The role of host genetics in susceptibility to severe viral infections in humans and insights into host genetics of severe COVID-19: A systematic review
Review
[키워드] accompanied
addition
C-lectin pathways
candidate gene
Case report
caused
CCR1
CCR9
coronavirus
coronavirus endoribonuclease
COVID-19
COVID-19 case
COVID-19 GWAS
COVID-19 pathogenesis
Cytokine storm
DC-SIGN
DC-SIGN, Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin
DC-SIGNDendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin
deficiency
Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin
disease
double-strand RNA
dsRNA, double-strand RNA
dsRNAdouble-strand RNA
dysregulated
endoU, coronavirus endoribonuclease
endoUcoronavirus endoribonuclease
Evidence
explain
expression
genetic study
Genetic variant
genome wide association studies
GWAS
GWAS, genome wide association studies
GWASgenome wide association studies
Herpes Simplex Virus 1
herpses simplex encephalitis
Host
host genetics
Host immune defenses
HSE, herpses simplex encephalitis
HSEherpses simplex encephalitis
HSV-1, Herpes Simplex Virus 1
HSV-1Herpes Simplex Virus 1
Human
hypothese
IL-18
IL-18 binding protein
IL-18BP, IL-18 binding protein
IL-18BPIL-18 binding protein
immune
immune response gene
immune system
implicated
inborn errors of immunity
Inclusion
Inflammasome
inflammasome activation
Interaction
interferon
Interleukins
International Union of Immunological Societies
IUIS, International Union of Immunological Societies
IUISInternational Union of Immunological Societies
lactate dehydrogenase
latency
LDH, lactate dehydrogenase
LDHlactate dehydrogenase
lectin
manifestation
medical subject heading
MeSH, medical subject heading
MeSHmedical subject heading
Meta-analysis
minor allele frequency
NLRP1
objective
OMIM, Online Mendelian Inheritance in Man (OMIM)
OMIMOnline Mendelian Inheritance in Man (OMIM)
Online Mendelian Inheritance in Man (OMIM)
Pathogenesis
pathway
Pathways
PBMCs, peripheral blood mononuclear cells
PBMCsperipheral blood mononuclear cells
Peripheral blood mononuclear cells
Protein
reported
Result
SARS Coronavirus
SARS coronavirus 2
SARS-coronavirus 2
SARS-CoV
SARS-CoV-2
SARS-CoV-2, SARS Coronavirus 2
SARS-CoV-2SARS Coronavirus 2
SARS-CoV, SARS Coronavirus
SARS-CoVSARS Coronavirus
severe COVID-19
Study design
susceptibility
systematic review
therapeutic targets
TLR pathway
TLR pathways
treatment for COVID-19
variant
viral disease
viral infection
Viral susceptibility
[DOI] 10.1016/j.virusres.2020.198163 PMC 바로가기 [Article Type] Review
[DOI] 10.1016/j.virusres.2020.198163 PMC 바로가기 [Article Type] Review