Interpatient variability in the pharmacokinetics of remdesivir and its main metabolite GS-441524 in treated COVID-19 subjectsArticle Published on 2022-09-302022-11-15 Journal: Journal of Antimicrobial Chemotherapy [Category] SARS, 치료제, [키워드] affected age antiviral drug approved association baseline blood sample BMI calculated collected comparison Concentration COVID-19 COVID-19 patients COVID-19 severity Efficacy enrolled evaluated glomerular filtration rate GS-441524 ICU identify independent predictor Inpatient Inpatients inter-individual Liver function Logistic regression metabolite Multiple linear regression Multiple regression analysis parameter Patient pharmacokinetic plasma Remdesivir renal renal function required Research SARS-CoV-2 SARS-CoV-2 infections Sex Standard-dose statistical subject transaminase treated Treatment Variability variables were assessed were measured were used [DOI] 10.1093/jac/dkac234 PMC 바로가기
Model-Based Analysis of SARS-CoV-2 Infections, Hospitalization and Outcome in Germany, the Federal States and DistrictsArticle Published on 2022-09-242022-11-16 Journal: Viruses [Category] SARS, 변종, [키워드] affected age analyses applied B.1.1.7 Care coronavirus disease Coronavirus disease 2019 (COVID-19) covariate COVID-19 COVID-19 patient Critical develop discrepancy distribution District Effect epidemiological fatality Germany Government Health health care systems hospital ICU ICU patient Infection Inpatients Intensive intensive care intensive care unit Intervention limit Local management mathematical mathematical model mechanical ventilation modeling National Non-pharmaceutical interventions outcome pandemic patient age performed positive recorded reduce regions reported resources SARS-CoV-2 SARS-COV-2 infection severity Sex Spread state Testing strategy Variability variant variant of concern (VOC) VoC [DOI] 10.3390/v14102114 PMC 바로가기
Increasing anti-S antibody testing: a quality improvement initiative with evolving COVID-19 guidelinesArticle Published on 2022-09-012022-11-16 Journal: BMJ open quality [Category] 변종, [키워드] added Admission analysed anti-S anti-S antibody approach baseline Clinical practice COVID-19 COVID-19 guideline criteria eligible Final Guidance highlighting IMPROVE increase in Increasing Inpatients Intervention introduced Local management guideline monoclonal antibody Mortality neutralising observé outcomes Patient patients with COVID-19 Quality Quality improvement Quality measurement reduce reduction in Research seronegative patient symptomatic variants [DOI] 10.1136/bmjoq-2022-001886 PMC 바로가기
Changing Patterns of Bloodstream Infections in the Community and Acute Care Across 2 Coronavirus Disease 2019 Epidemic Waves: A Retrospective Analysis Using Data Linkage2개의 코로나바이러스 질병 2019 전염병에 따른 지역사회 및 급성 치료의 혈류 감염 패턴 변화: 데이터 연결을 사용한 후향적 분석Article Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Alpha variant analyzed antimicrobial resistance Bacteremia Blood bloodstream infection Bloodstream infections BSI case mix change changes in Changing Community complex coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Culture cultures driving Epidemic Escherichia coli examined Factor First wave healthcare healthcare-associated infection. hospital Hospital stay impacted incidence Infection Inpatients intensive care linkage lockdown London Mortality non-COVID-19 patient Non-COVID-19 patients pandemic Patient pattern peaked peaking presenting remained reported sampling SARS-CoV-2 second wave severe acute respiratory syndrome Coronavirus significant increase Surveillance variants [DOI] 10.1093/cid/ciab869 PMC 바로가기 [Article Type] Article
Cardiopulmonary Imaging Utilization and Findings among Hospitalized COVID-19 Patients in Latin America: (From “RIMAC: Registry IMAging Cardiopulmonary among Hospitalized COVID-19 Patients in LATAM”)Observational Study Published on 2022-08-012022-10-04 Journal: Global Heart [Category] SARS, 임상, [키워드] Admission America association Cardiopulmonary Cardiopulmonary Images carried Chest CT Comorbidities Comorbidity complications conducted COVID-19 COVID-19 hospitalization diabetes Diagnosis discharge Evolution finding ground glass heart highest Hospitalization hospitalized patient hypertension ICU imaging In-hospital death in-hospital mortality information Inpatients interstitial lack LATAM Latin Latin America lung magnetic resonance imaging males median age Myocardial infarction nine pandemic performed predominant prevalent Prognosis Region regions registry RIMAC SARS-CoV-2 severity South America syndrome the SARS-CoV-2 Thromboembolism utilization X-ray [DOI] 10.5334/gh.1134 PMC 바로가기 [Article Type] Observational Study
Evaluation of hematological parameters and inflammatory markers in children with COVID-19COVID-19 소아의 혈액학적 매개변수 및 염증 표지자 평가Article Published on 2022-08-012022-09-11 Journal: Irish Journal of Medical Science [Category] 바이오마커, [키워드] 95% CI abnormality applied best blood cell C-reactive protein C-reactive protein (CRP can be used children children with COVID-19 COVID-19 CRP cutoff value D-dimer determine distribution Effect evaluate hematological hematological parameter hematological parameters hemoglobin Hospitalization identify independent predictor independent predictors Inflammatory biomarker inflammatory biomarkers Inflammatory marker inflammatory markers Inpatient Inpatients lymphocyte lymphopenia mean platelet volume monocyte multivariate logistic regression neutrophil Outpatient outpatients Patient Platelet platelet counts procalcitonin procalcitonin level Red cell retrospective risk factor Risk factors ROC analysis separated significantly higher significantly lower single-center study study population two groups Volume was performed WBC White blood cell [DOI] 10.1007/s11845-021-02762-5 PMC 바로가기 [Article Type] Article
Control of an outbreak of COVID-19 at a tertiary hospital in TaiwanResearch article Published on 2022-08-012022-10-05 Journal: Journal of microbiology, immunology, and infection [Category] 치료기술, [키워드] Admission Cluster conducted Control Coronavirus disease 2019 COVID-1 COVID-19 COVID-19 outbreak COVID-19 testing evaluate expired exposure time HCW HCWs healthcare worker hidden hospital Hospital admission Hospitalized hosts index case Infection infection control Inpatients measure Memorial New Taipei City Nurse outbreak Patient patients PCR positive Result risk factor susceptible symptomatic patient Taiwan Transmission was performed [DOI] 10.1016/j.jmii.2022.08.001 [Article Type] Research article
SARS-CoV-2 Seroprevalence among Healthcare Workers after the First and Second Pandemic Waves1차 및 2차 대유행 이후 의료 종사자 사이의 SARS-CoV-2 혈청 유병률Article Published on 2022-07-142022-09-12 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] anti-SARS-CoV-2 antibody antibodies Belgium Blood Charleroi confirmed COVID-19 case Contact COVID-19 criteria cross-sectional diagnostic DiaSorin distribution First wave General population HCW HCWs healthcare healthcare worker Healthcare workers hospital IgG test Inpatients LIAISON pandemic pandemic waves Patient patients performed positive predominant Prevalence questionnaire recruitment repeated risk risk factor S1/S2 SARS-CoV-2 second second wave Seroconversion serological test Serological testing Seroprevalence significantly higher single-center study participant Symptom treated Wave worker [DOI] 10.3390/v14071535 PMC 바로가기 [Article Type] Article
The Impact of SARS-CoV-2 Pandemic on Patients with Malignant Melanoma at a Romanian Academic Center: A Four-Year Retrospective Analysis루마니아 학술 센터의 악성 흑색종 환자에 대한 SARS-CoV-2 유행병의 영향: 4년 후향적 분석Article Published on 2022-07-122022-09-11 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), SARS, 치료기술, [키워드] age Analysis Anemia appointments average can not Cancer cancer patient Cancer patients Care comprehensive evaluation COVID-19 COVID-19 disease COVID-19 pandemic database detect determine diagnosed Diagnosis Disease progression Epidemiology Final hospital Impact inclusion criteria increased risk Inpatients limitation lockdown malignant malignant disease malignant diseases Malignant melanoma management Medical care Melanoma outcomes Outpatient outpatients outpatients and inpatient P -value pandemic Patient plastic surgery prevalent proportion required responsible Retrospective analysis risk factor Risk factors Romania SARS-CoV-2 screened severe COVID-19 disease significantly significantly lower skin cancer statistically statistically significant difference study period Treatment [DOI] 10.3390/ijerph19148499 PMC 바로가기 [Article Type] Article
Respiratory viruses in rural Zambia before and during the COVID-19 pandemicCOVID-19 전염병 이전과 동안 잠비아 시골의 호흡기 바이러스Article Published on 2022-07-012022-09-11 Journal: Tropical medicine & international health : TM & IH [Category] 치료기술, [키워드] Admission Admissions Africa Analysis changed children circulation clinics collected conducted COVID-19 COVID-19 pandemic enterovirus Epidemiology evaluate evaluated Influenza Influenza virus influenza viruses Inpatients Macha métapneumovirus Nasopharyngeal samples Outpatient outpatients outpatients and inpatient pandemic parainfluenza parainfluenza virus participant pathogen Pathogens Prevalence Public health intervention Public health interventions recruited respiratory Respiratory illness respiratory pathogen Respiratory pathogens respiratory symptom respiratory symptoms respiratory syncytial virus respiratory virus respiratory viruses rhinovirus SARS-CoV-2 significantly sub-Saharan Africa Surveillance tested virus Year [DOI] 10.1111/tmi.13781 PMC 바로가기 [Article Type] Article