Using EHR data to identify coronavirus infections in hospitalized patients: Impact of case definitions on disease surveillanceArticle Published on 2022-10-012022-11-15 Journal: International journal of medical informatics [Category] COVID19(2023년), SARS, 치료제, [키워드] age and sex anti-IL6 Antiviral Case definition Characteristics Clinical diagnosis clinically cohort characteristics Complication coronavirus disease Coronavirus infection COVID COVID-19 diagnosed Disease surveillance EHR data Electronic health records. evaluate evaluated Health health system Hospitalized Hydroxychloroquine identify Impact Inpatient lab Laboratory laboratory confirmation Laboratory test laboratory-confirmed Myocardial infarction outcome outcomes overall mortality Patient patients hospitalized positive receive Record required SARS-CoV-2 The United States therapy with COVID-19 [DOI] 10.1016/j.ijmedinf.2022.104842 PMC 바로가기
Novel corona virus (COVID-19) pandemic: current status and possible strategies for detection and treatment of the diseaseReview Published on 2022-10-012023-07-06 Journal: Expert review of anti-infective therapy [Category] COVID19(2023년), SARS, [키워드] Corona virus Hydroxychloroquine pandemic Remdesivir vaccine. [DOI] 10.1080/14787210.2021.1835469 PMC 바로가기 [Article Type] Review
Prevalence of ECG testing and characteristics among new hydroxychloroquine and chloroquine users within a multi-center tertiary care centerArticle Published on 2022-10-012022-11-16 Journal: Rheumatology International [Category] COVID19(2023년), SARS, 치료기술, [키워드] affected Arrhythmias baseline cardiac Cardiotoxicity Care Characteristics Chloroquine COVID-19 develop ECG Electrocardiography Electronic health records examined Factor female Follow-up Frequency HCQ Hydroxychloroquine Hydroxychloroquine. initial male management medical system Myocardial infarction Older Patient populations Prospective QTc QTC prolongation raised rheumatic disease subject therapy [DOI] 10.1007/s00296-022-05125-0 PMC 바로가기
Ivermectin role in COVID-19 treatment (IRICT): single-center, adaptive, randomized, double-blind, placebo-controlled, clinical trialRandomized Controlled Trial Published on 2022-10-012023-07-09 Journal: Expert review of anti-infective therapy [Category] COVID19(2023년), [키워드] clinical trial COVID-19 Efficacy Hydroxychloroquine Ivermectin Safety. [DOI] 10.1080/14787210.2022.2098113 PMC 바로가기 [Article Type] Randomized Controlled Trial
In vitro evaluation of the impact of Covid-19 therapeutic agents on the hydrolysis of the antiviral prodrug remdesivirResearch article Published on 2022-09-012022-10-05 Journal: Chemico-biological interactions [Category] 변종, 치료제, [키워드] Activation analyzed Anti-inflammatory drugs Antibiotics Antiviral appear AUC cannabidiol carboxylesterase 1 carrier CES1 clearance clinical study COVID-19 Dexamethasone enzyme evaluate evaluated fraction G143E hospitalized patient hydrolysis Hydroxychloroquine impairment in vitro in vitro study in vivo indicated individual inhibit inhibitor Interaction Ivermectin mechanism medication metabolism nine partial inhibition pharmacokinetic polymorphism produced RDV recent reduction Remdesivir required substrates suggested therapeutic agent treating COVID-19 Treatment unlikely variant with COVID-19 [DOI] 10.1016/j.cbi.2022.110097 [Article Type] Research article
Does the public know when a scientific controversy is over? Public perceptions of hydroxychloroquine in France between April 2020 and June 2021Article Published on 2022-09-012022-11-15 Journal: Thérapie [Category] SARS, 치료제, [키워드] asked association Chloroquine collected conducted Consensus consequence coronavirus disease Coverage COVID-19 derivative died early stage effective Effectiveness Efficacy Evolution Factor France French Government HCQ Hydroxychloroquine investigated Logistic regression majority media pandemic proportion Public public attitude question respondent Scientific community Sociodemographic Sociology Surveys. therapeutic variable [DOI] 10.1016/j.therap.2022.01.008 PMC 바로가기
Repurposing drugs and identification of inhibitors of integral proteins (spike protein and main protease) of SARS-CoV-2SARS-CoV-2의 필수 단백질(스파이크 단백질 및 주요 프로테아제) 억제제의 용도 변경 및 식별Article Published on 2022-09-012022-09-11 Journal: Journal of biomolecular structure & dynamics [Category] SARS, 신약개발, [키워드] analysis binding energy Cefoperazone Clinical use Compound Coronavirus infection COVID-19 docked domain drug effort EGCG Emergency exhibited FIVE glycoprotein GRN HCQ Hydroxychloroquine identify Infection inhibitor inhibitors inhibitors of SARS-CoV-2 Inhibitory effects Lopinavir LPV M pro main protease enzyme MDs molecular molecular docking molecular dynamic simulations MPro nelfinavir outbreak predicted protease Protein Public public health emergency RBD RDV Receptor-binding domain recorded Remdesivir repurposing SARS-CoV SARS-CoV-2 SARS-CoV-2 spike protein screened spike (S) glycoprotein. Spike protein were used WHO World Health Organisation Zafirlukast [DOI] 10.1080/07391102.2021.1886993 PMC 바로가기 [Article Type] Article
Efficacy of pharmacological interventions in COVID-19: A network meta-analysisCovid-19의 약리학 적 개입의 효능 : 네트워크 메타 분석Meta-Analysis Published on 2022-09-012022-09-08 Journal: British Journal of Clinical Pharmacology [Category] meta-analysis, 임상, 치료제, [키워드] 95% confidence interval Administered analysed Clinical improvement clinical recovery Controlled trial coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 database Dexamethasone drug Favipiravir followed by head Head-to-head comparison Hydroxychloroquine increase interferon Intervention investigator Lopinavir Lopinavir/ritonavir lower mortality lower risk lower risk of mortality MeSH term moderate to severe Mortality Network meta-analysis Occurrence patients with moderate pharmacological intervention Quantitative analysis Randomized controlled trial reduce reduced Relative risk Remdesivir remdesivir. risk Ritonavir screened Serious Adverse Event Serious Adverse Events severe COVID-19 significantly Standard of care Tocilizumab was performed [DOI] 10.1111/bcp.15338 PMC 바로가기 [Article Type] Meta-Analysis
COVID-19 in Latin America and the Caribbean: Two years of the pandemic라틴 아메리카와 카리브해의 COVID-19: 전염병의 2년Review Published on 2022-09-012022-09-11 Journal: Journal of internal medicine [Category] COVID19(2023년), SARS, 변종, [키워드] catastrophic coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccination death determinant determinants drug facilitated Factor Gamma global health Healthcare systems herd immunity Hydroxychloroquine Immunity Ivermectin Lambda Latin Latin America misinformation pandemic Prevent reported SARS-CoV-2 security social distancing measures Spread Support treat vaccination vaccination. variant virus while [DOI] 10.1111/joim.13499 PMC 바로가기 [Article Type] Review
Ultraviolet-coupled advanced oxidation processes for anti-COVID-19 drugs treatment: Degradation mechanisms, transformation products and toxicity evolutionResearch article Published on 2022-09-012022-10-05 Journal: Chemosphere [Category] 치료기술, 치료법, 치료제, [키워드] Analysis anti-COVID-19 drugs Appropriate Bacterial Combined COVID-19 Degradation degradation mechanism Dexamethasone drug Evolution functional H2O2 HCQ Hydroxychloroquine Intermediates analysis investigated Luminescence Luminescent bacterial test mechanisms parameter pathway Pneumonia positive predicted RDV Remdesivir risk significantly higher Toxicity Treatment UV/AOPs viruses [DOI] 10.1016/j.chemosphere.2022.134968 [Article Type] Research article