COVID-19 mRNA vaccines drive differential Fc-functional profiles in pregnant, lactating, and non-pregnant womenArticle Published on 2022-04-042022-11-01 Journal: Science Translational Medicine [Category] COVID-19, MERS, SARS, [키워드] antibody BNT162b2 vaccine breastmilk change changes changes in comparable contribute controls COVID-19 COVID-19 mRNA vaccine Critical develop fetal function growth humoral immune response immune system Immunity immunological immunological change indicate induce Infection Inflammatory lactating lactating women lactation less Local mother mRNA-1273 normalized occur pathogen physiological Pregnancy pregnant pregnant women profile promote PROTECT receptor second dose severe coronavirus disease susceptibility timeline Tolerance vaccination vaccine dose vaccine response women [DOI] 10.1126/scitranslmed.abi8631 PMC 바로가기 [Article Type] Article
COVID-19 vaccines: Considering sex differences in efficacy and safetyReview article Published on 2022-04-012022-10-05 Journal: Contemporary clinical trials [Category] COVID19(2023년), SARS, 임상, [키워드] Administered approval clinical trial COVID-19 COVID-19 pandemic COVID-19 vaccine Efficacy and safety exclusion female General population lactating male peer-reviewed phase populations Precision Pregnancy pregnant question reaction Regulatory SARS-CoV-2 vaccine Sex Sex difference sex differences shown stimulate Vaccine vaccine trial Vaccines [DOI] 10.1016/j.cct.2022.106700 [Article Type] Review article
Titres and neutralising capacity of SARS-CoV-2-specific antibodies in human milk: a systematic review모유 내 SARS-CoV-2 특이 항체의 역가 및 중화 능력: 체계적인 검토Article Published on 2022-03-012022-09-12 Journal: Archives of disease in childhood. Fetal and neonat [Category] MERS, SARS, 진단, [키워드] anti-SARS-CoV-2 antibody articles Asymptomatic asymptomatic infection CINAHL CNKI COVID-19 COVID-19 infection current database demonstrated disease Evidence Google Scholar Holder Human human milk IgA IgG IgM illness immunoglobulin A in vitro individual individuals with COVID-19 Infection lactating Mild milk neonatology neutralise neutralising Neutralising Antibodies neutralising antibody outcome performed Presence preserved provided SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 virus SARS-CoV-2-specific antibody selected severe disease severity Study design systematic review tested Virology WHO with COVID-19 [DOI] 10.1136/archdischild-2021-322156 PMC 바로가기 [Article Type] Article
High-dose ivermectin for early treatment of COVID-19 (COVER study): a randomised, double-blind, multicentre, phase II, dose-finding, proof-of-concept clinical trialCOVID-19의 조기 치료를 위한 고용량 이버멕틴(COVER 연구): 무작위, 이중 맹검, 다기관, 2상, 용량 찾기, 개념 증명 임상 시험Clinical Trial Published on 2022-02-012022-09-11 Journal: International journal of antimicrobial agents [Category] COVID19(2023년), MERS, SARS, 신약개발, 임상, 진단, 치료법, 치료제, [키워드] Adverse drug reaction Adverse drug reactions Antiviral antiviral activity assigned calculated Chloroquine phosphate CNS Concentration COVID-19 criteria Day demonstrated diagnosed dialysis double-blind early treatment Efficacy exclusion criteria High-dose Hydroxychloroquine hydroxychloroquine treatment in viral in vitro individual Ivermectin lactating log multicentre no significant difference no significant differences outcome participant Participants Placebo pregnant Primary outcomes Prognosis proof-of-concept clinical trial randomised randomised controlled trial reduce reducing Registered Safe safety analysis SARS-CoV-2 SARS-COV-2 infection significant differences Treatment Viral Viral load viral load reduction Warfarin [DOI] 10.1016/j.ijantimicag.2021.106516 PMC 바로가기 [Article Type] Clinical Trial
An update on COVID-19 and pregnancyArticle Published on 2022-02-012022-11-16 Journal: American journal of obstetrics and gynecology [Category] COVID19(2023년), SARS, 치료기술, [키워드] accumulating addition Administered adverse effect Affect age alteration angiotensin-converting enzyme 2 appear Cell center comparable Control COVID-19 COVID-19 vaccine death determine Effect Evidence extracorporeal membrane oxygenation fetal fetal death fetus Health Healthcare system improvement incidence increase information intensive care invasive ventilation lack lactating Maternal death Newborn nonpregnant outcome outcomes pandemic perinatal infection Placenta Pneumonia Pregnancy pregnant Preterm birth prevention reported reproductive risk factor SARS-CoV-2 SARS-CoV-2 entry SARS-COV-2 infection severe COVID-19 disease severe disease severity of COVID-19 Stillbirth Support Surveillance susceptibility the United State the vaccine transmembrane serine protease Transmission transmission of SARS-CoV-2 vertical transmission Viremia women [DOI] 10.1016/j.ajog.2021.08.054 PMC 바로가기
Association of Human Milk Antibody Induction, Persistence, and Neutralizing Capacity With SARS-CoV-2 Infection vs mRNA VaccinationArticle Published on 2022-02-012022-11-15 Journal: JAMA Pediatrics [Category] COVID19(2023년), SARS, 진단, [키워드] age anti-SARS-CoV-2 antibody Antibody Response BNT162b2 Capacity Cohort cohort study collected Concentration convenience COVID-19 infection COVID-19 vaccine diagnosed Diagnosis domain exhibited first dose fraction functional Human human milk IgA IgA response IgG IgG antibody IgG response individuals induction Infant Infection lactating live SARS-CoV-2 median Messenger RNA microneutralization milk mRNA mRNA vaccination mRNA-1273 neutralization activity outcome parent parental parents participant polymerase chain prevaccination recruited robust SARS-CoV-2 second dose the vaccine vaccination Vaccine vaccine dose virus while [DOI] 10.1001/jamapediatrics.2021.4897 PMC 바로가기
Neutralizing Activity and SARS-CoV-2 Vaccine mRNA Persistence in Serum and Breastmilk After BNT162b2 Vaccination in Lactating WomenImmunology Published on 2022-01-112022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, [키워드] activity antibody antibody isotype BNT162 vaccine BNT162b2 BNT162b2 vaccine Breast feeding breast milk expression breastmilk conducted COVID-19 COVID-19 serological testing detect detectable dose ELISA evaluated Evidence functional healthcare worker IgA IgG IgG1 IgM IgM isotype increase in Infants information IQR isotype lactating majority median age mother mRNA mRNA level mRNA vaccination mRNA vaccine neutralising antibody Neutralizing Neutralizing antibodies neutralizing antibody notable of BNT162b2 PCR persistence prospective cohort study provide RBD-specific IgG1 recruited Result SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 neutralizing antibodies SARS-CoV-2 spike SARS-CoV-2 vaccine SARS-CoV-2-specific antibody serum serum sample significant increase transfer Transient vaccination Vaccine vaccine dose vaccine doses [DOI] 10.3389/fimmu.2021.783975 PMC 바로가기 [Article Type] Immunology
Maternal dietary diversity during lactation and associated factors in Palghar district, Maharashtra, IndiaResearch Article Published on 2021-12-292022-10-28 Journal: PLoS ONE [Category] Coronavirus, SARS, [키워드] Analysis applied benefit binary information children Community counseling Critical deficiencies defined dietary Diversity driven by early phase Factor food food group food groups group Health identify India indicate Intervention lactating lactating women lactation Maternal minimum mother much lower pandemic Pregnancy Prevalence Primary outcome recall risk women [DOI] 10.1371/journal.pone.0261700 PMC 바로가기 [Article Type] Research Article
COVID-19 Vaccine Acceptance of Pregnant and Lactating Women (PLW) in Czechia: An Analytical Cross-Sectional StudyArticle Published on 2021-12-192022-10-30 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] acceptance benefit Breastfeeding carried Characteristics children COVID-19 COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines cross-sectional Czech Republic Decision making demographic characteristics determinant Effectiveness Efficacy employment evaluate Evidence exclusion expected finding Government Health promotion healthcare professionals inactivated indicated Infection initial Intervention lactating lactating women media morbidity and mortality mRNA-based vaccines Obstetric participant Participants platform population subset positive predictor predictors Pregnancy pregnant pregnant women promoter questionnaire receive recommendation Risk assessment significant difference South susceptibility the vaccine trials university utilised vaccination Vaccine Vaccines viral vector-based virus [DOI] 10.3390/ijerph182413373 PMC 바로가기 [Article Type] Article
COVID-19 vaccination in pregnant and lactating women: a systematic review임산부와 수유부의 코로나19 예방접종: 체계적인 검토Article Published on 2021-12-012022-09-12 Journal: Expert review of vaccines [Category] MERS, 진단, [키워드] absence adverse effect anti-SARS-CoV-2 Area Breastfeeding breastmilk COVID-19 COVID-19 pandemic COVID-19 vaccination COVID-19 vaccine Efficacy effort evaluate Evidence excluded expert General population Google Scholar group Humoral immunity Immunoglobulin Infant lactating lactating women lactation Newborn not differ Placenta populations Pregnancy pregnant pregnant women prophylactic strategy Research Result searched subject systematic review transferred vaccinate vaccination Vaccine Vaccines [DOI] 10.1080/14760584.2021.1986390 PMC 바로가기 [Article Type] Article