Glycyrrhizin: An alternative drug for the treatment of COVID-19 infection and the associated respiratory syndrome?Article Published on 2020-06-242023-06-14 Journal: Pharmacology & therapeutics [Category] MERS, SARS, [키워드] cholesterol coronavirus COVID-19 CQ, Chloroquine GLR, glycyrrhizin or glycyrrhizinic acid glycyrrhizin HCQ, hydroxychloroquine HMGB1 HMGB1, High-Mobility Group protein B1 LPS, lipopolysaccharide natural product SARS, Severe acute respiratory syndrome TLR4, Toll-Like Receptor 4. [DOI] 10.1016/j.pharmthera.2020.107618 PMC 바로가기 [Article Type] Article
The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor systemArticle Published on 2020-05-112023-06-15 Journal: Cytokine & growth factor reviews [Category] MERS, SARS, [키워드] AP-1, activator protein-1 ARDS, acute respiratory distress syndrome chemokines coronavirus COVID-19 COVID-19, Coronavirus disease 2019 CSF, colony-stimulating factors CXCL10 CXCL8 Cytokine storm DNA, Deoxyribonucleic acid ICU, Intensive Care Units IFN, interferon IL-, interleukin IRF, interferon regulatory transcription factor LPS, lipopolysaccharide MERS-CoV, Middle East respiratory syndrome coronavirus MERS, Middle East respiratory syndrome NF-kB, nuclear factor kappa-light-chain-enhancer of activated B cells PBMCs, peripheral blood mononuclear cells RNA, Ribonucleic acid SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 SARS-CoV, severe acute respiratory syndrome coronavirus SARS, Severe acute respiratory syndrome TH1, T-helper-1 TNF, Tumor Necrosis Factor [DOI] 10.1016/j.cytogfr.2020.05.003 PMC 바로가기 [Article Type] Article
Dietary choline supplementation attenuated high-fat diet-induced inflammation through regulation of lipid metabolism and suppression of NFκB activation in juvenile black seabream ( Acanthopagrus schlegelii )Research Article Published on 2019-11-222023-08-30 Journal: Journal of Nutritional Science [Category] E형 간염, [키워드] accα, acetyl-CoA carboxylase α cpt1a, carnitine palmitoyltransferase 1a fas, fatty acid synthase hsl, hormone-sensitive lipase srebp-1, sterol regulatory element-binding protein-1 tgfβ-1, transforming growth factor β-1 ALT, alanine aminotransferase AST, aspartate aminotransferase choline HFD + C1, HFD + choline (3 g/kg) HFD + C2, HFD + choline (6 g/kg) HFD + C3, HFD + choline (12 g/kg) HFD, High-Fat Diet High-fat diets Inflammation lipid metabolism LPS, lipopolysaccharide NFκB qPCR, quantitative PCR [DOI] 10.1017/jns.2019.34 PMC 바로가기 [Article Type] Research Article
The serine protease inhibitor camostat inhibits influenza virus replication and cytokine production in primary cultures of human tracheal epithelial cellsArticle Published on 2015-07-102023-06-23 Journal: Pulmonary pharmacology & therapeutics [Category] 신종인플루엔자, [키워드] AEBSF, 4-(2-aminoethyl)-benzenesulfonyl fluoride airway epithelial cell ANOVA, analysis of variance camostat Cell culture CLEIA, chemiluminescent enzyme immunoassay COPD, Chronic obstructive pulmonary disease DF-12, mixture of Dulbecco's modified Eagle's medium-Ham's F-12 medium DMEM, Dulbecco's modified Eagle's medium ELISA, enzyme-linked immunosorbent assay F-12, Ham's F-12 medium HA, hemagglutinin HAT, human trypsin-like protease IFN, interferon IL, interleukin Influenza interleukin KIU, Kallikrein Inhibitor Unit LDH, lactate dehydrogenase LPS, lipopolysaccharide MDCK, Madin Darby Canine Kidney MEM, Eagle's minimum essential medium MOI, multiplicity of infection PBS-T, phosphate buffered saline with Tween® 20 PBS, phosphate buffered saline PVDF, polyvinylidene difluoride RT, room temperature SARS-CoV, severe acute respiratory syndrome coronavirus SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis serine protease TCID, tissue culture infective dose TMPRSS, transmembrane protease serine S1 member TNF, Tumor Necrosis Factor USG, Ultroser G [DOI] 10.1016/j.pupt.2015.07.001 PMC 바로가기 [Article Type] Article