What Open-Lung Biopsy Teaches Us about ARDS in COVID-19 Patients: Mechanisms, Pathology, and Therapeutic Implications개폐 생검이 COVID-19 환자의 ARDS에 대해 가르치는 것: 기전, 병리학 및 치료적 의미Research Article Published on 2020-12-092022-09-10 Journal: BioMed Research International [Category] 치료기술, [키워드] acute respiratory distress syndrome alveolar damage Analysis Anticoagulant ARDS assist Atypical Berlin biopsy cause caused chain Chain Reaction Coagulopathy Compliance COVID-19 Culture dead Dead space difficulty dual FIBRIN Glucocorticoids High dose hyaline membrane hyaline membranes Hypoxemia Injury intensive care intensive care unit lung lung tissue mechanical ventilation meet microthrombi pathophysiology Patient patients physician pleural fluid polymerase chain reaction Protective pulmonary parenchyma reaction researcher respiratory respiratory distress Respiratory distress syndrome RT-PCR SARS-CoV-2 severe hypoxemia Shunt shunt effect specimens Therapeutic approach thrombotic tissue biopsy two patients understanding vascular congestion Ventilation-perfusion ratio was performed [DOI] 10.1155/2020/2909673 PMC 바로가기 [Article Type] Research Article
COVID-19 pulmonary pathology: a multi-institutional autopsy cohort from Italy and New York City Research Published on 2020-09-022022-10-05 Journal: Modern pathology : an official journal of the Unit [Category] SARS, 진단, [키워드] acute respiratory distress airway epithelium airways alveolar alveolar damage Autopsy Cohort conditions contribute correlated COVID-19 Culture cytoplasmic DAD determine Diagnosis diffuse disease endothelial evaluated feature Features female global pandemic heterogeneous histologic hyaline membranes IHC immunohistochemistry independent Infection Inflammation initial Injury intubation involved Italy less lung lung damage male median age membrane Microscopy microthrombi Mortality New York City Patient Platelet Pneumocytes Pneumonia positive RNA SARS-CoV-2 SARS-CoV-2 viral small vessel Spike protein subset syndrome three centers Tracheobronchitis USA vacuolization Vascular injury vasculature vessel viral culture virus was performed [DOI] 10.1038/s41379-020-00661-1 [Article Type] Research