Novel biomarker-based score (SAD-60) for predicting mortality in patients with COVID-19 pneumonia: a multicenter retrospective cohort of 1013 patientsCOVID-19 폐렴 환자의 사망률 예측을 위한 새로운 바이오마커 기반 점수(SAD-60): 1013명의 환자로 구성된 다기관 후향적 코호트Multicenter Study Published on 2022-06-012022-09-11 Journal: Biomarkers in Medicine [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] acronym age albumin COVID-19 COVID-19 pneumonia CURB CURB-65 D-dimer death highest hospitalized patient hospitalized patients In-hospital death independent predictors male Mortality multicenter Multivariate analysis NEWS2 novel occurred oxygen oxygen saturation Patient patients patients with COVID-19 peripheral capillary Peripheral capillary oxygen saturation Pneumonia predict Predictive qSOFA representing retrospective retrospective cohort risk SAD-60 score SpO2 with COVID-19 [DOI] 10.2217/bmm-2021-1085 PMC 바로가기 [Article Type] Multicenter Study
Cytokeratin 18 cell death assays as biomarkers for quantification of apoptosis and necrosis in COVID-19: a prospective, observational studyCOVID-19에서 세포자멸사 및 괴사의 정량화를 위한 바이오마커로서의 Cytokeratin 18 세포 사멸 분석: 전향적 관찰 연구Observational Study Published on 2022-06-012022-09-11 Journal: Journal of Clinical Pathology [Category] Coronavirus, COVID19(2023년), MERS, SARS, 바이오마커, 임상, [키워드] admitted patients Adult patients Apoptosis appear assays Biomarker blood sample Blood samples Care caspase cell damage cell death clinical trials collected Control controls COVID-19 COVID-19 patient COVID-19 patients cytokeratin discharged patients elevated emergency department enrolled enzyme epithelial epithelial cell estimation hospitalisation hospitalised hospitalised COVID-19 patients ICU admission independent predictor independent predictors Intact intensive care unit mechanism multivariable logistic regression Necrosis non-ICU Patient patients patients with COVID-19 presenting quantification relative contribution relative contributions respiratory respiratory symptom respiratory symptoms risk stratification SARS-CoV-2 severe disease sick therapeutic efficacy Trigger triggers Virology [DOI] 10.1136/jclinpath-2020-207242 PMC 바로가기 [Article Type] Observational Study
An analysis of antibody response following the second dose of CoronaVac and humoral response after booster dose with BNT162b2 or CoronaVac among healthcare workers in Turkey터키 의료 종사자의 코로나백 2차 접종 후 항체 반응 및 BNT162b2 또는 코로나백 추가 접종 후 체액성 반응 분석Article Published on 2022-05-012022-09-11 Journal: Journal of medical virology [Category] Fulltext, MERS, 변종, 진단, [키워드] 95% CI 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration age Analysis Anti-RBD IgG anti-receptor-binding domain antibody antibody levels Antibody Response asked blood draw BNT162b2 booster booster dose booster doses chronic disease circulating variants Complete CoronaVac coronavirus dose evaluated Follow-up groups healthcare worker Healthcare workers Heterologous heterologous vaccination homologous or heterologous humoral Humoral response IgG Immunoglobulin Immunoglobulin G Inactivated vaccine independent predictor independent predictors levels of antibody Limited Messenger RNA Odds ratio participant Participants prospective cohort study Quantitative questionnaire RBD reduction respiratory risk SARS-CoV-2 second dose Seropositivity severe acute respiratory syndrome Coronavirus single booster dose the median Turkey university hospital vaccination Vaccine waning immunity were infected were measured [DOI] 10.1002/jmv.27620 PMC 바로가기 [Article Type] Article
Clinical features and independent predictors for recurrence of positive SARS-CoV-2 RNA: A propensity score-matched analysis양성 SARS-CoV-2 RNA의 재발에 대한 임상적 특징 및 독립적 예측인자: 성향 점수 일치 분석Article Published on 2022-04-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 치료제, [키워드] 95% CI 95% confidence interval activated acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect Analysis Blood borderline categorical variable CD3 CD4 chlorine clinic clinical confounding factors coronavirus count COVID-19 COVID-19 patient cured determine discharged elevated Factor feature hospital independent independent predictor independent predictors independent risk factor independent risk factors Logistic regression analysis marker multivariate multivariate logistic regression multivariate logistic regression analysis Odds ratio Patient positive Potassium propensity score matching prothrombinase Public recurrence regression analysis RNA SARS-CoV-2 SARS-CoV-2 RNA sensitivity analysis serum severe acute respiratory syndrome Coronavirus statistical statistically significant virus was used with COVID-19 [DOI] 10.1002/jmv.27450 PMC 바로가기 [Article Type] Article
Determinants of persistence of symptoms and impact on physical and mental wellbeing in Long COVID: A prospective cohort studyLong COVID에서 증상의 지속성과 신체적 정신적 웰빙에 미치는 영향의 결정 요인: 전향적 코호트 연구Article Published on 2022-04-012022-09-11 Journal: The Journal of Infection [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] Admission advanced age analyzed breathlessness consequence contribute COVID COVID-19 COVID-19 patients determinant Duration fatigue female gender Health Hospital admission Hospitalized ICU identify independent predictor independent predictors Long Long COVID males Mental Patient persistence physical Physical health Population predictor predictors prospective cohort prospective cohort study Psychological distress residual Residual symptoms risk factor Risk factors Symptom Symptom persistence. symptomatic Symptoms the median were assessed [DOI] 10.1016/j.jinf.2022.02.003 PMC 바로가기 [Article Type] Article
Characteristics of lymphocyte subsets and cytokine profiles of patients with COVID-19COVID-19 환자의 림프구 하위 집합 및 사이토카인 프로필의 특성Article Published on 2022-03-282022-09-11 Journal: Virology Journal [Category] 변종, 치료기술, [키워드] Abnormalities age Analysis analyzed AUC B cells Care CD19 CD3 CD4 CD8 Cell Chongqing clinical Clinical and laboratory data coronavirus disease COVID-19 COVID-19 patient COVID-19 patients Critical cutoff value cytokine cytokine profile Cytokines diabetes Diabetes Mellitus enrolled evaluate Factor Hospital admission ICU ICU admission ICU patient ICU Patients IL-6 independent predictor independent predictors Infection interleukin laboratory data Logistic regression Logistic regression analysis lymphocyte Lymphocyte subset Lymphocyte subsets Lymphocytes lymphopenia Most patients multivariate multivariate logistic regression analysis mutant natural killer no statistical difference No statistical differences non-ICU non-ICU patient non-ICU patients Odds ratio Patient patients patients with COVID-19 peripheral lymphocyte Predictive Predictive value receiver operating characteristic ROC ROC Curve selected sensitivity severe disease severe group severity severity of COVID-19 significantly significantly higher specificity statistical differences subset T cell T cells tested the disease Three Gorge Three Gorges treated university virus infection was used wild-type virus [DOI] 10.1186/s12985-022-01786-2 PMC 바로가기 [Article Type] Article
BNT162b2 Third Booster Dose Significantly Increases the Humoral Response Assessed by Both RBD IgG and Neutralizing Antibodies in Renal Transplant RecipientsBNT162b2 3차 부스터 용량은 신장 이식 수혜자의 RBD IgG 및 중화 항체 모두에 의해 평가된 체액 반응을 상당히 증가시킵니다Article Published on 2022-03-212022-09-11 Journal: Transplant International [Category] MERS, SARS, 진단, 치료기술, [키워드] 95% CI Allograft antibody Antibody Response BNT162b2 BNT162b2 vaccine booster COVID-19 COVID-19 vaccine develop Diabetic diabetic nephropathy Dilution domain dose effective ESRD geometric mean geometric mean titer geometric mean titers GMT GMTs group had no humoral Humoral response IgG Immunosuppression increase independent predictor independent predictors mycophenolic acid negative and positive nephropathy Neutralizing antibodies neutralizing antibody non-responder non-responders of BNT162b2 Patient positive predictor pseudo-virus RBD RBD IgG Receptor-binding domain recipient recipients remained renal Renal transplantation Responder responders response response rate SARS-CoV-2 secondary to seroconverted significant increase stratified systemic systemic AEs the vaccine Transplant Vaccine were recorded [DOI] 10.3389/ti.2022.10239 PMC 바로가기 [Article Type] Article
A sigh of relief: vaccine-associated hypermetabolic lymphadenopathy following the third COVID-19 vaccine dose is short in duration and uncommonly interferes with the interpretation of [ 18 F]FDG PET-CT studies performed in oncologic patients안도의 한숨: 세 번째 COVID-19 백신 접종 후 백신 관련 대사과다 림프절병증은 지속 기간이 짧고 드물게 종양 환자에서 수행된 [ 18 F]FDG PET-CT 연구의 해석을 방해합니다Article Published on 2022-03-012022-09-11 Journal: European Journal of Nuclear Medicine and Molecular [Category] SARS, 치료기술, [키워드] administration age BMI BNT162b2 BNT162b2 vaccine correlation COVID-19 COVID-19 vaccine dose dose administration doses GRADE High-grade Humoral immunity immune response incidence incidence of COVID-19 independent predictor independent predictors interfere Interpretation IQR less Lymphadenopathy median time multivariable logistic regression obese obese patients Older Oncologic imaging Patient patients performed PET-CT reported separation time interval unlikely vaccination vaccine dose were recorded [DOI] 10.1007/s00259-021-05579-7 PMC 바로가기 [Article Type] Article
Prognostic Markers in Hospitalized COVID-19 Patients: The Role of IP-10 and C-Reactive Protein입원한 COVID-19 환자의 예후 마커: IP-10 및 C-반응성 단백질의 역할Observational Study Published on 2022-02-282022-09-10 Journal: Disease Markers [Category] MERS, 바이오마커, 임상, [키워드] Admission Analysis analyzed Asymptomatic AUC baseline baseline characteristics Biomarker C-reactive protein C-reactive protein (CRP characteristic chemokine clinical condition clinical conditions clinical decision clinically cohort study Concentration Course COVID-19 CRP cytokine death discharge disease disease onset disease severity driving enrolled Evolution expected growth factor heterogeneous Hospital stay Hospitalization Hospitalized hospitalized COVID-19 patients identify immunological independent predictor independent predictors intensive care intensive care unit IP-10 Italy Laboratory Laboratory tests majority Manifestations moderate moderate to severe Multivariate analysis outcome pandemic Patient performed predict prospective cohort study responsible Result ROC role SARS-CoV-2 SARS-CoV-2 positive patient sensitivity serum serum concentrations specificity Stratification trajectory worsening [DOI] 10.1155/2022/3528312 PMC 바로가기 [Article Type] Observational Study
Elevated levels of serum CDCP1 in individuals recovering from severe COVID-19 disease심한 covid-19 질병으로부터 회복되는 개인에서 혈청 cdcp1의 높은 수준Research Paper Published on 2022-02-282022-09-10 Journal: Aging (Albany NY) [Category] MERS, 바이오마커, [키워드] Biomarker Biomarkers carbon monoxide CDCP1 correlation correlations COVID-19 difference diffusing diffusing capacity discharge group hospital hospital discharge Hospitalization identify implication independent predictors Indicator individual Inflammatory biomarker inflammatory biomarkers laboratory-confirmed Laboratory-confirmed COVID-19 Level lung abnormalities lung abnormality Lung function median onset of symptom Patient predictor prognostic recovery recruited SARS-CoV-2-infected patient SARS-CoV-2-infected patients serum Severe case severe cases severe COVID-19 disease severe disease severity severity of COVID-19 significant difference significantly lower Spain sputum Sputum sample sputum samples survivor Symptom were measured [DOI] 10.18632/aging.203898 PMC 바로가기 [Article Type] Research Paper