Systematic evaluation of plasma signaling cascades by functional proteomics approaches: SARS-CoV-2 infection as modelArticle Published on 2022-11-012023-07-10 Journal: Proteomics. Clinical applications [Category] COVID19(2023년), [키워드] acute phase reactant antibody COVID-19 Functional proteomics High-throughput screening immune system Inflammation Microarray [DOI] 10.1002/prca.202100100 PMC 바로가기
Characterization of pathogen-inactivated COVID-19 convalescent plasma and responses in transfused patientsArticle Published on 2022-10-012022-11-15 Journal: Transfusion [Category] COVID19(2023년), SARS, 진단, [키워드] 28-day mortality acute respiratory syndrome administration adverse effects adverse event adverse events antibody antibody assay Antibody Response Antibody titers Antigen assays binding case-control study CCP Characteristics characterization Control Controlled trial convalescent convalescent plasma coronavirus COVID-19 COVID-19 convalescent plasma died disease severity Donor donors enrolled evaluated group had no heterogeneous hospital Hospitalized immune response Immunosuppressed median median age Microarray NAb Neutralizing Neutralizing activity Neutralizing antibodies neutralizing antibody neutralizing antibody assays neutralizing capacity not affect pathogen-reduction treatment. Patient Pneumonia recipient recipients response responses SARS CoV-2 SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV2 single-center survival symptom onset transfused transfusion treated Treatment variable with COVID-19 [DOI] 10.1111/trf.17083 PMC 바로가기
Rapid and quantitative detection of multiple antibodies against SARS-CoV-2 mutant proteins by photo-immobilized microarrayArticle Published on 2022-10-012022-11-15 Journal: Analytical sciences : the international journal of the Japan Society for [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] antibody Antibody assays Antibody detection aqueous solution automatically Blood blood test coated collected condition correlated COVID-19 Diagnosis diagnostic facilitate IgG Immune status immunoassay immunochromatography increase in individual Infection Microarray mutant mutant protein mutant virus Mutation Polymer polymers produced Protein Quantitative Rapid SARS-CoV-2 sera serum the patient vaccinated individuals viral infectious disease virus [DOI] 10.1007/s44211-022-00161-z PMC 바로가기
Highly perturbed genes and hub genes associated with type 2 diabetes in different tissues of adult humans: a bioinformatics analytic workflowArticle Published on 2022-10-012022-11-16 Journal: Functional & integrative genomics [Category] meta-analysis, [키워드] Analysis Apoptosis applied approach association bioinformatics cell type complex defined diabete diabetes Differential gene expression differentially expressed gene downregulated downstream analysis eligible etiology FIVE Gene Expression Gene Expression Omnibus Genes Genetic greater Highly perturbed genes hub gene hub genes identify insulin Kyoto Manifestations marker gene Meta-analysis metabolomics Microarray non-specific ontologies Pathogenesis pathophysiological pathway Pathways Perturbation profiles provided random effect significantly systematic review T2D tissue Type type 2 diabete type 2 diabetes upregulated utility [DOI] 10.1007/s10142-022-00881-5 PMC 바로가기
Advancement and Challenges of Biosensing Using Field Effect Transistors전계효과 트랜지스터를 이용한 바이오센싱의 발전과 과제Review Published on 2022-08-172022-09-11 Journal: Biosensors [Category] SARS, 치료기술, [키워드] accompanied advancement approaches biosensors carried challenge coronavirus coronavirus disease COVID-19 pandemic Debye Debye length degrade Detection sensitivity Device direction domain Effect effective faster field field effect transistors field-effect transistor functional functionalization mechanism Microarray Modification modifications pace Pathogens provided raised SARS-CoV-2 spike protein Screening sensitivity specificity Spike protein surface area the SARS-CoV-2 transistor Transport [DOI] 10.3390/bios12080647 PMC 바로가기 [Article Type] Review
Skin-patch delivered subunit vaccine induces broadly neutralising antibodies against SARS-CoV-2 variants of concern피부 패치 전달 소단위 백신은 우려되는 SARS-CoV-2 변이체에 대한 광범위 중화 항체 유도Article Published on 2022-08-122022-09-11 Journal: Vaccine [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] booster circulation COVID-19 Delta demonstrated dominant Efficacy Health high-density highlight Immunity immunized induce mice Microarray Microarray patch Mutation neutralisation Neutralising Antibodies neutralising antibody omicron Omicron variant resulting robust SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2 variant serum Spike protein subunit Subunit vaccine tested the spike protein Vaccine variant variants variants of concern Viral viral strain Viral variants [DOI] 10.1016/j.vaccine.2022.07.013 PMC 바로가기 [Article Type] Article
Anti-neuronal antibodies against brainstem antigens are associated with COVID-19Article Published on 2022-08-112022-10-05 Journal: EBioMedicine [Category] SARS, 바이오마커, 변종, 진단, 치료기술, [키워드] Affect AIFM1 antibody Antigen appear assisted ventilation Autoimmunity Brainstem Control controls Course COVID-19 patient COVID-19 patients DAB1 determine diagnostic Disabled Economy elevated Encephalitis epitope Epitopes finding foundation funding Germany Greifswald group help homolog hypothesised IgG IgG and IgM IgG level IgM implicated in both groups initiative intensive care Invasion long-COVID marker Medicine Microarray Mild Occurrence pathogenic pathway Patient peptide epitope predicted responsible SARS-CoV-2 serum severe disease severely ill patient significantly state Support SURF1 the disease therapeutic understanding university unlikely with COVID-19 [DOI] 10.1016/j.ebiom.2022.104211 [Article Type] Article
Ovarian granulosa cells from women with PCOS express low levels of SARS-CoV-2 receptors and co-factorsPCOS가 있는 여성의 난소 과립막 세포는 낮은 수준의 SARS-CoV-2 수용체 및 보조 인자를 발현합니다Article Published on 2022-08-012022-09-11 Journal: Archives of gynecology and obstetrics [Category] COVID19(2023년), SARS, 치료기술, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus BSG cardiovascular disease Cell cell types co-morbidities controls coronavirus COVID-19 CTSB CTSL datasets death diabetes DPP4 Express expresse expression Factor feature global pandemic granulosa healthy help Human in vitro In vitro fertilization indicate Infection investigated IVF knowledge Lower lower expression material Microarray microarray data morbidities obesity Oocyte organ ovarian ovarian follicle Ovarian granulosa cells Ovary pandemic PCOS polycystic ovary protease receptor reproductive risk Safe SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 receptor severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 susceptibility susceptible syndrome tissue TMPRSS2 Type-2 diabetes mellitus women [DOI] 10.1007/s00404-022-06567-4 PMC 바로가기 [Article Type] Article
Anti-Phospholipid Antibodies and Coronavirus Disease 2019: Vaccination Does Not Trigger Early Autoantibody Production in Healthcare Workers항인지질 항체 및 코로나바이러스 질병 2019: 예방접종은 의료 종사자의 조기 자가항체 생산을 유발하지 않습니다Article Published on 2022-07-152022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome adenovirus-based Anti-phospholipid antibodies antibody autoantibodies autoantibody autoimmune disorder Autoimmune response Autoimmunity BNT162b2 ChAdOx1 characteristic Cohort contribute contributing to coronavirus coronavirus disease COVID-19 cross-reactive dose elicit example Follow-up glycoprotein healthcare healthcare worker human protein IgA IgG IgM immunization Immunoglobulin immunothrombosis injection investigated Microarray molecular not affect Occurrence organ performed Production proteome reactivity reported RNA SARS-CoV-2 SARS-CoV-2 vaccination Support tested the disease thought tissue damage Trigger vaccination Vaccine Vaccines virus spike protein with COVID-19 worker [DOI] 10.3389/fimmu.2022.930074 PMC 바로가기 [Article Type] Article
Screening the hub genes and analyzing the mechanisms in discharged COVID-19 patients retesting positive through bioinformatics analysis생물정보학 분석을 통해 퇴원한 코로나19 환자 재검사에서 허브 유전자 스크리닝 및 기전 분석Article Published on 2022-07-012022-09-11 Journal: Journal of Clinical Laboratory Analysis [Category] 유전자 메커니즘, [키워드] ALKBH6 AMBRA1 Analysis analyzed ANAPC1 Apoptosis ATP1A1 ATP1A1-AS1 bioinformatics Bioinformatics analysis convalescent COVID-19 COVID-19 patient COVID-19 patients cytoHubba differentially expressed gene discharge discharged DISP1 DOCK4 down-regulated down-regulated gene enrichment analysis expression data FAM149B1 FAM241B Gene Expression Omnibus Gene ontology Genes genomes GEO healthy control hub genes IGLV1-40 immune immune response KEGG Kyoto LRRC69 management mechanism MICAL3 Microarray MIR1249 mRNA Pathogenesis Patient patients PLPPR2 positive PPI PPI network Prognosis prognostic protein-protein interaction PSMG1 R software Rab11b RAB11B-AS1 retesting positive after discharged. Ribonucleic acid risk screened Screening selected significant enrichment SNRPD1 SNRPD2 SORT1 TP53BP1 TRAV18 two group two groups up-regulated virus was performed [DOI] 10.1002/jcla.24495 PMC 바로가기 [Article Type] Article