Harmonization and standardization of data for a pan-European cohort on SARS- CoV-2 pandemic Research Published on 2022-06-142022-10-05 Journal: NPJ Digital Medicine [Category] 유전자 메커니즘, 진단, [키워드] addition Analysis Cluster Cohort collected contributed COVID-19 development Effect element Establishing European facilitate harmonization heterogeneous information knowledge pandemic Prospective Study retrospective SARS- CoV-2 Standard Standardization terminology Treatment variable [DOI] 10.1038/s41746-022-00620-x [Article Type] Research
Nationwide Harmonization Effort for Semi-Quantitative Reporting of SARS-CoV-2 PCR Test Results in Belgium벨기에 SARS-CoV-2 PCR 검사 결과 반정량적 보고를 위한 전국적인 조화 노력Article Published on 2022-06-142022-09-12 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] absence affected Asymptomatic Belgium calculated category clinician Concentration Contact tracing Course cycle threshold database determine driven by effort Factors harmonization indications Infection Infectivity information Laboratory Leuven National National Reference Centre pandemic PCR PCR assay positive PCR result Reporting Result resulting RNA RNA copies/mL SARS-CoV-2 SARS-CoV-2 PCR SARS-CoV-2 test semi-quantitative semi-quantitative PCR semi-quantitative reporting. serological standard curve Standard deviation target gene Test the mean threshold to define viral shedding [DOI] 10.3390/v14061294 PMC 바로가기 [Article Type] Article
Favipiravir (SARS-CoV-2) degradation impurities: Identification and route of degradation mechanism in the finished solid dosage form using LC/LC-MS methodFavipiravir(SARS-CoV-2) 분해 불순물: LC/LC-MS 방법을 사용하여 완성된 고체 제형의 분해 메커니즘 식별 및 경로Article Published on 2022-06-012022-09-11 Journal: Biomedical chromatography : BMC [Category] COVID19(2023년), SARS, 치료기술, [키워드] acetonitrile Analysis analyte approved buffer column temperature Compound concentrations condition country Degradation degradation impurities, favipiravir, LC/LC-MS, related substances, SARS-CoV-2, stability indicating. dosage Emergency use Favipiravir flow rate Forced harmonization HPLC identification injection International Conference LC-MS limit linear linearity mechanism Mobile molecular pathway performed physical Precision Quality control quantification reaction recovery study Research research and development robust SARS-CoV-2 SARS-CoV-2 patients separation stability Standard deviation stationary stationary phase stress conditions supported tablets temperature treat Volume water [DOI] 10.1002/bmc.5363 PMC 바로가기 [Article Type] Article
Quantitative analysis of favipiravir and hydroxychloroquine as FDA-approved drugs for treatment of COVID-19 using synchronous spectrofluorimetry: application to pharmaceutical formulations and biological fluids동시 분광형광법을 사용한 COVID-19 치료를 위한 FDA 승인 약물인 favipiravir 및 hydroxychloroquine의 정량 분석: 제약 제제 및 생물학적 유체에 적용Article Published on 2022-06-012022-09-11 Journal: Luminescence : the journal of biological and chemi [Category] COVID19(2023년), SARS, 치료기술, [키워드] Acetate acute respiratory syndrome Analysis applied approach biological fluid biological fluids buffer cause caused condition contagious coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 country COVID-19 Detection limit diluent drug Drug administration Ethanol exhibited Favipiravir FDA-approved drug fluorescence intensity food harmonization Healthcare systems human plasma sample human plasma samples Hydroxychloroquine identify information Interference International Conference investigated limit limits medications Pharmaceutical Preparation pharmaceutical preparations quantitation SARS-CoV-2 sensitivity Severe acute respiratory syndrome synchronous synchronous fluorimetry. Treatment United State United States United States Food and Drug Administration viral infection were measured [DOI] 10.1002/bio.4240 PMC 바로가기 [Article Type] Article
Use of hyphenated analytical techniques to identify the bioactive constituents of Gunnera perpensa L., a South African medicinal plant, which potently inhibit SARS-CoV-2 spike glycoprotein-host ACE2 bindingSARS-CoV-2 스파이크 당단백질-숙주 ACE2 결합을 강력하게 억제하는 남아프리카 공화국의 약용 식물인 Gunnera perpensa L.의 생리 활성 성분을 식별하기 위한 하이픈 연결 분석 기술의 사용Article Published on 2022-05-012022-09-11 Journal: Analytical and bioanalytical chemistry [Category] COVID19(2023년), SARS, 치료제, [키워드] ACE2 ACE2 binding African angiotensin Angiotensin-converting enzyme Antiviral antivirals binding causative agent cellular entry Compound Concentration COVID-19 described disrupt domain glycoprotein Gunnera Gunnera perpensa harmonization highlight Host hypothesised identify inhibit inhibit SARS-CoV-2 Interaction International Conference lack management morbidity and mortality neutralising antibody plant Protein Punicalagin Punicalin RBD RBD-ACE2 receptor Region REGN10987 SARS-CoV-2 SARS-COV-2 infection small molecule Small molecules South spike glycoprotein Spread UPLC UPLC-IMS-HRMS. Vaccines viral spike [DOI] 10.1007/s00216-022-04041-3 PMC 바로가기 [Article Type] Article
Pharmacopoeia roles and responses: A systemic resilience approach to COVID-19 pandemicCorrespondence Published on 2022-05-012022-10-05 Journal: Saudi Pharmaceutical Journal : SPJ [Category] 신약개발, [키워드] approach Corona virus COVID-19 COVID-19 crisis COVID-19 pandemic drugs effort evaluate globe Government harmonization Health Healthcare system measure Medicine Medicines Monographs pandemic Pharmacopoeia provide Reference standards Regulatory Authorities regulatory authority Resilience response resulting Treatment triangular Vaccine [DOI] 10.1016/j.jsps.2022.02.009 [Article Type] Correspondence
Comparative Greenness Metric Estimates for Content Uniformity Testing of Anti-Cov-2, GS-5734 in Commercial Vials: Validated Micellar Electrokinetic Chromatographic Assay상업용 바이알에서 Anti-Cov-2, GS-5734의 함량 균일성 테스트에 대한 비교 녹색도 측정법 추정: 검증된 미셀 동전기 크로마토그래피 분석Article Published on 2022-04-272022-09-11 Journal: Journal of AOAC International [Category] 치료기술, 치료제, [키워드] Analysis Antiviral antiviral drug antiviral properties antiviral property applied approved borate borate buffer can be used clinical trials Community Comparative content coronavirus correlation coefficient COVID-19 drug Drug administration Ebola Ebola virus effective estimate food green GS-5734 harmonization International Conference linear metric pandemic pharmaceutical industry phosphoramidate positive Remdesivir selectivity sensitivity silica sodium sodium dodecyl sulfate solvent sulfate Testing treat Treatment U.S. Food and Drug Administration uniformity urge viruses was used widespread [DOI] 10.1093/jaoacint/qsac001 PMC 바로가기 [Article Type] Article
Meeting the COVID challenge: Optimizing vCD34 + in cryopreserved HPC samples for implementation of an external QA ProgramCOVID 문제 해결: 외부 QA 프로그램 구현을 위해 냉동보존된 HPC 샘플에서 vCD34 + 최적화Multicenter Study Published on 2022-04-012022-09-11 Journal: Cytotherapy [Category] 바이오마커, [키워드] Allogeneic Analysis approach CD34 Cell Combination condition COVID COVID-19 pandemic CRS cryopreserved reference sample cytometric dispatch distance distribution dry ice Enumeration evaluate exclusion External external quality assurance Flow followed by harmonization hematopoietic progenitor cell implementation interlaboratory comparison liquid nitrogen meeting multicenter multicenter study National nitrogen Pandemics platform proficiency testing Program Quality Quality assurance reproducibility specificity transplantation viability viable CD34(+) HPC enumeration. was performed [DOI] 10.1016/j.jcyt.2021.10.009 PMC 바로가기 [Article Type] Multicenter Study
How to accelerate the supply of vaccines to all populations worldwide? Part II: Initial industry lessons learned and detailed technical reflections leveraging the COVID-19 situation전 세계 모든 인구에 대한 백신 공급을 가속화하는 방법은 무엇입니까? 2부: COVID-19 상황을 활용한 초기 업계 교훈 및 상세한 기술적 반성Review Published on 2022-02-232022-09-11 Journal: Vaccine [Category] COVID19(2023년), SARS, 변종, 신약개발, [키워드] accelerate approaches benefit changes comparability COVID-19 COVID-19 pandemic COVID-19 situation Digital disease Diseases distribution feasible genetically modified organisms harmonization Health heterogeneity majority market offer organism pace Part pathogen Pathogens Population populations public health public health threat Quality control Regulatory Regulatory convergence Reliance Risk-based Science Science-based stability Streamline the vaccine Treatment vaccination Vaccine Vaccines variants while [DOI] 10.1016/j.vaccine.2021.12.038 PMC 바로가기 [Article Type] Review
How to accelerate the supply of vaccines to all populations worldwide? Part I: Initial industry lessons learned and practical overarching proposals leveraging the COVID-19 situation전 세계 모든 인구에 대한 백신 공급을 가속화하는 방법은 무엇입니까? 1부: COVID-19 상황을 활용한 초기 업계 교훈 및 실질적이고 포괄적인 제안Review Published on 2022-02-232022-09-11 Journal: Vaccine [Category] COVID19(2023년), SARS, 변종, [키워드] accelerate addressed approaches approval characterized comparability Control COVID-19 COVID-19 pandemic COVID-19 situation Digital Digitalization genetically modified organisms global public health globe harmonization Health authority Health crisis heterogeneity highlight lack Medicine Medicines organism pandemic Part patients Population Regulatory Regulatory convergence Reliance Risk-based Science-based shown situation stability Streamline to be done trade-off trade-offs Vaccine variants Volume [DOI] 10.1016/j.vaccine.2021.11.098 PMC 바로가기 [Article Type] Review