make up – Page 2 – Communicable Diseases Research

SARS-CoV-2 genomic characterization and clinical manifestation of the COVID-19 outbreak in Uruguay

우루과이에서 발생한 COVID-19 발병의 SARS-CoV-2 게놈 특성 및 임상 징후

Coronaviruses

Published on 2021-01-152022-09-10
Journal: Emerging Microbes & Infections [Category] SARS, 변종, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis Arterial hypertension association caused clade clinical correlations clinical parameter Cohort contribute coronavirus correlated correlation COVID-19 COVID-19 outbreak D614G D614G mutation disease dominance FIVE full genome amplicon sequencing Genetic genomic global public health global public health emergency Health Organization Healthcare system hypertension ICU admission independent Inpatients kidney Kidney failure Latin America Local make up minimum Mutation non-structural protein outbreak outcome outpatients and inpatient pandemic partial lockdown performed phylodynamic phylogeographic analysis phylogeographic BEAST analysis respiratory Respiratory illness resulting SARS-CoV-2 SARS-COV-2 infection sequence sequenced sequences severe acute respiratory syndrome Coronavirus significantly South South America spike D614G genetic mutation the SARS-CoV-2 Transmission transmission clusters transmissions Uruguay Viral viral genome viral genomes viral strain viral strains virus World Health Organization
[DOI] 10.1080/22221751.2020.1863747 PMC 바로가기 [Article Type] Coronaviruses

Pervasive generation of non-canonical subgenomic RNAs by SARS-CoV-2

SARS-CoV-2에 의한 비정규 서브게놈 RNA의 광범위한 생성

Research

Published on 2020-12-012022-08-13
Journal: Genome Medicine [Category] MERS, SARS, 유전자 메커니즘,

[키워드] 3′ end 5′ UTR abundance accessory protein addition Analysis approaches canonical canonical sgRNA canonical sgRNAs caused Cell culture condition Consistency Coordinate coronavirus disease Coronavirus disease 2019 Coverage COVID-19 determine Direct RNA sequencing eight Evidence family Coronaviridae FIVE generate Genome highlight homology Host identify in viral increase in independent Infection information Integrative analysis junction landscape leader sequence make up nc-sgRNA nc-sgRNAs non-canonical sgRNA non-canonical sgRNAs non-canonical subgenomic RNA offer open reading frames ORF ORF1a ORFs positive-sense RNA virus Region reported Result RNA RNA virus SARS-CoV-2 SARS-CoV-2 biology SARS-CoV-2 genome SARS-CoV-2 pathogenesis SARS-CoV-2 RNA SARS-CoV-2 sgRNA SARS-CoV-2 sgRNAs SARS-CoV-2 transcriptome SARS-CoV-2 transcriptomes sequence sequences Sequencing Seven sgRNA sgRNAs subgenomic RNA subgenomic RNAs supplementary material the SARS-CoV-2 genome Transcription transcriptional activity transcriptional regulatory sequence transcriptional regulatory sequences transcriptomes TRS TRS-B TRS-L Viral viral isolate viral isolates viral RNAs was used worldwide pandemic
[DOI] 10.1186/s13073-020-00802-w PMC 바로가기 [Article Type] Research