Natural SARS-CoV-2 Infection in a Free-Ranging Black-Tailed Marmoset (Mico melanurus) from an Urban Area in Mid-West Brazil브라질 중서부 도시 지역의 자유 범위 검은꼬리 마모셋(Mico melanurus)에서 자연적인 SARS-CoV-2 감염Article Published on 2022-06-012022-09-11 Journal: Journal of comparative pathology [Category] COVID19(2023년), SARS, 치료기술, 치료법, [키워드] alveolar septa animal Antigen Area Black-Tailed Marmoset Brazil clinical history COVID-19 female Hepatitis Host human populations immunohistochemistry Interstitial nephritis intestine large intestine liver lung lung tissue Lymph node Lymphocytes lymphoid marmoset Mild motor vehicle nasopharyngeal natural natural infection necropsy New World New World monkey nodule one health oropharyngeal swab pathogen Pathogens peribronchial periportal platyrrhines. Polytrauma pool Protein risk SARS-CoV-2 SARS-COV-2 infection Spike protein spleen state the viral nucleocapsid urban urban area viral nucleocapsid protein Viral RNA viral RNA detection [DOI] 10.1016/j.jcpa.2022.03.005 PMC 바로가기 [Article Type] Article
Anti-SARS-CoV-2 antibody response after 2 and 3 doses of BNT162b2 mRNA vaccine in patients with lymphoid malignancies림프성 악성종양 환자에서 BNT162b2 mRNA 백신 2회 및 3회 투여 후 항-SARS-CoV-2 항체 반응Article Published on 2022-06-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] affected anti-CD20 Anti-CD20 antibodies Anti-CD20 antibody anti-CD38 anti-RBD Anti-RBD IgG antibody antibody concentration Antibody concentrations Antibody Response B-cell malignancies B-cell malignancy benefit binding domain booster Cell Cohort Concentration conducted Course COVID-19 COVID-19 patient COVID-19 patients disorders dose effective evaluate haematological malignancies haematological malignancy Haematologicalmalignancies humoral Humoral response humoral responses IgG Immunocompromised increment IQR lymphoid lymphomas malignancies malignancy median monoclonal Mortality mRNA vaccination mRNA vaccine of BNT162b2 Patient patients patients treated plasma Plasma cell Prophylaxis quantification RBD SARS-CoV-2 Seroconversion seroconversion rate seroconverted serological serological response serology significantly spike the disease the vaccine therapy third dose Vaccine vaccine dose [DOI] 10.1016/j.cmi.2022.02.029 PMC 바로가기 [Article Type] Article
Humoral response to mRNA-based COVID-19 vaccine in patients with myeloid malignancies골수성 악성종양 환자에서 mRNA 기반 코로나19 백신에 대한 체액 반응Article Published on 2022-06-012022-09-12 Journal: British Journal of Haematology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute myeloid leukaemia AML Anti-spike Antibody titre appear comparable COVID-19 COVID-19 vaccine disease HCs healthy control humoral Humoral response Infection lymphoid malignancies malignancy MDs mRNA-based mRNA-based COVID-19 vaccine myelodysplastic syndrome. myeloid malignancies myeloid malignancy no significant difference Patient patients risk SARS-CoV-2 SARS-CoV-2 antibody titre SARS-CoV-2 vaccine significantly lower syndrome therapy Treatment vaccination Vaccine were measured [DOI] 10.1111/bjh.18138 PMC 바로가기 [Article Type] Article
Risk and Outcome of Breakthrough COVID-19 Infections in Vaccinated Patients With Cancer: Real-World Evidence From the National COVID Cohort Collaborative백신 접종을 받은 암 환자의 획기적인 COVID-19 감염의 위험과 결과: 국가 COVID 코호트 협력의 실제 증거Article Published on 2022-05-012022-09-11 Journal: Journal of clinical oncology : official journal of [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI adjusted age analyzed BNT162b2 BNT162b2 vaccine Bone marrow Bone marrow transplantation booster Breakthrough infection breakthrough infections Cancer cancers Cohort controls COVID COVID-19 COVID-19 case COVID-19 cases COVID-19 infection COVID-19 infections Evidence hematologic Hematologic malignancy higher risk identify immunosuppressive effect increased risk leukemia Logistic regression lymphoid lymphoma malignancies medications Moderna mRNA COVID-19 vaccine mRNA COVID-19 vaccines mRNA-1273 Multiple myeloma Myeloma National new SARS-CoV-2 Odds ratios outcome outcomes Patient patients Patients with cancer Pfizer ranged risk SARS-COV-2 infection SARS-CoV-2 variants Sex significantly higher smoking smoking status Solid solid tumors Tumor tumors vaccination Vaccine vaccine dose variants was reduced [DOI] 10.1200/JCO.21.02419 PMC 바로가기 [Article Type] Article
Evaluation of Antibody Response to SARS-CoV-2 mRNA-1273 Vaccination in Patients With Cancer in Florida플로리다의 암 환자에서 SARS-CoV-2 mRNA-1273 백신 접종에 대한 항체 반응 평가Article Published on 2022-05-012022-09-12 Journal: JAMA Oncology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] 95% CI age anti-CD20 anti-CD20 treatment antibody Antibody Response applied blood test calculated Cancer cancer diagnosis cancer type cohort study diagnose dose doses English enzyme-linked immunosorbent Factor geometric mean titer hematologic Hispanic IgG IgG level Immunosuppressive treatment individual lowest lymphocyte lymphoid monoclonal antibody treatment morbidity and mortality mRNA-1273 Older outcome participant Patient patients treated Patients with cancer receipt receiving response SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 spike protein SARS-CoV-2 vaccine Seroconversion Seropositivity significantly lower small molecule solid tumor Spanish T Test treated Treatment vaccination vaccine dose vaccine response white [DOI] 10.1001/jamaoncol.2022.0001 PMC 바로가기 [Article Type] Article
Dysregulation of the leukocyte signaling landscape during acute COVID-19급성 COVID-19 동안 백혈구 신호 전달 환경의 조절 장애Article Published on 2022-04-142022-09-12 Journal: PLoS ONE [Category] 진단, [키워드] Activation acute COVID-19 approach Cell cellular activation circulating claimed correlated COVID-19 COVID-19 pandemic Cytometry driving dysregulated functional IFN-γ IL-6 level immune dysfunction immune effector cell immune function immune system immunology Immunosuppression Inflammation leukocyte lung lymphoid marker mechanism molecular mechanism monocyte myeloid cell pathogenesis of COVID-19 pathophysiologic phosphoproteome Phosphorylation populations Signaling signaling pathway STAT3 suppressed systemic inflammatory response T cell T cells These data tissue injury [DOI] 10.1371/journal.pone.0264979 PMC 바로가기 [Article Type] Article
Persistence of SARS-CoV-2 Infection in Severely Immunocompromised Patients With Complete Remission B-Cell Lymphoma and Anti-CD20 Monoclonal Antibody Therapy: A Case Report of Two Cases완전 관해 B-세포 림프종 및 항-CD20 단일클론항체 치료를 받은 중증 면역저하 환자에서 SARS-CoV-2 감염 지속: 2건의 증례 보고Randomized Controlled Trial Published on 2022-04-142022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 임상, 진단, [키워드] acute infection acute respiratory syndrome anti-CD20 B-cell lymphoma Case report condition coronavirus coronavirus disease Corticosteroids COVID-19 described Evidence Hematological malignancy Hyperimmune plasma Immunocompromised Immunosuppressant Infection information lymphoid lymphoma malignancy Nasopharyngeal swab Patient plasma positive Randomized controlled trials receiving Remdesivir Remission report risk rituximab RT-PCR SARS-CoV-2 subgroup of patient susceptible therapy treated Treatment viral replication [DOI] 10.3389/fimmu.2022.860891 PMC 바로가기 [Article Type] Randomized Controlled Trial
Convalescent plasma improves overall survival in patients with B-cell lymphoid malignancy and COVID-19: a longitudinal cohort and propensity score analysis회복기 혈장은 B세포 림프성 악성종양 및 COVID-19 환자의 전체 생존율을 향상시킵니다: 종단 코호트 및 성향 점수 분석Article Published on 2022-04-012022-09-12 Journal: Leukemia [Category] COVID19(2023년), MERS, SARS, 임상, 진단, 치료법, [키워드] 95% CI age anti-CD20 appear approach B-cell blood pressure CCP Cohort convalescent plasma COVID-19 COVID-19 patient COVID-19 severity decreased mortality disease Hematological malignancy high mortality rate humoral humoral immune response Immunosuppression impair IMPROVE lymphoid malignancy monoclonal antibody neoplasm neutralizing antibody outcome Patient patients plasma Probability propensity score analysis SARS-CoV-2 Sensitivity analyses specific treatment subgroups of patient survival therapy transfer treated Treatment underlying disease viral clearance Weighting [DOI] 10.1038/s41375-022-01511-6 PMC 바로가기 [Article Type] Article
Severe COVID-19 is characterised by inflammation and immature myeloid cells early in disease progressionResearch article Published on 2022-04-012022-10-05 Journal: Heliyon [Category] 바이오마커, 진단, [키워드] Analysis average Biomarkers carried cause CD10 COVID-19 CRP demonstrated diagnostic Disease progression disease severity eight elevated expression feature hospital identify identifying IL-6 immature Immune phenotype immunological immunological characteristics Inflammation Laboratory lymphoid machine learning management marker monocyte myeloid cell Neutrophil maturity Neutrophils Patient positive SARS-CoV-2 PCR pro-inflammatory cytokine progression recruited risk factor routine SARS-COV-2 infection severe COVID-19 severe disease soluble CD25 were measured [DOI] 10.1016/j.heliyon.2022.e09230 [Article Type] Research article
From Deer-to-Deer: SARS-CoV-2 is efficiently transmitted and presents broad tissue tropism and replication sites in white-tailed deer사슴에서 사슴으로: SARS-CoV-2는 효율적으로 전염되며 흰꼬리사슴의 광범위한 조직 친화성과 복제 부위를 나타냅니다.Article Published on 2022-03-212022-09-11 Journal: PLoS Pathogens [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus added age Americas B.1 lineage causative agent Central nervous system Contact coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Critical deer demonstrated disease disease control effective host range humans hunting implementation infect Infection Infectious virus intranasal investigated lack lymphoid Measures nasal natural infection Odocoileus Prevent provide replication site reported reservoir SARS-CoV-2 SARS-CoV-2 replication severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 shown susceptible tissue tropism tissues Transmission Transmission dynamics transmitted tropism Viral load virus virus replication white-tailed deer wild animal zoonotic transmission [DOI] 10.1371/journal.ppat.1010197 PMC 바로가기 [Article Type] Article