Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesisSARS-CoV-2의 뉴클레오캡시드 돌연변이는 복제 및 병인을 증가시킵니다Article Published on 2022-06-212022-09-11 Journal: PLoS Pathogens [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료법, [키워드] Ablation Alanine alanine substitution Alpha component ENhance fitness Genetic variation GSK-3 human infection in vitro in vivo increase Infection molecular basis motif mutant Mutation nucleocapsid nucleocapsid protein Omicron variant Omicron variants pandemic Pathogenesis pathogenesis of SARS-CoV-2 Phosphorylation Protein Replication residue residues SARS-CoV-2 SARS-CoV-2 replication spike gene the SARS-CoV-2 Transmission variable region variant Viral Viral RNA virus replication while [DOI] 10.1371/journal.ppat.1010627 PMC 바로가기 [Article Type] Article
Antibodies from convalescent plasma promote SARS-CoV-2 clearance in individuals with and without endogenous antibody response회복기 혈장의 항체는 내인성 항체 반응이 있거나 없는 개인에서 SARS-CoV-2 제거를 촉진합니다Clinical Trial Published on 2022-06-152022-09-11 Journal: The Journal of Clinical Investigation [Category] COVID19(2023년), MERS, SARS, 임상, 진단, 치료기술, [키워드] 95% CI absence Adaptive immunity adjusted hazard ratio adverse events affected antibody Antibody Response clearance Clinical research Comorbidity Comprehensive conducted convalescent plasma Convalescent plasma therapy Corona COVID-19 Critical demonstrated disease status Efficacy evidenced faster hazard ratio hospitalized COVID-19 patient human infection human infections Immunotherapy individual Innovation Intervention IQR Kaplan-Meier analysis laboratory parameter median interval Mortality neutralization Neutralizing neutralizing antibody onset of symptom parameter Phase I plasma plasma therapy pool principle priority Program promote recipient recipients Red respond Safe SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 clearance SARS-CoV-2 vaccines serological significantly survival therapeutic Therapeutics Therapeutics. therapy transfusion-related adverse event transfusion-related adverse events Trial university University of Zurich Viral viral clearance Viral load Viremia Virological virus clearance [DOI] 10.1172/JCI158190 PMC 바로가기 [Article Type] Clinical Trial
Evolution of the human pathogenic lifestyle in fungi Reviews Published on 2022-05-042022-10-05 Journal: Nature Microbiology [Category] 유전자 메커니즘, [키워드] contribute contributed death develop drug ecological elements Evolution fungal fungal pathogen fungi Genetic genetic difference Genetic variation helping human infection insight mechanism pathogen pathogenic pathogenicity predict resulting traits understanding [DOI] 10.1038/s41564-022-01112-0 [Article Type] Reviews
Human infection with a reassortant swine-origin influenza A(H1N2)v virus in Taiwan, 2021Research Published on 2022-04-072023-06-23 Journal: Virology Journal [Category] 신종인플루엔자, [키워드] H1N2v human infection reassortant Swine influenza [DOI] 10.1186/s12985-022-01794-2 PMC 바로가기 [Article Type] Research
Human infection with avian-origin H5N6 influenza a virus after exposure to slaughtered poultryArticle Published on 2022-03-122023-05-31 Journal: Emerging Microbes & Infections [Category] Fulltext, 조류인플루엔자, [키워드] A (H5N6) virus Avian influenza virus genomic characterization human infection slaughtered poultry [DOI] 10.1080/22221751.2022.2048971 PMC 바로가기
SARS-CoV-2 outbreaks on Danish mink farms and mitigating public health interventionsCovid-19 Published on 2022-02-082022-11-01 Journal: The European Journal of Public Health [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] acute respiratory syndrome affected appear applied Combination coronavirus Denmark disease Effect effective Effectiveness Epidemic epidemiological evaluate Evidence human disease human infection human SARS-CoV-2 identify incidence rate incidence rates increase in Infection information initial Local lockdown lockdowns mitigate neutralize outbreak Public health intervention reduce Region reported Result SARS-CoV-2 SARS-COV-2 infection significant increase significantly Spread Surveillance tested Week [DOI] 10.1093/eurpub/ckab182 PMC 바로가기 [Article Type] Covid-19
Emergence of epidemic diseases: zoonoses and other originsReview Article Published on 2022-01-182022-10-31 Journal: Faculty Reviews [Category] COVID-19, [키워드] bats bottleneck COVID-19 disease emergence Epidemic Epidemics Evidence example exotic history of disease Human human infection Infection Infectious diseases Interaction origin Outbreaks overcome Pandemics risk selected Surveillance zoonose zoonosis zoonotic [DOI] 10.12703/r/11-2 PMC 바로가기 [Article Type] Review Article
SARS-CoV-2 challenge studies: ethics and risk minimisationCurrent Controversy Published on 2021-12-252022-10-30 Journal: Journal of medical ethics [Category] COVID-19, [키워드] accelerate approach assessment cause clinical implication clinical trials COVID-19 COVID-19 incidence criteria Critical develop effective effective vaccine epidemiological Ethics evaluate exceptional global public health healthy volunteer human infection infecting pathway raised Recognition Research Research Ethics risk SARS-CoV-2 scientific research Treatment virus [DOI] 10.1136/medethics-2020-106504 PMC 바로가기 [Article Type] Current Controversy
Independent infections of porcine deltacoronavirus among Haitian childrenArticle Published on 2021-11-172022-10-30 Journal: Nature [Category] Coronavirus, Fulltext, MERS, 조류인플루엔자, [키워드] acute undifferentiated Affect alphacoronavirus analysis betacoronavirus binding caused changes in children Computational biology and bioinformatics Contact coronavirus coronavirus Epidemics family Coronaviridae febrile illness genes encoding groups Haiti highlight host cell receptor human infection identify independent Infection pathogen plasma sample Porcine deltacoronavirus predict Protein reported reservoir S1 subunit SARS-CoV-2 SARS-CoV-2 pandemic spike glycoprotein strain Structural analysis the receptor-binding domain viral lineage zoonose zoonotic spillover zoonotic transmission [DOI] 10.1038/s41586-021-04111-z PMC 바로가기 [Article Type] Article
First human infection of avian influenza A(H5N6) virus reported in Lao People’s Democratic Republic, February–March 2021Article Published on 2021-11-102023-05-31 Journal: Influenza and Other Respiratory Viruses [Category] Fulltext, 조류인플루엔자, [키워드] H5N6 subtype human infection influenza A virus Laos poultry rapid response team [DOI] 10.1111/irv.12934 PMC 바로가기