Evaluation of Host Protein Biomarkers by ELISA From Whole Lysed Peripheral Blood for Development of Diagnostic Tests for Active Tuberculosis활동성 결핵 진단 테스트 개발을 위한 전 용해 말초 혈액에서 ELISA에 의한 숙주 단백질 바이오마커 평가Article Published on 2022-05-202022-09-11 Journal: Frontiers in Immunology [Category] 바이오마커, [키워드] analyses assay associative barrier Biomarker Biomarkers blood sample CALCOCO2 capture cause of death caused CD274 CD52 collected combinations complex conducted confirmatory tests consequence Control correlation country COVID-19 pandemic death defined development diagnosing Diagnosis diagnostic diagnostic test differentially expressed disease Diversity downregulated ELISA ENhance eradication evaluate expression GBP1 group groups Health Health crisis IFIT3 IFITM3 improvement Improvements incidence India individuals infected individuals Infection Infectious disease information investigated Key priorities key priority Laboratory Lateral flow device lysed negative controls nine Patient peripheral profile Protein protein expression Protein target protein targets qPCR Rapid reducing required ROC SAMD9L significantly SNX10 Stratification Test the WHO Tuberculosis validation study WHO World Health Organisation [DOI] 10.3389/fimmu.2022.854327 PMC 바로가기 [Article Type] Article
Inactivation and Recovery of High Quality RNA From Positive SARS-CoV-2 Rapid Antigen Tests Suitable for Whole Virus Genome Sequencing전체 바이러스 게놈 시퀀싱에 적합한 양성 SARS-CoV-2 신속 항원 테스트에서 고품질 RNA의 비활성화 및 회수Article Published on 2022-05-032022-09-11 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료법, [키워드] aligned Antigen antigen testing applied B.1.1.7 can be used circulating variant circulating variants Community Concentration conserved coronavirus 2 demonstrated detect diagnostic diagnostic protocol diagnostic test diagnostic tests each time-point epidemiological Epidemiology Genome genomic sequence identify imperative inactivated Infection lateral flow Lateral flow device Lineage Lineage B.1.1.7 lysed lysis management Omicron variant outbreak positive positive result protocol public health qPCR Quality Rapid Rapid antigen diagnostic test replicating virus respiratory risk Risk management RNA RNA extraction RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 variant SARS-CoV-2 viral sequence Sequencing Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spread stability storage strain Suspension Template Test tested utility Variation viral nucleocapsid protein viral particle Viral particles Viral RNA virus virus genome was used were used whole virus genome sequencing. [DOI] 10.3389/fpubh.2022.863862 PMC 바로가기 [Article Type] Article
SARS-CoV-2 rapid antigen tests provide benefits for epidemic control – observations from Austrian schoolsSARS-CoV-2 급속 항원 검사는 전염병 통제에 이점을 제공합니다 - 오스트리아 학교의 관찰Article Published on 2022-05-012022-09-11 Journal: Journal of clinical epidemiology [Category] COVID19(2023년), SARS, 치료기술, [키워드] Antigen antigen tests benefit Breakthrough infection breakthrough infections children Cohort conducted COVID-19 COVID-19 pandemic Delta detect detectable diagnose diagnostic diagnostic test effective Efficacy Epidemic Evidence false-positive rate information Large-scale testing Lateral Lateral flow device Live virus logistics observation PCR test PCR tests powerful tool Protein Public public health Rapid rapid antigen test Rapid antigen tests Repeat Repeat testing Reproduction number respiratory tract SARS-CoV-2 School Schools spring suppress tested the disease viral genomes Viral load viral loads virus genome virus particles while [DOI] 10.1016/j.jclinepi.2022.01.002 PMC 바로가기 [Article Type] Article
Outcomes of SARS-CoV-2 omicron infection in residents of long-term care facilities in England (VIVALDI): a prospective, cohort studyArticle Published on 2022-05-012022-11-16 Journal: The Lancet. Healthy longevity [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI age Alpha Analysis appear B.1.1.529 booster vaccination Care cohort study Course Coverage datasets death Department diagnosed disease severity eligible England excluded finding for inclusion hazard ratio Hospital admission indicated Infection investigated IQR Lateral flow device male median age MONITOR Mortality National National Health Service natural immunity NHS Observed Omicron variant outcome participant PCR Population positive positive PCR prospective cohort study PROTECT public health reduced reduction in resident risk risk of death SARS-CoV-2 SARS-CoV-2 test Sequencing severe disease severity Sex study period subset Surveillance tested unlikely Vaccine variant variants [DOI] 10.1016/S2666-7568(22)00093-9 PMC 바로가기
IgG antibody production and persistence to 6 months following SARS-CoV-2 vaccination: A Northern Ireland observational studySARS-CoV-2 백신 접종 후 6개월까지 IgG 항체 생성 및 지속성: 북아일랜드 관찰 연구Observational Study Published on 2022-04-202022-09-11 Journal: Vaccine [Category] COVID19(2023년), MERS, SARS, 임상, 진단, 치료기술, [키워드] Adenovirus Adenovirus vector-based vaccine Anti-spike antibody Antibody Response ChAdOx1 clinically collected COVID-19 COVID-19 vaccination detectable dose evaluate first vaccination FIVE IgG antibody IgG response IgG responses individual Ireland Lateral flow device majority Oxford-AstraZeneca Oxford-AstraZeneca ChAdOx1 participant persistence plasma samples pre-vaccination Protein receive rising Sample SARS-CoV-2 second dose significantly higher Spike protein timepoint timepoints Vaccine vaccine dose [DOI] 10.1016/j.vaccine.2022.02.087 PMC 바로가기 [Article Type] Observational Study
Feasibility and acceptability of daily testing at school as an alternative to self-isolation following close contact with a confirmed case of COVID-19: a qualitative analysisRandomized Controlled Trial Published on 2022-04-132022-10-05 Journal: BMC Public Health [Category] COVID19(2023년), SARS, 임상, [키워드] adopted analysed Analysis approach behavioural close contact comparable conducted Contact COVID-19 Critical Daily DCT Device Factor feasible Flow Guidance implementation IMPROVE in both groups Interpretation interview Lateral Lateral flow device LFD negative test parent participant Participants Perspective positive Qualitative raised randomised controlled trial Randomised trial RCT receiving reported respond Result SARS-CoV-2 transmission School Schools self-isolate Self-isolation suggested Testing Topic with COVID-19 [DOI] 10.1186/s12889-022-13204-x PMC 바로가기 [Article Type] Randomized Controlled Trial
OraSure InteliSwab ™ Rapid Antigen Test Performance with the SARS-CoV-2 Variants of Concern-Alpha, Beta, Gamma, Delta, and Omicron알파, 베타, 감마, 델타, 오미크론의 SARS-CoV-2 변종을 사용한 OraSure InteliSwab ™ 신속한 항원 테스트 성능Article Published on 2022-03-062022-09-11 Journal: Viruses [Category] SARS, 변종, 치료기술, 치료법, 치료제, [키워드] Alpha Beta cell culture medium comparable COVID-19 COVID-19 pandemic culture medium Delta diagnostic tests dilution series dilution sery evaluate evaluated FDA function Gamma human population inoculated investigated Lateral flow device limit of detection Limits of detection Lineage no decrease nucleocapsid protein omicron oropharyngeal swab oropharyngeal swabs performance Rapid rapid antigen-detecting test Rapid test Recombinant nucleocapsid protein recorded resulting RNA RNA copies SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 strain sensitivity strain Syrian golden hamster Syrian Golden hamsters Test the SARS-CoV-2 variant variants variants of concern VoC VOCs was determined [DOI] 10.3390/v14030543 PMC 바로가기 [Article Type] Article
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infectivity by Viral Load, S Gene Variants and Demographic Factors, and the Utility of Lateral Flow Devices to Prevent Transmission중증급성호흡기증후군 코로나바이러스 2(SARS-CoV-2) 바이러스 부하, S 유전자 변이체 및 인구통계학적 요인에 의한 감염성, 전파 방지를 위한 측면 흐름 장치의 유용성Major Articles and Commentaries Published on 2022-02-012022-09-10 Journal: Clinical Infectious Diseases: An Official Publicat [Category] COVID19(2023년), MERS, SARS, 변종, 치료기술, 치료제, [키워드] 95% CI 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age Antigen B.1.1.7 B.1.1.7 variant best Chain Reaction children clinical sensitivity Contact Contact tracing coronavirus coronavirus 2 cycle threshold demographic demographics Deprivation detect Device England example expected Flow followed by household contact household contacts incidence index case index cases Infection Infectivity Lateral Lateral flow device less LFD load multivariable logistic regression onward transmission PCR-positive point-of-care polymerase chain polymerase chain reaction positive potential transmission proportion respiratory Result S gene S gene target failure SARS-CoV-2 SARS-CoV-2 testing social deprivation tested Transmission Viral Viral load viral loads [DOI] 10.1093/cid/ciab421 PMC 바로가기 [Article Type] Major Articles and Commentaries
Determining the Prevalence and Incidence of SARS-CoV-2 Infection in Prisons in England: Protocol for a Repeated Panel Survey and Enhanced Outbreak StudyProtocol Published on 2022-01-122022-10-29 Journal: JMIR Research Protocols [Category] COVID-19, [키워드] Analysis antibody calculated Characteristics collected Community condition COVID-19 COVID-19 pandemic Data collection Department Determining Diseases eligible England enhanced enrolled Epidemiology facilitate Factor Factors for inclusion Health Health inequalities Identifier incidence rate include Inclusion individual initial Lateral flow device management nasal swab Nasopharyngeal swab objective outbreak Outbreaks pandemic Panel participant Participants Phase 1 Phase 2 polymerase chain positive Positive test Practitioner prison proportion public health Public Health England repeated report Result SARS-CoV-2 SARS-CoV-2 antigen SARS-COV-2 infection selected Spread staff survey tested Testing unique university Ventilated [DOI] 10.2196/30749 PMC 바로가기 [Article Type] Protocol
Analytical and Clinical Evaluation of the Semiquantitative Elecsys Anti-SARS-CoV-2 Spike Protein Receptor Binding Domain Antibody Assay on the Roche cobas e602 AnalyzerRoche cobas e602 분석기에서 반정량적 Elecsys Anti-SARS-CoV-2 스파이크 단백질 수용체 결합 도메인 항체 분석의 분석 및 임상 평가Article Published on 2022-01-062022-09-11 Journal: American journal of clinical pathology [Category] SARS, 진단, 치료기술, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Analyzer Anti-spike anti-spike antibodies antibodies antibody Bilirubin Biotin clinical clinically Concordance coronavirus COVID-19 COVID-19 patient COVID-19 vaccination cross-reactivity detect diagnostics Elecsy ELISA enzyme-linked immunosorbent enzyme-linked immunosorbent assay evaluate evaluated exhibit greater hemoglobin IgA antibodies IgA antibody IgG IgM immunoassay Interference Lateral flow device linearity measure mRNA Neutralization assay PCR positivity plasma Precision Protein Receptor binding domain respiratory robust Roche SAR-CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein SARS-CoV-2 virus Semiquantitative semiquantitatively Sensitivity and specificity serology Seropositivity serum spike Spike protein triglycerides turn [DOI] 10.1093/ajcp/aqab092 PMC 바로가기 [Article Type] Article