Myoglobin and C-reactive protein are efficient and reliable early predictors of COVID-19 associated mortality미오글로빈 및 C 반응성 단백질은 COVID-19 관련 사망률의 효율적이고 신뢰할 수 있는 조기 예측 인자입니다Article Published on 2021-03-162022-09-01 Journal: Scientific Reports [Category] SARS, 바이오마커, 임상, 진단, [키워드] age average Biomarkers Blood BNP C-reactive protein cardiac injury collected Comorbidities Comorbidity comprehensive analysis Consensus correlated COVID-19 COVID-19 disease COVID-19 severity CRE CRP D-dimer Deceased demise determine diagnosed with COVID-19 dysfunction elevated full recovery Health care hepatic impairment Huoshenshan Hospital indicated initial symptoms Laboratory lack LDH Medical research Mortality multiple organ failure Myoglobin onset of symptom Organ failure Patient patients predict predictor renal renal damage retrospective cohort study risk factor Risk factors SARS-CoV-2 severely ill patient significantly Signs and symptoms troponin Troponin-I Wuhan [DOI] 10.1038/s41598-021-85426-9 PMC 바로가기 [Article Type] Article
Chest CT Imaging Features of Typical Covert COVID-19 Cases일반적인 은밀한 COVID-19 사례의 흉부 CT 영상 특징Research Paper Published on 2021-03-152022-09-12 Journal: International Journal of Medical Sciences [Category] MERS, 진단, [키워드] affected analyzed Characteristics Chest CT clinical consolidation covert coronavirus infections. COVID-19 CT CT finding CT findings demonstrated disease course enrolled GGO ground glass opacities imaging initial initial symptom initial symptoms lobe lobes lung male material median negative RT-PCR Patient positive positive RT-PCR progression radiological Retrospective study RT-PCR SARS-CoV-2 severity significant difference Swab test Throat Typical with COVID-19 [DOI] 10.7150/ijms.48614 PMC 바로가기 [Article Type] Research Paper
Humoral response to COVID-19 infection in immunosuppressed patients with inflammatory bowel disease염증성 장질환이 있는 면역억제 환자의 코로나19 감염에 대한 체액 반응Case Reports Published on 2021-03-012022-09-11 Journal: European journal of gastroenterology & hepatology [Category] SARS, 바이오마커, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission advanced age Anosmia antibody Antibody testing cardiovascular diseases clinical manifestation Comorbidity coronavirus Course COVID-19 COVID-19 infection described determined by diabetes diarrhea disease severity dysgeusia hospital Humoral response hypertension IBD ICU immune response immunosuppressed patient Immunosuppression immunosuppressive Immunosuppressive medication immunosuppressive therapy Immunosuppressive treatment Indicator Infection Inflammatory bowel disease initial symptoms management older patient older patients Patient patients patients with COVID-19 PCR Pyrexia respiratory restart SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antibody testing severe acute respiratory syndrome Coronavirus symptoms of COVID-19 tested therapy virus-specific antibodies [DOI] 10.1097/MEG.0000000000002094 PMC 바로가기 [Article Type] Case Reports
Sex Differences in the Incidence and Risk Factors of Myocardial Injury in COVID-19 Patients: A Retrospective Cohort StudyPhysiology Published on 2021-02-162022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] 95% CI 95% confidence interval adverse events age association BNP both sexes can be used Chronic kidney disease Clinical management Clinical outcome coagulation disorder collected Comorbidity Coronary artery disease correlation COVID-19 COVID-19 patient D-dimer demographic characteristics difference enrolled Factor female Female patients greater Hospitalized Huoshenshan Hospital hypertension identify IMPROVE incidence independent risk factor Inflammation initial symptoms Laboratory test lack leucocyte Logistic regression analysis male mechanisms men myocardial injury novel coronavirus disease Patient Retrospective study risk-factors Sex Sex difference sex differences women [DOI] 10.3389/fphys.2021.632123 PMC 바로가기 [Article Type] Physiology
A quadruple blinded placebo controlled randomised trial to evaluate the effectiveness of an Iodine complex for patients with mild to moderate COVID-19 in Pakistan (I-COVID-PK): A structured summary of a study protocol for a randomised controlled trial파키스탄에서 경증에서 중등도의 COVID-19 환자에 대한 요오드 복합체의 효과를 평가하기 위한 4중 맹검 위약 대조 무작위 시험(I-COVID-PK): 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-02-102022-09-10 Journal: Trials [Category] MERS, 임상, [키워드] 30-Day mortality Admission age alleviation alleviation of symptom approved Arm ARMS baseline blinded Blinding calculated Care care providers Chest chest scan Chronic illness clinic clinical Clinical improvement Clinical management co-morbidities co-morbidity comparator complex coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 adult patient COVID-19 adult patients Disinfection dissemination doctor Effectiveness Efficacy element enrolled evaluate excluded four group four groups Gender groups HRCT Infection information initial initial symptom initial symptoms Intention investigator investigators Iodine IRB lung involvement management guidelines Mild mild to moderate mild to moderate disease Moderate COVID-19 moderate disease morbidities National Health Service National Health Services non-pregnant females number objective outcome Pakistan participant Participants Patient patients PCR Placebo placebo-controlled Polymer positive Primary outcomes protocol radiological radiological improvement randomised randomised controlled trial Randomised trial randomization Randomized receiving recruited recruitment Registered remained reported resolved RT-PCR Sample size SARS-CoV-2 RT-PCR secondary outcome severity severity of symptom shown Standard standard care status Study protocol supplementary material Symptom symptomatic syrup the patient time Trial Version Viral viral clearance website [DOI] 10.1186/s13063-021-05081-3 PMC 바로가기 [Article Type] Letter
Increased levels of plasma cytokines and correlations to organ failure and 30-day mortality in critically ill Covid-19 patients중환자 코로나19 환자의 혈장 사이토카인 수치 증가 및 장기 부전 및 30일 사망률과의 상관관계Article Published on 2021-02-012022-09-11 Journal: Cytokine [Category] SARS, 바이오마커, [키워드] 30-Day mortality abdominal surgery Acute kidney injury Admission Biomarkers Care caused Cohort controls Corona virus correlated correlation COVID-19 Critically ill critically ill COVID-19 patients cytokine cytokine expression cytokine response Cytokine storm Cytokine storm syndrome Cytokines death demonstrated expression IL-17A IL-1ra IL-4 IL-6 IL-8 increase increase in Increased induce Infection Inflammation inflammatory markers inflammatory mediator Inflammatory mediators Inflammatory response Informed consent initial symptoms intensive care IP-10 kidney Kidney injury MCP-1 median mediators moderate Mortality organ damage Organ failure Patient patients PCR-confirmed PCR-confirmed COVID-19 plasma Plasma cytokine plasma sample quantified Respiratory failure SARS CoV SARS CoV-2 SOFA score the strongest was obtained [DOI] 10.1016/j.cyto.2020.155389 PMC 바로가기 [Article Type] Article
Neurological features and outcome in COVID-19: dementia can predict severe diseaseObservational Study Published on 2021-02-012022-10-05 Journal: Journal of Neurovirology [Category] 임상, [키워드] age Ageusia Altered mental status Anosmia/ageusia appear Comorbidities conducted cough Course COVID-19 COVID-19 pandemic Dementia diagnosis of COVID-19 Dizziness Dyspnea enrolled feature Fever headache history Imam initial initial symptom initial symptoms intensive care males Mortality mortality rate nervous nervous system neurological Neurological complication Neurological complications Neurological symptoms NEUROLOGY Odds ratio outcome Patient predict SARS-CoV-2 severe COVID-19 severe COVID-19 disease severe disease Sex Symptom the disease the patient [DOI] 10.1007/s13365-020-00918-0 PMC 바로가기 [Article Type] Observational Study
Modeling the initial phase of SARS-CoV-2 deposition in the respiratory tract mimicked by the 11 C radionuclideResearch Article Published on 2021-01-142022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] alveolar ambient clinical observation comparable COVID-19 event experiment fraction Infection initial initial symptoms knowledge lung Microparticle modeling provide required respiratory tract SARS-CoV-2 tested viral particle virus [DOI] 10.1371/journal.pone.0245019 PMC 바로가기 [Article Type] Research Article
Effects of Tocilizumab in COVID-19 patients: a cohort studyCOVID-19 환자에서 Tocilizumab의 효과: 코호트 연구Observational Study Published on 2020-12-222022-09-01 Journal: BMC Infectious Diseases [Category] MERS, SARS, 임상, 진단, [키워드] Administered black Clinical improvement cohort study Complication conducted coronavirus COVID-19 CRP cytokine Cytokine release syndrome Cytokine storm demonstrated died discharged dose early administration early treatment Effect evaluated help Hispanic hospital Hospital admission Hospitalized Hyperinflammatory Hyperinflammatory response IL-6 IL-6 receptor Infectious complications initial initial symptom initial symptoms intravenous tocilizumab lack male median median age mitigate Most patient Most patients observational study occurred PaO Patient progressive respiratory failure randomized controlled study receiving reduction in remained Respiratory failure Result retrospective SARS-CoV-2 slight increase subsequent supplementary material sustained Therapies Tocilizumab [DOI] 10.1186/s12879-020-05701-4 PMC 바로가기 [Article Type] Observational Study
Long-Term Existence of SARS-CoV-2 in COVID-19 Patients: Host Immunity, Viral Virulence, and TransmissibilityCOVID-19 환자에서 SARS-CoV-2의 장기 존재: 숙주 면역, 바이러스 독성 및 전염성Article Published on 2020-12-012022-09-11 Journal: Virologica Sinica [Category] MERS, SARS, 변종, 진단, 치료기술, [키워드] antibody CD4 CD8 Cell cell supernatant cell supernatants Clinical characteristics clinically coding regions Cohort collected COVID-19 COVID-19 patient cured Cytopathic effect demographic demographic data detectable Existence favor Genome sequencing IFN-γ IgG initial symptom initial symptoms inoculated interferon gamma long-term lymphocyte Lymphocyte functionality Lymphocytes median median age Mild Nasopharyngeal swab nasopharyngeal swab sample Nasopharyngeal swab samples neutralisation Neutralization antibody Neutralizing activity Neutralizing antibodies neutralizing antibody NK cell NK cells nucleic acid test passages pathogenicity Patient patients peripheral positive positively correlated SARS-CoV-2 SARS-CoV-2 clearance SARS-COV-2 infection SARS-CoV-2 nucleic acid SARS-CoV-2 virus Sequencing Spike protein synonymous variant Vero E6 Vero E6 cell VERO E6 cells Viral viral clearance Viral load viral pathogenicity [DOI] 10.1007/s12250-020-00308-0 PMC 바로가기 [Article Type] Article