metastatic disease – Page 2 – Communicable Diseases Research

Safety and preliminary efficacy of the Gam-COVID-Vac vaccine and outcomes of SARS-CoV-2 infection in Russian patients with genitourinary malignancies

Clinical Trial

Published on 2021-11-132022-10-04
Journal: Journal of Hematology & Oncology [Category] MERS, SARS, 임상,

Association Between Androgen Deprivation Therapy and Mortality Among Patients With Prostate Cancer and COVID-19

Research

Published on 2021-11-122022-10-29
Journal: JAMA Network Open [Category] COVID-19, MERS,

[키워드] 30-Day mortality 95% CI adjusted Administered age Analysis analyzed androgen association baseline body mass index Cancer center clinical trial cohort study collected Comorbidity Cooperative COVID-19 COVID-19 diagnosis COVID-19 infection decrease decreased mortality defined Deprivation diabetes diagnosis of cancer Evidence exposure expression finding Follow-up group Importance Infection Initially Kidney disease maintain measure median age men metastatic disease Mortality mortality rate neoplasm no significant difference objective Older Orchiectomy participant Patient patient data patients patients with COVID-19 performance status Point primary end point Primary outcome propensity score matching Prostate Prostate cancer protease receive receiving recorded reducing Relevance Result SARS-COV-2 infection serine 2 setting severity smoking status statistically significant difference Support the SARS-CoV-2 therapy TMPRSS2 transmembrane treated Treatment university was performed were excluded white with COVID-19 women
[DOI] 10.1001/jamanetworkopen.2021.34330 PMC 바로가기 [Article Type] Research

Counterbalancing COVID-19 with Cancer Surveillance and Therapy: A Survey of Patients with Renal Cell Carcinoma

Research article

Published on 2021-11-012022-10-05
Journal: European Urology Focus [Category] SARS, 유전자 메커니즘,

COVID-19 vaccines in adult cancer patients with solid tumours undergoing active treatment: Seropositivity and safety. A prospective observational study in Italy

Research article

Published on 2021-11-012022-10-05
Journal: European journal of cancer (Oxford, England : 1990 [Category] SARS, 치료법,

[키워드] administration antibodies antibody anticancer anticancer treatment baseline BNT162b2 Cancer cancer patient Cancer patients cancer progression composed conducted consecutive patient control group coronavirus disease COVID-19 COVID-19 antibody COVID-19 infection COVID-19 pandemic COVID-19 vaccination COVID-19 vaccine evaluate evaluated Factor GRADE healthy volunteers high risk IgG IgG titer immunogenic Italy Male sex median median age metastatic disease Patient prospective observational study receive reported Result RNA-1273 safety profile SARS-CoV-2 second dose secondary Seroconversion Seropositivity serum sample Side-effects significantly lower solid cancer solid tumour the vaccine therapy Treatment tumour two-dose regimen vaccination Vaccine vaccine dose were excluded
[DOI] 10.1016/j.ejca.2021.08.035 [Article Type] Research article

Mortality and critical care unit admission associated with the SARS-CoV-2 lineage B.1.1.7 in England: an observational cohort study

영국의 SARS-CoV-2 계통 B.1.1.7과 관련된 사망률 및 중환자실 입원: 관찰 코호트 연구

Observational Study

Published on 2021-11-012022-09-10
Journal: The Lancet. Infectious Diseases [Category] MERS, SARS, 변종, 임상,

[키워드] 28-day mortality 95% CI adjusted adjusted hazard ratio adjusted hazard ratios Admission age association Asthma Audit B.1.1.7 body-mass body-mass index cardiovascular disease case mix CCU chronic obstructive chronic obstructive pulmonary disease Clinical outcome clinical outcomes Cohort Community Comorbidities Comorbidity COVID-19 test COVID-19 testing Critical care Critically ill dependency Deprivation diabetes diagnostic died division Ethnicity exposure to finding funding geographical region groups hazard ratios hospital HRs hypertension immunocompromised condition increased risk independent independent of Infection infection with COVID-19 information Lineage Lineage B.1.1.7 measure Medical Science metastatic disease molecular Mortality National Observational cohort study obstructive pulmonary disease on type on types organ support overall mortality Oxford Patient patients with SARS-CoV-2 positive positive sample primary care Public Health England pulmonary disease QResearch receiving reported respiratory Respiratory disease risk S-gene SARS-CoV-2 SARS-COV-2 infection Sex smoking status Sociodemographic factor the SARS-CoV-2 two groups University of Oxford variant variant of SARS-CoV-2 virus strain Wellcome Trust
[DOI] 10.1016/S1473-3099(21)00318-2 PMC 바로가기 [Article Type] Observational Study

High mortality among patients with cancer and COVID-19 infection: the experience of a Brazilian cancer center

Original Article

Published on 2021-10-262022-10-31
Journal: Einstein [Category] COVID-19, MERS, SARS,

[키워드] 105 patient Admission age Analysis analyzed anticancer assist benefit Cancer Cancer center cancer patient Cohort Comorbidities Cooperative Coronavirus infections COVID-19 COVID-19 diagnosis database diagnosis of COVID-19 died e COVID-19 epidemiological evaluate Evolução fatal Factor Fatal outcome feature females finding group high mortality hospital infecção Infection initial symptom intensive care Isolation Laboratory male mechanical ventilation metastatic disease Mortalidade Mortality Neoplasias Neoplasms objective outcome overall mortality Pandemia Pandemias pandemic Pandemics Patient Patients with cancer performance status prevalent reduce Result retrieved retrospective data SARS-CoV-2 SARS-CoV-2, Infecções por coronavírus severity of COVID-19 Sex therapy
[DOI] 10.31744/einstein_journal/2021AO6254 PMC 바로가기 [Article Type] Original Article

Impact of telemedicine adoption on accessibility and time to treatment in patients with thoracic malignancies during the COVID-19 pandemic

Research Article

Published on 2021-10-112022-10-28
Journal: BMC Cancer [Category] COVID-19, MERS,

PRO B: evaluating the effect of an alarm-based patient-reported outcome monitoring compared with usual care in metastatic breast cancer patients—study protocol for a randomised controlled trial

PRO B: 전이성 유방암 환자에서 일반 치료와 비교하여 경보 기반 환자 보고 결과 모니터링의 효과 평가 - 무작위 대조 시험을 위한 연구 프로토콜

Study Protocol

Published on 2021-09-282022-09-10
Journal: Trials [Category] SARS, 임상,

[키워드] 1:1 acute disease alarm among others approach ARMS Breast cancer breast cancer patient clinical Clinical practice Complete Contact control arm Controlled trial controls determined by develop disease domain elongation emergency room Endpoint enrolment ePROs fatigue female form Health apps hospitalisation hospitalisations identify include independent intervene Intervention intervention arm intervention group less life Metastatic breast cancer metastatic disease mobile devices outcome Patient Patient-reported outcomes Personalised medicine positive Primary outcome pros protocol Quality of life randomisation randomised randomised controlled trial receive recruited reported symptom reported symptoms required Research secondary Secondary endpoints selected Society supplementary material survival the patient transfer Treatment Trial Trigger usual care Value-based health care
[DOI] 10.1186/s13063-021-05642-6 PMC 바로가기 [Article Type] Study Protocol

Negative Impact of COVID-19 Upon Primary Brain Tumor Care

Neurology

Published on 2021-09-072022-10-31
Journal: Cureus [Category] COVID-19,

Mortality of patients with solid and haematological cancers presenting with symptoms of COVID-19 with vs without detectable SARS-COV-2: a French nationwide prospective cohort study

검출 가능한 SARS-COV-2 유무에 따른 COVID-19 증상을 보이는 고형암 및 혈액암 환자의 사망률: 프랑스 전국 전향 코호트 연구

Article

Published on 2021-08-012022-09-11
Journal: British Journal of Cancer [Category] SARS, 임상, 치료기술, 치료법,

[키워드] 28-day mortality age anticancer Cancer cancer centre cancer patient Cancer patients cancers cause of death clinical clinical symptom Clinical symptoms COVID COVID-19 COVID-19 case COVID-19 diagnosis COVID-19 negative COVID-19 positive patient COVID-19 positive patients COVID-19 symptom COVID-19 symptoms CT-scan death detectable diabete diabetes diagnosed enrolled Follow-up French Gender Haematological cancer high risk hospital immunosuppressive inclusion criteria independent risk factor independent risk factors lymphopenia median metastatic disease Mortality occurred over Patient patients positive positive patients presenting prospective cohort prospective cohort study receiving Registered repeated reported RT-PCR SARS-CoV-2 RT-PCR SARS-CoV2 suspicion symptoms of COVID-19 Treatment Trial
[DOI] 10.1038/s41416-021-01452-4 PMC 바로가기 [Article Type] Article