphate promoter Protein reduced response resulting sensor siRNA suppressed susceptibility susceptible TNF- α upregulated viral gene expression viral infection virus infection [DOI] 10.3390/v7122966 PMC 바로가기 [Article Type] Article
Malaria proteomics: insights into the parasite-host interactions in the pathogenic spacearticle Published on 2014-01-312024-09-01 Journal: Journal of Proteomics [Category] 말라리아, [키워드] 2-D Fluorescence Difference Gel Electrophoresis 2D-DIGE 2D-nanoflow high-performance liquid chromatography 2D-nanoLC 2D-PAGE 4-HNE 4-hydroxy-2-nonenal Apical sushi protein ASP G6PD GBA glucose-6-phosphate dehydrogenase glycosylphosphatidylinositol GPF GPI Green-fluorescent protein Guilt by association heat shock protein Heat shock protein-70 HSP Hsp70 immunomics infected red blood cells iRBCs malaria Merozoite surface protein MSP MudPIT Multidimensional protein identification Pathogenic space PKA Plasmepsin Plasmepsin II PM PM-II post-translational modifications protein kinase A proteomics PTMs ramA RBC reactive oxygen species red blood cell Rhoptry-associated membrane antigen ROS sera Serine repeat antigen Subproteome two-dimensional gel electrophoresis [Article Type] article