Angiotensin II induces reactive oxygen species, DNA damage, and T cell apoptosis in severe COVID-19
Research article
Published on
Journal: The Journal of Allergy and Clinical Immunology
[Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘,
Journal: The Journal of Allergy and Clinical Immunology
[Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘,
[키워드] ACE2
acute respiratory syndrome
Admission
age
Angiotensin II
angiotensin II receptor
angiotensin-converting enzyme 2
antioxidant
Apoptosis
coronavirus
coronavirus disease
COVID-19
COVID-19 pathogenesis
death
DNA damage
DNA oxidation
ELISA
flow cytometry
form
healthy controls
high plasma level
ICU
ICU Patients
immunofluorescence
induce
infected with SARS-CoV-2
Infection
intensity
intensive care
Lymphocyte count
Lymphocytes
lymphopenia
monocyte
neighboring cells
objective
oxidative stress
Patient
patients
patients with COVID-19
PBMC
Predictive
programmed cell death
protease
reactive oxygen species
reactive oxygen specy
receptor
released
responsible
Result
ROS
ROS production
SARS-CoV-2
severe COVID-19
survival
T cell
T-cell
Trigger
was measured
were measured
[DOI] 10.1016/j.jaci.2022.06.020 [Article Type] Research article
[DOI] 10.1016/j.jaci.2022.06.020 [Article Type] Research article