Dual-detection fluorescent immunochromatographic assay for quantitative detection of SARS-CoV-2 spike RBD-ACE2 blocking neutralizing antibodySARS-CoV-2 스파이크 RBD-ACE2 차단 중화 항체의 정량적 검출을 위한 이중 검출 형광 면역크로마토그래피 분석Article Published on 2022-03-012022-09-11 Journal: Biosensors & bioelectronics [Category] MERS, SARS, 변종, 진단, 치료기술, [키워드] ACE2 affinity Algorithm Analysis analyte angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 assays binding Biomarkers Care Community Comparative analysis convalescent plasma COVID-19 pandemic detect Dual-detection effort ELISA kit fluorescent Immunity immunochromatographic immunochromatographic assay Immunoglobulin immunoglobulins IMPROVE incorporation indicated Lateral lateral flow assay linear Neutralization antibody Neutralizing antibodies neutralizing antibody Point point of care testing positive positive result Precision provide Quantitative Rapid test Ratiometric biosensor RBD RBD-ACE2 Reactions Receptor-binding domain recipients revaccination SARS CoV SARS CoV-2 SARS CoV-2. SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 neutralizing antibodies SARS-CoV-2 neutralizing antibody SARS-CoV-2 spike SARS-CoV-2 spike protein sensitivity serum sample Spike protein the RBD the receptor-binding domain the SARS-CoV-2 vaccination Vaccinations Vaccine Viral Viral variants [DOI] 10.1016/j.bios.2021.113883 PMC 바로가기 [Article Type] Article
Clinical Evidence Informing Treatment Guidelines on Repurposed Drugs for Hospitalized Patients During the Early COVID-19 Pandemic: Corticosteroids, Anticoagulants, (Hydroxy)chloroquine초기 CovID-19 Pandemic 동안 입원 환자를위한 용도로 된 약물에 대한 치료 지침에 대한 임상 증거 : 코르티코 스테로이드, 항응고제, (Hydroxy) 클로로퀸Review Published on 2022-02-182022-08-31 Journal: Frontiers in Public Health [Category] COVID19(2023년), meta-analysis, SARS, 임상, [키워드] adoption analysis Analysis Anticoagulants best Chloroquine clinical Clinical data clinical evidence Clinical studies clinical study clinical trials Coagulopathy competing conducted coronavirus disease Coronavirus disease 2019 Corticosteroids COVID-19 drug Efficacy and safety evaluated Evidence evidence generation Factor Factors Germany guideline Health Organization hospital hospitalized COVID-19 patient hospitalized COVID-19 patients hydroxy identify incorporation Inflammation Informing International meta-analyses meta-analysis MOST National national treatment observational studies pandemic Patient care platform Platform trial platform trials protocol provided question randomized clinical trial RCT RCTs recommendations referred to Repurposed drug Repurposed drugs researcher Result retrospective cohort retrospective cohort study robust scientific rigor severely ill patient severely ill patients Spread Treatment treatment guideline treatment guidelines trials United State United States Viral viral replication WHO World Health Organization [DOI] 10.3389/fpubh.2022.804404 PMC 바로가기 [Article Type] Review
Classical and Next-Generation Vaccine Platforms to SARS-CoV-2: Biotechnological Strategies and Genomic VariantsSARS-CoV-2에 대한 고전 및 차세대 백신 플랫폼: 생명공학 전략 및 게놈 변이Review Published on 2022-02-182022-09-10 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), MERS, SARS, 변종, 유전자 메커니즘, [키워드] aAPC Ad5-nCoV adaptive Amino acid amino acids animals antibody applied B.1.1.7 B1.351 BBIBP-CorV bind Biotechnology BNT Cell classical clinical trial consequence CoronaVac coronavirus COVID-19 COVID-19 vaccine COVID-19 vaccines CoVs D614G Deletion demonstrated dendritic cell dendritic cells domain escape Evolution genomic variant genomic variants HCoV HCoV-229E HCoV-HKU1 HCoV-NL63 HCoV-OC43 high affinity HKU1 hosts Human humans inactivated incorporation inhibit INO-4800 JNJ-78436735 lentiviral Lentiviral vector LV-SMENP-DC MERS-CoV molecular mRNA mRNA-1273 mutated nCoV New new SARS-CoV-2 new strain NL63 NVX-CoV2373 vaccine P.1 pathogen Pathogens platform Protein RBD receptor ACE2 Receptor-binding domain recombinant vaccine recombinant vaccines replacement residue responsible RNA vaccines S protein SARS-CoV SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 variants strain Strains Strategy subunits technological platforms tested the S protein Transmissibility trials Vaccine vaccine production Vaccines variant variants variety Viral virus-like particles β-coronavirus β-CoV β-CoVs [DOI] 10.3390/ijerph19042392 PMC 바로가기 [Article Type] Review
A Comprehensive Review of the Technological Solutions to Analyse the Effects of Pandemic Outbreak on Human Lives전염병 발병이 인간의 삶에 미치는 영향을 분석하기 위한 기술 솔루션에 대한 종합적인 검토Review Published on 2022-02-182022-09-10 Journal: Medicina [Category] COVID19(2023년), MERS, SARS, 치료기술, [키워드] affected Analysis artificial artificial intelligence attacks augmented reality behavioural Blockchain boost caused combating Comprehensive coronavirus COVID-19 COVID-19 outbreak COVID-19 pandemic domain Drug development Economy Effect ENhance fake news healthcare healthcare service Healthcare systems help highlight Human human lives incorporation increase intelligence Internet Internet of Things life Life expectancy medical supply offer outbreak Outbreaks overcome pandemic Pandemics Patient Predictive privacy promote public health emergency REALITY Research respond resulting review robust sanitising SARS-CoV-2 security social social distancing solution Supply chain use cases virtual reality virus [DOI] 10.3390/medicina58020311 PMC 바로가기 [Article Type] Review
Anatomy education in US Medical Schools: before, during, and beyond COVID-19Research Published on 2022-02-162022-10-28 Journal: BMC Medical Education [Category] Coronavirus, COVID19(2023년), Fulltext, MERS, SARS, [키워드] Anatomy anticipated asked cadaver change changes concerning Course COVID-19 COVID-19 pandemic decrease FIVE fraction highlight implementation incorporation lack MOST question reported Result School social distancing supplementary material sustained technology [DOI] 10.1186/s12909-022-03177-1 PMC 바로가기 [Article Type] Research
Using dipstick urinalysis to predict development of acute kidney injury in patients with COVID-19COVID-19 환자에서 급성 신장 손상의 발병을 예측하기 위해 딥 스틱 소변 검사 사용Research Published on 2022-02-012022-09-01 Journal: BMC Nephrology [Category] MERS, 진단, [키워드] 95% confidence interval Accuracy Acute kidney injury added Admission AKI AUC baseline chronic Chronic kidney disease CKD COVID-19 creatinine Dipstick during admission help Hematuria hospitalized patient hospitalized patients hospitals incorporation increase increased risk individuals kidney Kidney disease Kidney injury on admission outcome patients patients hospitalized patients with COVID-19 PCR positive predict Predictive model predictive models Presence Prognostic value Proteinuria renal replacement therapy replacement therapy respiratory Result RRT SARS-CoV2 serum creatinine severity significantly increased supplementary material Urinalysis were used with COVID-19 [DOI] 10.1186/s12882-022-02677-y PMC 바로가기 [Article Type] Research
Lateral flow–based nucleic acid detection of SARS-CoV-2 using enzymatic incorporation of biotin-labeled dUTP for POCT usePOCT 사용을위한 비오틴-표지 된 DUTP의 효소 혼입을 사용하여 SARS-COV-2의 측면 유동 기반 핵산 검출Communication Published on 2022-01-192022-09-01 Journal: Analytical and bioanalytical chemistry [Category] COVID19(2023년), Fulltext, SARS, 진단, 치료기술, [키워드] Abstract Accuracy Biotin cDNA Combination COVID-19 COVID-19 pandemic Data analysis detrimental effect detrimental effects develop diagnostic effort FITC immunochromatographic incorporation indicate isothermal isothermal amplification LAMP Lateral lateral flow Lateral flow assay (LFA) Loop-mediated isothermal amplification N-gene nucleic acid nucleic acid amplification Nucleic acid detection overcome Pandemics Pathogens POCT point of care Point of care testing (POCT) positive primer Rapid reduced Research research and development reverse transcriptase Reverse transcription loop-mediated isothermal amplification (RT-LAMP) RNA sample RNA samples RT-LAMP SARS-CoV-2 SARS-CoV-2 viral RNA SARS-CoV-2 N-gene semi-quantitative sensitive sensitivity Specific specificity supplementary material tested Viral Viral RNA [DOI] 10.1007/s00216-022-03880-4 PMC 바로가기 [Article Type] Communication
Impaired Folate-Mediated One-Carbon Metabolism in Type 2 Diabetes, Late-Onset Alzheimer’s Disease and Long COVID제2형 당뇨병, 후기 발병 알츠하이머병 및 장기 코로나에서 엽산 매개 단일 탄소 대사 장애Review Published on 2021-12-232022-09-10 Journal: Medicina [Category] SARS, 유전자 메커니즘, [키워드] Abnormalities Alzheimer’s disease Alzheimer’s disease biochemical Biomarker biosynthetic biosynthetic pathways carbon clinical disease COVID COVID-19 cytoplasm developmental diabetes Diabetes Mellitus Diseases elevated epigenetics folate functional homocysteine hyperhomocysteinemia Impaired incorporation knowledge Long Long COVID mechanism metabolic network metabolic pathway metabolic pathways metabolism Mitochondria MTHFR gene mutations nucleus nutritional B vitamin deficiencies PASC pathology pathway progression Repurposed drugs responsible SARS-CoV-2 Stress the reader Therapeutics Treatment Type type 2 diabete Type 2 diabetes mellitus Vitamin vitamins [DOI] 10.3390/medicina58010016 PMC 바로가기 [Article Type] Review
Thiol-sensitive probe enables dynamic electrochemical assembly of serum protein for detecting SARS-Cov-2 marker protease in clinical samples티올에 민감한 프로브는 임상 샘플에서 SARS-Cov-2 마커 프로테아제를 검출하기 위한 혈청 단백질의 동적 전기화학적 조립을 가능하게 합니다.Article Published on 2021-12-152022-09-11 Journal: Biosensors & bioelectronics [Category] SARS, 치료기술, 치료제, [키워드] Clinical practice clinical sample Concentration COVID-19 fluorescent incorporation Incubation induce infected patient infected patients Interaction main protease marker mimicking molecule network nucleic acid Nucleic acid detection peptide Peptide nano-network probe protease Protein Region SARS-CoV-2 sensitivity serum Serum protein serum samples spreading target target protein thiol thiol group Thiol probe. virus virus assay while [DOI] 10.1016/j.bios.2021.113579 PMC 바로가기 [Article Type] Article
[Vaccine against COVID-19][코로나19 백신]Review Published on 2021-12-012022-09-11 Journal: Revista española de quimioterapia : publicación [Category] SARS, 변종, [키워드] applied asked avalanche Cancer chance Chemotherapy COVID-19 COVID-19 pandemic disease Diseases effectiveness-safety ELLA English Evidence Health incorporation indicated Infectious disease Infectious diseases information knowledge other disease other diseases Pandemia patients peer review Practitioner practitioners produced product Psychological question SARS-CoV-2 Society Spanish Vaccine Vaccines variants variants. [DOI] 10.37201/req/085.2021 PMC 바로가기 [Article Type] Review