Unravelling the Phytochemical Composition and the Pharmacological Properties of an Optimized Extract from the Fruit from Prunus mahaleb L.: From Traditional Liqueur Market to the Pharmacy ShelfArticle Published on 2021-07-222022-10-30 Journal: Molecules [Category] Coronavirus, SARS, [키워드] Prunus mahaleb L. ACE2 anti-bacterial effects anti-COVID-19 effects antimicrobial Bacterial blunting cells chicoric acid clinical symptom Colon downregulation Effect Effects Extract fruit Gene Expression gram H1299 human host in vitro indicate inhibit SARS-CoV-2 investigated Liqueur Local lung adenocarcinoma neuroprotection Pharmacy phenolic profile phytochemical property Protective effects Prunus mahaleb reducing scavenging shelf Strains Support tested TMPRSS2 TNFα Traditional Treatment ulcerative colitis VEGFA virus entry was measured [DOI] 10.3390/molecules26154422 PMC 바로가기 [Article Type] Article
Bacterial but no SARS-CoV-2 contamination after terminal disinfection of tertiary care intensive care units treating COVID-19 patientsCOVID-19 환자를 치료하는 3차 치료 중환자실의 최종 소독 후 박테리아는 있지만 SARS-CoV-2 오염 없음Research Published on 2021-01-122022-09-10 Journal: Antimicrobial Resistance and Infection Control [Category] 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus 2 aerosol Bacteria Bacterial Care Contamination coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 defined Disinfection Enterococcus faecium gram high risk Hospital epidemiology Hydrogen peroxide nebulisation ICU ICUs intensive care unit intensive care units invasive ventilation measure Non-COVID-19 patients nosocomial Nosocomial infection Nosocomial transmission Patient preparation respiratory Result Ribonucleic acid RNA SARS-CoV-2 SARS-CoV-2 RNA Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 skin surface Swab swabs Transmission treat treating COVID-19 patient [DOI] 10.1186/s13756-021-00885-z PMC 바로가기 [Article Type] Research
Phage infection and sub-lethal antibiotic exposure mediate Enterococcus faecalis type VII secretion system dependent inhibition of bystander bacteria파지 감염 및 준치사 항생제 노출은 Enterococcus faecalis type VII 분비 시스템 의존적 방관자 억제 억제를 매개합니다.Research Article Published on 2021-01-072022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] abrogate activated addition Affect antagonism antibacterial activity antibiotic Antibiotics Bacteria Bacterial bacterial cell bacterial cells Bacterial infections bacterial pathogen bacteriophage bacteriophages bacterium bystander Cell cells clinically Concentration Consensus consequence Contact Deletion Disruption DNA damage DNA damaging dose Enterococcus Evidence evidence of expression facilitate Gene Expression gram growth highlight Host Immunity independent independent of induce Infection Interaction intrinsic killing membrane microbial Microbial communities multi-drug resistant multidrug resistant pathogen phage phages positive predicted respond restrict resulting secretion Serine Staphylococcus aureus Stress stress response Stressor susceptible therapeutic therapy These data threonine Transcription transcription factor Treatment Trigger triggering triggers upstream [DOI] 10.1371/journal.pgen.1009204 PMC 바로가기 [Article Type] Research Article
SweC and SweD are essential co-factors of the FtsEX-CwlO cell wall hydrolase complex in Bacillus subtilisSweC와 SweD는 Bacillus subtilis에서 FtsEX-CwlO 세포벽 가수분해효소 복합체의 필수 보조인자입니다.Research Article Published on 2019-08-222022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] ABC Amino acid amino acid substitution amino acid substitutions ATPase Author autolytic enzymes Bacillus subtilis Bacteria bacterial cell bacterial species Cell cell division cell wall characterized cleavage complex composed conserved Control control cell cytokinesis division divisome domain enzyme Factor firmicutes function gram gram-positive bacterium growth homologs hydrolase Hydrolases involved mechanism membrane osmotic lysis peptide peptides peptidoglycan performed Prevent PROTECT Protective Protein regulate regulated Regulatory remodeling required residue residues sacculus subset Support synthesis the cell [DOI] 10.1371/journal.pgen.1008296 PMC 바로가기 [Article Type] Research Article
Epistatic control of intrinsic resistance by virulence genes in Listeria리스테리아의 병독성 유전자에 의한 내인성 내성의 상위성 조절Research Article Published on 2018-09-042022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] activated Activation addition antibiotic antimicrobial resistance antimicrobial susceptibility Bacteria Bacterial bacterial cell complex conditions core genome determinant dissect drug drug-resistant Effect enzyme epistasis Evidence Evolution evolutionary dynamics fosfomycin functional Genes genomic gram gram-positive bacterium Host in vitro induce Infection Infectious disease Interaction intrinsic intrinsically isolate L . monocytogene Listeria Listeria monocytogene Listeria monocytogenes listeriosis loci locus mechanism microbe molecular molecular basis organism pathogen pathogenic Pathogens phenomenon phenotype phenotypic effect Population dynamics prfA PROTECT provide rationale reported resistance gene resistance genes Strains suppressed susceptibility susceptible traits treat Treatment understanding virulence virulence gene virulence genes virulent working [DOI] 10.1371/journal.pgen.1007525 PMC 바로가기 [Article Type] Research Article
Systems Level Analyses Reveal Multiple Regulatory Activities of CodY Controlling Metabolism, Motility and Virulence in Listeria monocytogenes시스템 수준 분석을 통해 Listeria monocytogenes에서 대사, 운동성 및 독성을 제어하는 CodY의 여러 조절 활동이 밝혀졌습니다.Research Article Published on 2016-02-192022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] actA activate activator activity adaptation Affect Amino acid amino acids Analysis Bacteria bacterial pathogen Bacterial pathogens BCAA bind binding branch CodY condition conditions controlling dependent on DNA DNA binding environmental cues expression facilitate function functions Gene Expression Genes Genome gram Gram-positive bacteria growth Host identify identifying L . monocytogene Level Ligand ligands Listeria Listeria monocytogene Listeria monocytogenes mammalian metabolic genes metabolism modulate motility Multiple multiple pathway multiple pathways observation pathogen Pathogens pathway Pathways performed previous study prfA raised regulated regulator gene Regulatory regulatory network reported repress repressor respond response responses Sequencing Stress stress responses System Target genes thought traits Transcription transcription factor transcription factors virulence virulence gene virulence genes [DOI] 10.1371/journal.pgen.1005870 PMC 바로가기 [Article Type] Research Article
Global Analysis of the Sporulation Pathway of Clostridium difficileClostridium difficile의 포자 형성 경로에 대한 글로벌 분석Research Article Published on 2013-08-082022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] activated activating Activation Analysis Antibiotics Author B. subtilis Bacillus subtilis Clostridia Clostridium Clostridium difficile Colitis Complication determine determined diagnostic biomarker Diagnostic biomarkers diarrhea expression Factor firmicutes framework function Gene gene product Genes genes encoding gram highlight identify Infection infectious infectious diarrhea lead life-threatening loss-of-function mutation loss-of-function mutations mechanism mutant organism pathogen Pathogenesis performed predicted provide pseudomembranous colitis question recurrence regulate regulated Regulatory regulatory pathway related required responsible Sequencing sigma spore spores sporulation Spread the United State Transcription transcriptional Transmission treat United States whole-genome [DOI] 10.1371/journal.pgen.1003660 PMC 바로가기 [Article Type] Research Article
RpoS Plays a Central Role in the SOS Induction by Sub-Lethal Aminoglycoside Concentrations in Vibrio choleraeRpoS는 Vibrio cholerae에서 치명적이지 않은 아미노글리코사이드 농도에 의한 SOS 유도에서 중심 역할을 합니다Research Article Published on 2013-04-112022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] addressed Aminoglycoside Antibiotic resistance Antibiotics Author Bacteria Bacterial caused cellular mechanism cellular mechanisms CENTRAL Concentration connection conserved corollary different DNA DNA damage DNA damaging E. coli Escherichia coli flow cytometry found Frequency fusion gene transfer Genetic Genome genomic plasticity gram growth guanine horizontal gene Horizontal gene transfer increase in induce induction inhibit inhibitory concentration Klebsiella pneumoniae leads low dose Mutation mutations Other over-expression oxidative oxidative stress oxidative stress response oxidized oxygen paradigm pathogen Pathogens pathway Pathways physiological effect physiological effects physiological response pneumoniae Prevent promoter Protein reactive oxygen specy regulated related role RpoS shown SOS SOS response Stress stress conditions stress response Testing tobramycin transfer V. cholerae Vibrio cholerae [DOI] 10.1371/journal.pgen.1003421 PMC 바로가기 [Article Type] Research Article