lung failure – Page 2 – Communicable Diseases Research

Clinical course of COVID-19 patients needing supplemental oxygen outside the intensive care unit

Observational Study

Published on 2021-01-262022-10-04
Journal: Scientific Reports [Category] 임상, 치료기술, 치료법,

Prone during pandemic: development and implementation of a quality-based protocol for proning severe COVID-19 hypoxic lung failure patients in situationally or historically low resource hospitals

Technical Advance

Published on 2021-01-122022-10-28
Journal: BMC Pulmonary Medicine [Category] COVID-19,

[키워드] acute respiratory distress syndrome (ARDS) age ANOVA approach ARDS Austere environment baseline BMI body mass index Bonferroni correction caused change changes in coefficients country COVID-19 Crew Crew resource management (CRM) death decrease dialysis evaluated High reliability organization (HRO) hospital hypoxic ICU implementation Intermittent IPP limitation limitations Low resource setting Low- and middle-income countries (LMICs) lung failure male Mortality New York organization Patient patients patients with COVID-19 positioning predicted Pressor agent prone prone positioning proning protocol resource respiratory Result SARS CoV-2 severe ARDS severe COVID-19 significant changes in statistically significant supine the patient were used
[DOI] 10.1186/s12890-021-01401-0 PMC 바로가기 [Article Type] Technical Advance

The Two-Way Switch Role of ACE2 in the Treatment of Novel Coronavirus Pneumonia and Underlying Comorbidities

신종 코로나바이러스 폐렴 및 기저 동반 질환의 치료에서 ACE2의 양방향 전환 역할

Review

Published on 2020-12-312022-09-10
Journal: Molecules [Category] MERS, SARS, 치료제,

[키워드] ACE ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 addition analyzed angiotensin angiotensin receptor blocker angiotensin-converting enzyme II (ACE2) anti-SARS-CoV-2 caused Comorbidities coronavirus disease Coronavirus disease 2019 Coronavirus pneumonia Coronavirus-2 COVID-19 described domain drug Drug discovery enzyme II epithelial cells functional globe higher affinity host cells hot spot hypertension Infection information inhibitor interact Intervention lung failure Lung injury membrane-bound Mortality Novel coronavirus novel coronavirus pneumonia Patient pharmacological Pneumonia potential treatment option Protein pulmonary epithelial cells RAS receptor receptor blocker recombinant ACE2 Renin renin-angiotensin system renin-angiotensin system (RAS) respiratory role SARS-CoV-2 SARS-CoV-2 entry SARS-COV-2 infection SARS-CoV-2 spike protein Severe acute respiratory syndrome Severe acute respiratory syndrome (SARS) severe acute respiratory syndrome Coronavirus Spike protein Spread suggested switch the SARS-CoV-2 therapeutic strategy Treatment Viral
[DOI] 10.3390/molecules26010142 PMC 바로가기 [Article Type] Review

Inhibition of SARS-CoV-2 Entry into Host Cells Using Small Molecules

Review

Published on 2020-12-082022-10-28
Journal: Pharmaceuticals [Category] COVID-19,

A potential hypothesis for 2019-nCoV infection therapy through delivery of recombinant ACE2 by red blood cell-hitchhiking

Hypothesis

Published on 2020-12-072022-10-30
Journal: Journal of Biological Research [Category] COVID-19,

Evaluation of current diagnostic methods for COVID-19

Reviews

Published on 2020-12-012022-10-28
Journal: APL Bioengineering [Category] COVID-19,

[키워드] acute respiratory syndrome aerosol droplets antibody Antigen approach caused Clinical finding contagious coronavirus coronavirus disease COVID-19 diagnosed diagnosis of COVID-19 diagnostic Diagnostic method economic loss enzyme-linked immunosorbent assays evaluated fluorescent hospital Human immunoassays immunochromatographic immunofluorescence immunological assay include Laboratory tests lung failure Molecular assay Molecular tests multi-organ dysfunction outbreak pandemic Perspective Pneumonia polymerase chain reactions positive Prevent reached required responsible SARS-CoV-2 single-stranded RNA virus Spread transmitted Trigger virus virus isolation
[DOI] 10.1063/5.0021554 PMC 바로가기 [Article Type] Reviews

Lung Ultrasound in Severe COVID-19 Pneumonia in the Sub-Intensive Care Unit: Beyond the Diagnostic Purpose

Case report

Published on 2020-11-272022-10-05
Journal: Respiratory Medicine Case Reports [Category] 진단,

Cellular senescence as a potential mediator of COVID‐19 severity in the elderly

Review

Published on 2020-09-212022-10-28
Journal: Aging Cell [Category] COVID-19, MERS, SARS,

[키워드] accumulate advanced age alleviate association Biomarker cellular cellular senescence characterized complex Consequences contribute coronavirus disease COVID‐19 COVID‐19 patient Cytokine storm detrimental disease disease severity distress early phase Efficacy evaluate Factor functional growth Health identifying IMPROVE individual infect inflammatory reaction limit Lower respiratory tract lung failure mechanism novel Betacoronavirus Older Pathogenesis Prevent promote rising mortality risk SARS‐CoV‐2 SARS‐CoV‐2 infection second senescence senescent cell severe complication severity syndrome the disease therapy tissue damage Vaccinations Vaccine vaccine response
[DOI] 10.1111/acel.13237 PMC 바로가기 [Article Type] Review

Prospects for RNAi Therapy of COVID-19

Bioengineering and Biotechnology

Published on 2020-07-302022-10-31
Journal: Frontiers in Bioengineering and Biotechnology [Category] COVID-19,

[키워드] acute respiratory disease Analysis Anti-viral drugs approach approaches approved authors binding caused clinical setting Consequences COVID-19 develop drug delivery drug treatment duplication effective effective intervention emerging disease Factor faster feasibility Host host response immune system Infection limitation lung lung failure lung tissue mechanism modulating molecular nucleic acid pandemic Perspective pulmonary system Region Respiratory function resulting RNA RNA interference SARS-CoV SARS-CoV-2 siRNA target targets the SARS-CoV-2 the SARS-CoV-2 virus Therapeutic approach therapeutic target Therapies therapy translate urgency Vaccine viral entry viral genome viral spread virus
[DOI] 10.3389/fbioe.2020.00916 PMC 바로가기 [Article Type] Bioengineering and Biotechnology

COVID-19: is it just a lung disease? A case-based review

Covid-19

Published on 2020-07-282022-10-29
Journal: Sn Comprehensive Clinical Medicine [Category] COVID-19,

[키워드] “cardiac pathology” “central nervous system” “COVID-19” “OR” “SARS” “OR” “SARS – COV 2” “AND” “systemic disease” “nephropathy” acute kidney failure affected airways Brain Case series case sery caused clinical clinical presentation coronavirus COVID-19 COVID-19 virus develop disease Evidence extreme feature include Infection liver lung lung failure majority Medicine Meta-analysis myocarditis pandemic paper pathology problems RCTs reproductive Research respiratory tract selected severe COVID-19 Spread syndrome systematic reviews systemic damage systemic disease virulence ward
[DOI] 10.1007/s42399-020-00418-6 PMC 바로가기 [Article Type] Covid-19