Population-based screening in a municipality after a primary school outbreak of the SARS-CoV-2 Alpha variant, the Netherlands, December 2020-February 2021Article Published on 2022-10-272022-11-16 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] age Alpha Alpha variant Analysis caused children circulation Clinical symptoms confounders epidemiological link individual infected individual infected individuals Laboratory Lineage B.1.1.7 Netherlands not significantly different outbreak PCR Prevent public health measures questionnaire SAR SARS-CoV-2 SARS-CoV-2 variant School Schools secondary attack rate self-reported symptom sequence Sequencing spread to the mean the SARS-CoV-2 Transmission variant virus virus transmission was determined was used whole genome [DOI] 10.1371/journal.pone.0276696 PMC 바로가기
New-onset dermatomyositis following COVID-19: A case reportArticle Published on 2022-10-242022-11-16 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome addition anti-aminoacyl tRNA synthetase (ARS) antibodies anti-synthetase antibodies antibodies antibody association autoantibody Autoimmune Autoimmune disease Autoimmune diseases biochemical analysis Biological Case report caused Chest clinical feature Clinical features complications Computed tomography contributed coronavirus Coronavirus disease 2019 Corticosteroids cough COVID-19 de novo dermatomyositis dermatomyositis. develop diagnosed diagnostic Dyspnea edema elevations enzyme-linked immunosorbent exacerbate Fever highlight Hospitalization IgG ILD immunoblot infected individual Infectious disease Inflammatory interstitial Interstitial lung disease Japan Japanese lower lobe Lungs male manifestation MOST myalgia myopathies myositis Occurrence organ pathological findings Patient polymerase chain positive Prednisolone presenting profile respiratory symptom SARS-CoV-2 skin rash sore throat Swab syndrome tested transaminases treated tRNA weakness [DOI] 10.3389/fimmu.2022.1002329 PMC 바로가기
Comparative effectiveness of neutralising monoclonal antibodies in high risk COVID-19 patients: a Bayesian network meta-analysisArticle Published on 2022-10-202022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), meta-analysis, SARS, 변종, 진단, [키워드] absolute reduction article baseline Bayesian comparable Comparative COVID-19 Effect effective Effectiveness Efficacy Evidence expected generalisability healthcare high risk hospitalisation ICU admission identify individual infected individual infected with SARS-CoV-2 invasive ventilation moderate monoclonal antibody Mortality network Network meta-analysis neutralising outcome Pairwise comparison patient population patients patients treated Placebo predict Rate RCT reaction reduce mortality reducing reduction in relative risk risk reduction serious AE severe COVID-19 statistically significant reduction systematic review therapy treatment effect vaccination variant [DOI] 10.1038/s41598-022-22431-6 PMC 바로가기
Effectiveness of inactivated and Ad5-nCoV COVID-19 vaccines against SARS-CoV-2 Omicron BA. 2 variant infection, severe illness, and deathArticle Published on 2022-10-202022-11-15 Journal: BMC Medicine [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] 1:1 Administering administration all age group all age groups booster dose case-control study conducted Control COVID-19 COVID-19 vaccine COVID-19-related death Critical death deaths diagnosed died dose effective Effectiveness eligible Gender illness onset inactivated Inactivated vaccine individual individuals infected individual Infection Limited omicron outcomes progressed provided SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2-infected individuals selected severe COVID-19 subset sustained vaccination Vaccine vaccine effectiveness variant [DOI] 10.1186/s12916-022-02606-8 PMC 바로가기
Individual-based modeling reveals that the COVID-19 isolation period can be shortened by community vaccinationArticle Published on 2022-10-202022-11-16 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI approach B.1.617.2 baseline BNT162b2 vaccine booster vaccination Community Contact COVID-19 Delta Effect effective vaccine emotional Impact individual infected individual infected individuals Infection Isolation less likelihood mitigate nonpharmaceutical intervention occur outbreak profile Psychological quarantine reduce reveal risk Secondary infection subsequent sustained the patient the SARS-CoV-2 Transmission transmission of SARS-CoV-2 vaccination Vaccine-induced immunity variant Viral load [DOI] 10.1038/s41598-022-21645-y PMC 바로가기
Comparison of the kinetics and magnitude of antibody responses to different SARS-CoV-2 proteins in Sinopharm/BBIBP-CorV vaccinees following the BNT162b2 booster or natural infectionArticle Published on 2022-10-132022-11-15 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 진단, [키워드] ACE2 anti-RBD antibodies antibody Antibody Response BNT162b2 booster Cohort dose Frequency highest IgG antibody immune response implication individual infected individual Infection investigated lowest magnitude natural infection persistence post vaccination Protein receive remained robust S1 and S2 SARS-CoV-2 protein second dose significantly higher Sinopharm subsequent the N protein the RBD the SARS-CoV-2 virus total antibody uninfected vaccinee vaccinees were infected [DOI] 10.1371/journal.pone.0274845 PMC 바로가기
Humoral and cellular immune response over 9 months of mRNA-1273, BNT162b2 and ChAdOx1 vaccination in a University Hospital in SpainArticle Published on 2022-10-072022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 진단, [키워드] antibody BNT162b2 booster vaccinations carried cellular Cellular immune response cellular immunity ChAdOx1 COVID-19 COVID-19 vaccination dose elimination half-life Follow-up healthcare worker Heterologous humoral Immunity individual infected individual inoculated mRNA-1273 naïve Naturally participant preserved Prospective Study receiving reported robust SARS-CoV-2 spike second dose single dose Spain T cell uninfected university vaccination Vaccine Validity [DOI] 10.1038/s41598-022-19537-2 PMC 바로가기
Blood Endothelial-Cell Extracellular Vesicles as Potential Biomarkers for the Selection of Plasma in COVID-19 Convalescent Plasma TherapyArticle Published on 2022-10-042022-11-15 Journal: Cells [Category] 바이오마커, [키워드] Activation age anti-SARS-CoV-2 antibody Biomarkers Blood blood endothelium cardiovascular disease caused CCP CCP therapy Characteristics characterized clinical symptom Concentration consequence convalescent plasma Convalescent plasma therapy coronavirus disease COVID-19 death Donor downregulation Endothelial cell Endothelial dysfunction Endothelium evidenced excessive inflammation expected extracellular vesicle Extracellular vesicles extracellular vesicles. hospital ICAM1 identify individual infected individual inflammatory storm massive secretion mechanism mild symptoms mitochondrial dysfunction multi-organ failure onset of symptom overexpression parameter Peripheral blood plasma Potential pro-inflammatory pro-inflammatory cytokine progression promoted reflected selected Selection severity subset Symptoms the disease therapy vaccination Vascular endothelium vascular inflammation vessel was increased [DOI] 10.3390/cells11193122 PMC 바로가기
Biophysical and Biochemical Characterization of the Receptor Binding Domain of SARS-CoV-2 VariantsArticle Published on 2022-10-012022-11-16 Journal: The protein journal [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2 adopted affinity antibody biochemical characterization Degradation help host cell receptor host receptor immune response immunological IMPROVE increase in infected individual interact Intervention medical intervention mutant Mutation mutations natural selection neutralizing antibody parental protease Rapid RBD receptor Receptor binding domain responses SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 variant sensitivity the RBD thermal stability Transmissibility understanding variant variants variants of concern [DOI] 10.1007/s10930-022-10073-6 PMC 바로가기
Genetic sequencing detected the SARS-CoV-2 delta variant in wastewater a month prior to the first COVID-19 case in Ahmedabad (India)Short communication Published on 2022-10-012022-10-05 Journal: Environmental pollution (Barking, Essex : 1987) [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Analysis analyzed B.1.617.2 circulating circulating variant clinical sample clinically COVID-19 COVID-19 case COVID-19 cases D614G Deletion delta variant detect detection First wave Frequency Genetic genomic Gujarat Health identify India infected individual L452R Lineage majority Mutation P681R SARS-CoV-2 SARS-CoV-2 variant second wave Sequencing Spike protein Surveillance symptomatic patient T19R T478K the SARS-CoV-2 the SARS-CoV-2 genome the spike protein variant variants of concern VOCs wastewater surveillance [DOI] 10.1016/j.envpol.2022.119757 [Article Type] Short communication