hierarchical clustering

[키워드] Activation Acute respiratory failure cause CD4+ CD8+ clinical trial Cluster Clustering complement Complement activation conducted coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient Critical Critical care Critically ill critically ill COVID-19 patients cytokine cytokine level cytokine release elevated eligibility endothelial enrolled evaluated exaggerated inflammatory response exhibiting favor feature France group heterogeneous Hierarchical hierarchical clustering Hypogammaglobulinemia ICU ICU admission identification IL-1β IL-6 IL-8 Ill immunodeficiency immunologically immunology immunophenotype Infection Inflammation inflammatory reaction lung damage marker mediators moderate multi-organ dysfunction Necrosis outcomes Patient patient identification patients phenotype predominant principal components principal components analysis Profiling Prospective Study respiratory Respiratory failure response to therapies SARS-CoV-2 SARS-COV-2 infection SC5b-9 Severe acute respiratory syndrome severe acute respiratory syndrome-coronavirus-2 severe COVID-19 severity shown single-center targeted therapy therapeutic therapy Trajectories tumor necrosis tumor necrosis factor tumor necrosis factor-alpha Variability variable
[DOI] 10.1016/j.chest.2020.11.049 PMC 바로가기 [Article Type] Article