Antibody responses to the SARS-CoV-2 vaccines in hemodialysis patients: Is inactivated vaccine effective?혈액투석 환자에서 SARS-CoV-2 백신에 대한 항체 반응: 불활성화 백신이 효과적인가?Article Published on 2022-08-012022-09-11 Journal: Therapeutic apheresis and dialysis : official peer [Category] MERS, SARS, 진단, 치료기술, [키워드] antibody antibody level antibody levels Antibody Response carried Comparative control group COVID-19 detected antibody dose Effectiveness General population generate healthy volunteers Hemodialysis humoral Humoral response humoral responses immunization inactivated Inactivated vaccine investigated Maintenance hemodialysis mRNA mRNA vaccine mRNA vaccines Patient patients Receptor binding domain reduced SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 vaccine SARS-CoV-2 vaccines Seropositivity significantly lower Spike protein symptomatic infection the SARS-CoV-2 Vaccine vaccine group Vaccines were measured while [DOI] 10.1111/1744-9987.13752 PMC 바로가기 [Article Type] Article
Autoantibodies in COVID-19 correlate with antiviral humoral responses and distinct immune signaturesCOVID-19의 자가항체는 항바이러스 체액 반응 및 뚜렷한 면역 신호와 상관관계가 있습니다Article Published on 2022-08-012022-09-11 Journal: Allergy [Category] COVID19(2023년), SARS, 바이오마커, 진단, 치료기술, 치료제, [키워드] acute COVID-19 acute disease acute SARS-CoV-2 infection alteration antibody Antibody titer Antibody titers antineutrophil cytoplasmic antibodies antinuclear antibodies Antiviral association autoantibodies autoantibody Autoimmune autoimmune pathology B-cell breadth clinically Cohort Comorbidities comparable controls coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 patient COVID-19 patients cross-reactive cytoplasmic demonstrated detect disease disease course exhibited feature healthy controls humoral immune response Humoral response humoral responses immune immune responses immune signature Immunity immunofluorescence assay implication indirect immunofluorescence individual Infection Inflammatory occur other coronavirus other coronaviruses Paired analysis Patient patients performed Prevalence proteomics SARS-CoV-2 screened serological serum severe COVID-19 severity of COVID-19 subgroup of patient trajectory vaccinated individuals VirScan [DOI] 10.1111/all.15302 PMC 바로가기 [Article Type] Article
Interdependencies of cellular and humoral immune responses in heterologous and homologous SARS-CoV-2 vaccination이종 및 동종 SARS-CoV-2 백신 접종에서 세포 및 체액성 면역 반응의 상호 의존성Observational Study Published on 2022-08-012022-09-11 Journal: Allergy [Category] COVID19(2023년), MERS, SARS, 임상, 진단, 치료기술, [키워드] Anti-spike Antibody avidity association avidity blood sample Blood samples BNT162b2 booster booster vaccination cellular Cellular immune response cellular immune responses ChAdOx1 ChAdOx1 nCoV-19 group healthcare worker Heterologous homologous humoral Humoral and cellular immune responses humoral immune response humoral responses IgG levels immune immune response immune responses immunization interferon interferon-γ nCoV Neutralizing antibodies neutralizing antibody no significant differences Observational cohort study SARS-CoV-2 SARS-CoV-2 vaccination secondary immunization significant difference significant differences Spike protein T-cell T-cell activation T-cell Response T-cell responses unlikely vaccination [DOI] 10.1111/all.15247 PMC 바로가기 [Article Type] Observational Study
Increased neutralization and IgG epitope identification after MVA-MERS-S booster vaccination against Middle East respiratory syndrome Research Published on 2022-07-192022-10-05 Journal: Nature Communications [Category] 바이오마커, 임상, [키워드] antibody Antibody titer baseline binding booster vaccination clinical trial conducted coronavirus epitope Epitopes evaluate exploratory expressing homologous humoral responses identify IgG immunization immunogenic Increased magnitude MERS-CoV Middle East neutralization Neutralizing pandemic participant Phase 1 RBD respiratory syndrome coronavirus responses S2 subunit Safe spike glycoprotein Support syndrome the receptor-binding domain trial participant trials two-dose regimen vaccination vaccine candidate [DOI] 10.1038/s41467-022-31557-0 [Article Type] Research
Immune responses in Omicron SARS-CoV-2 breakthrough infection in vaccinated adults백신 접종 성인의 Omicron SARS-CoV-2 돌발성 감염의 면역 반응Article Published on 2022-07-182022-09-11 Journal: Nature Communications [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] activated antibody antigens B cell B cell response Breakthrough infection breakthrough infections Cell cells cellular immunity circulation Cytotoxic T cells de novo follicular functional humoral humoral responses Immunity individual Infection memory B cell memory B cells memory T memory T cell Mutation omicron participant plasmablast PROTECT Protein RBD-specific IgG recall Receptor binding domain response robust SARS-CoV-2 significantly increased spike Spike protein T cell T cell response T cell responses T cells the Spike Transmissibility vaccinated individuals vaccine immunity Vaccines variant Viral viral antigens viral escape wild type [DOI] 10.1038/s41467-022-31888-y PMC 바로가기 [Article Type] Article
Heterologous saRNA Prime, DNA Dual-Antigen Boost SARS-CoV-2 Vaccination Elicits Robust Cellular Immunogenicity and Cross-Variant Neutralizing Antibodies이종 saRNA 프라임, DNA 이중 항원 부스트 SARS-CoV-2 백신 접종으로 강력한 세포 면역원성과 교차 변형 중화 항체 유도Article Published on 2022-07-152022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료법, [키워드] Adenovirus animal model animal models B.1.617.2 Beta boost CD4+ CD8+ T-cell combinations COVID-19 D614G mutation Delta distribution DNA dual dual antigen ENCODE enhanced expression followed by furin furin cleavage region Glutamine Heterologous highest homologous homologous or heterologous Humoral response humoral responses IgG immune response immune responses immunogenicity lipid carrier MHC class I MHC class I and II mice motif N antigen Neutralizing nucleic acid nucleocapsid omicron peptide peptides prefusion conformation prime proline prolines protease pseudovirus receiving regimen regimens Region response RNA vaccine SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant self-amplifying RNA sequence sera serotype spike Stimulation strain Strains Support T-cell T-cell responses vaccination Vaccine Vaccines variant wild type Wuhan [DOI] 10.3389/fimmu.2022.910136 PMC 바로가기 [Article Type] Article
Recent advances in clinical practice: management of inflammatory bowel disease during the COVID-19 pandemic임상 실습의 최근 발전: COVID-19 대유행 중 염증성 장 질환 관리Review Published on 2022-07-012022-09-11 Journal: Gut [Category] COVID19(2023년), SARS, 치료기술, [키워드] acquisition adverse outcome adverse outcomes antibody booster dose bowel Breakthrough infection breakthrough infections Cancer cancers Corticosteroid Corticosteroids COVID-19 COVID-19 in patient COVID-19 pandemic Crohn's disease de novo decrease develop diagnoses disease course dose Evidence Future General population Guidance hospitalisation hospitalisations Humoral response humoral responses IBD immune immune response immunosuppressive therapies immunosuppressive therapy increased risk Inflammatory Inflammatory bowel disease management medication medications Necrosis outcome outcomes pandemic Patient patients potential risk primary dose raised receive recent remained Research risk risk of COVID-19 SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 vaccines TNF treated Treatment ulcerative ulcerative colitis Vaccine vaccine response Vaccines [DOI] 10.1136/gutjnl-2021-326784 PMC 바로가기 [Article Type] Review
A Fourth Dose of COVID-19 Vaccine Does Not Induce Neutralization of the Omicron Variant Among Solid Organ Transplant Recipients With Suboptimal Vaccine ResponseCOVID-19 백신의 4차 접종은 최적의 백신 반응을 보이지 않는 고형 장기 이식 수혜자들 사이에서 오미크론 변이체의 중화를 유도하지 않습니다Article Published on 2022-07-012022-09-11 Journal: Transplantation [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome angiotensin angiotensin-converting enzyme 2 anti-receptor-binding domain Anti-spike anti-spike antibody anti-Spike IgG Antibody Units binding antibody units booster vaccinations change Cohort coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccine Delta delta variant domain dose ELISA full-length spike protein Health Organization healthy controls high risk Humoral response humoral responses IgG immune evasion Immunoglobulin increase Infection interquartile range Intervention Live virus median multiplex neutralization neutralizing capacity omicron Omicron variant Protective recipient respiratory response Seropositivity significantly increased significantly lower Solid solid organ solid organ transplant Spike proteins surrogate the vaccine Transplant Vaccination strategy Vaccine vaccine dose vaccine strain variant VoC VOCs was measured Wilcoxon signed-rank test World Health Organization [DOI] 10.1097/TP.0000000000004140 PMC 바로가기 [Article Type] Article
Immune Responses to SARS-CoV-2 Vaccination in Young Patients with Anti-CD19 Chimeric Antigen Receptor T Cell-Induced B Cell Aplasia항-CD19 키메라 항원 수용체 T 세포 유도 B 세포 무형성증이 있는 젊은 환자에서 SARS-CoV-2 백신 접종에 대한 면역 반응Article Published on 2022-07-012022-09-11 Journal: Transplantation and cellular therapy [Category] COVID19(2023년), MERS, SARS, 바이오마커, 변종, 진단, 치료기술, [키워드] Acute lymphoblastic leukemia acute respiratory syndrome acute respiratory syndrome coronavirus advent adverse events age Anti-CD19 Anti-CD19 CAR T cell-induced B cell aplasia anti-S Antigen antigen receptor aplasia B cell CAR CAR T cell therapy CD19 CD4 CD4/CD8 Cell therapy cellular immunity chimeric antigen receptor Cohort coronavirus coronavirus disease coronavirus disease 19 COVID-19 Cytometry deficiency diagnosed disease Endpoint Exacerbation exhibited expected flow cytometry grade 3 Graft-versus-host disease GVHD healthy healthy controls humoral Humoral response humoral responses Immune cell immune response Immunoglobulin Immunoglobulin G incidence individual induce Infection leukemia Lymphoblastic leukemia lymphocyte Lymphocyte count Lymphocyte subsets mRNA vaccine Mutation Omicron variant outcome Patient precursor primary endpoint Prospective Study PROTECT protective effect recipient Relapse respiratory response risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination second dose secondary Secondary endpoints Seroconversion severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spike protein subsequent T cell T cell response T cell responses T cells T-cell the patient the vaccine therapy treated vaccination Vaccine [DOI] 10.1016/j.jtct.2022.04.017 PMC 바로가기 [Article Type] Article
A guide to investigating immune responses elicited by whole-sporozoite pre-erythrocytic vaccines against malariaarticle Published on 2022-06-302024-09-01 Journal: The FEBS Journal [Category] 말라리아, [키워드] antibodies Cellular responses Controlled human malaria infection humoral responses Immunity liver Lymphocytes P. falciparum Plasmodium vaccination [Article Type] article